Term
| Chlamydia is an obligate intracellular organism that cannot make ______. |
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Definition
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Term
| extracellular elementary body in chlamydia |
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Definition
infectious
resistant to drying
metabolically inactive |
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Term
| intracellular reticulate body in chlamydia |
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Definition
active
divides
produces new elementary bodies (inclusion bodies) |
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Term
| Like bacteria, chlamydia have both ____ and ____. |
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Definition
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Term
| How do chlamydia reproduce? |
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Definition
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Term
| How are chlamydia similar to bacteria? |
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Definition
-small like smallest bacteria
-have both DNA and RNA
-sensitive to antibiotics |
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Term
| How are chlamydia similar to viruses? |
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Definition
-intracellular
-size of largest viruses
-cannot generate ATP |
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Term
| How are chlamydia different from bacteria? |
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Definition
-intracellular
-cannot generate ATP (bacteria can)
-reproduce with 2 stage life cycle (bacteria use fission) |
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Term
| How are chlamydia different from viruses? |
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Definition
-have both DNA and RNA (viruses have either/or)
-reproduce with 2 stage life cycle (viruses are synthesized)
-sensitive to antibiotics (viruses are resistant) |
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Term
| What do chlamydia invade? |
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Definition
| epithelium, especially columnar epithelium (respiratory, conjunctivitis, endocervix) |
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Term
| What are example of destruction resulting from the inflammatory reaction caused by a chlamydia infection? |
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Definition
corneal scarring
fallopian tube obstruction |
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Term
| What type of genital infections is Chlamydia trachomatis responsible for? |
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Definition
cervicitis
nongonococcal urethritis
epididymitis |
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Term
| Who usually gets inclusion conjunctivitis as a result of a Chlamydia trachomatis infection? |
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Definition
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Term
| What conditions does Chalmydia trachomatis cause in infants? |
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Definition
inclusion conjunctivitis
infant pneumonia |
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Term
| What can significant fallopian tube scarring lead to? |
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Definition
infertility
ectopic tubal pregnancy
chronic pelvic pain (PID) |
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Term
| discharge typical of chlamydia infection |
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Definition
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Term
| Chlamydial pneumonia occurs _______ after birth. |
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Definition
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Term
| symptoms of chlamydial pneumonia |
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Definition
respiratory distress
rhinitis
cough
afebrile
feeding problems |
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Term
| An infant infected with chlamydial pneumonia will have... |
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Definition
| anti-chlamydial IgM antibodies |
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Term
| What is the most sexually transmitted disease in the US? |
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Definition
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Term
| Inclusion conjunctivitis presents ______ after birth. |
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Definition
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Term
| What is the diagnosis of inclusion conujunctivitis based on? |
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Definition
| demonstrating inclusion bodies in infected cells |
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Term
| What serotypes of Chlamydia trachomatis are responsible for genital infections, inclusion conjunctivitis, and infant pneumonia? |
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Definition
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Term
| What serotypes of Chlamydia trachomatis are responsible for blindness in Asia, Africa, and Native Americans? |
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Definition
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Term
| What is a major cause of preventable blindness in Asia, Africa, and Native Americans? |
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Definition
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Term
| What does trachoma cause? |
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Definition
inturned eyelashes
corneal scarring
eventual blindness |
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Term
| transmission of Chlamydia trachomatis responsible for trachoma |
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Definition
| hand to hand transfer of infected eye secretions or sharing contaminated clothing/towels |
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Term
| another name for trachoma |
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Definition
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Term
| What special type of testing can be done to detect chlamydia infections (as well as Neisseria gonorrheae)? |
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Definition
| direct immunofixation (DIF) antibody labeling |
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Term
| What bacteria causes lymphogranuloma venereum? |
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Definition
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Term
| What countries is lymphogranuloma venereum most prevalent in? |
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Definition
| Africa, Asia, South America |
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Term
| symptoms of lymphogranuloma venereum |
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Definition
painless papule/ulcer as primary lesion, fever, headache, myalgia
progresses to inflammation and swelling of lymph nodes and dissemination
late development of ulcers, fistula, and genital elephantiasis |
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Term
| What bacteria causes psittacosis? |
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Definition
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Term
| What chlamydial infection is found in pet birds, zoo birds, and turkey flocks and is transmitted to humans by exposure to an infected bird or dried bird excrements? |
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Definition
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Term
| clinical manifestations of Chlamydia psittaci infection |
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Definition
atypical pneumonia
headache, fever, macular rash, non-productive cough, rales, consolidation |
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Term
| How do you diagnose psittacosis? |
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Definition
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Term
| How is Chlamydia pneumoniae spread? |
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Definition
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Term
| clinical manifestations of Chlamydia pneumoniae |
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Definition
atypical pneumonia
without purulent productive cough, near normal lung exam, lung infiltrates on CXR
bronchitis, sinusitis |
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Term
| Chlamydia pneumoniae is/is not a sexually transmitted infection. |
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Definition
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Term
| How is a Chlamydia pneumoniae infection diagnosed? |
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Definition
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Term
| What is the most important thing to recognize about chlamydia? |
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Definition
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