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Chemotherapy
Study guide for verbal Chemo test
46
Nursing
Graduate
02/27/2016

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Cards

Term
What is the formula for calculating BSA?
Definition
height (cm) X weight (kg) divided by 3600 then get the square root of that number. Round to the hundreth
Term
What are the special instructions for donning gloves when giving chemo?
Definition
double glove: one under the chemo gown one over
Term
Give the normal lab values for the following labs. (Values for Children's Oncology)
WBC
Hgb
Hct
Platelets
Definition
WBC: 4.5 - 14.5 (thousand)
Hgb: 11.5 - 15.5
Hct: 35 - 45%
Platelets: 140-440 thousand
Term
What is a normal ANC?
What is considered severe neutropenia?
Definition
normal is >1500
severe neutropenia is <500
Term
How is ANC calculated?
Definition
add the percentage of segmented neutrophils (segs) to the percentage of immature neutrophils (bands) and multiply this by the WBC to the thousand
Term
Why does chemo cause bone marrow suppression?
Definition
chemo kills rapidly dividing cells like those produced in the bone marrow
Term
Bone marrow suppression can lead to any or all of what 3 conditions?
Definition
thrombocytopenia, anemia, leukopenia
Term
Define thrombocytopenia, anemia, leukopenia, and pancytopenia.
Definition
thrombocytopenia: low platelet count
anemia: low Hgb/Hct
leukopenia: low WBC
pancytopenia: depression of all 3 cell lines
Term
What are the nursing interventions for stomatitis?
Definition
-provide ALCHOHOL FREE mouth washes
-encourage a bland diet
-use toothettes
-pain meds
Term
What are the nursing interventions for neutropenia?
Definition
-GOOD HAND HYGEINE
-oral care
-avoid skin breakdown
-no sick visitors
-encourage good nutrition and rest
-VS q4 or more if needed
-notify for temp >101
-change IV tubing per protocol
-NO RECTAL TEMPS OR SUPPOSITORIES
-sterile prep for all procedures
(finger sticks, meds, tubing changes)
-avoid catheters
-dressing changes per protocol
Term
What are the nursing interventions for thrombocytopenia?
Definition
-no IM injections
-no aspirin or ibuprofen
-soft toothbrushes; no flossing
-apply pressure to venipuncture sites
-stool softeners
-no rectal temps or suppositories
-check stools for blood
-use electric razors
-observe for bruising
-avoid invasive procedures
-control menses
-do not dislodge clots
-no contact sports
Term
Adriamycin is also known as?
Definition
Doxorubicin
Term
How is Adriamycin administered?
Definition
IV infusion 30 min to 96 hrs via CVL or IVP
Term
What are the possible side effects of Adriamycin?
Definition
cardiotoxicity, vesicant, stomatitis, red/orange urine, hyperpigmentation of the nailbeds or skin creases, radiation recall
Term
What is the nursing care for Adriamycin?
Definition
infuse only through a CVL for IV infusions, check for blood return at the beginnning and end of infusion as well as q 2-4, check site q 1 for signs of infiltration, flush line until it is totally cleared following infusion, if loss of blood return stop infusion and evaluate
Term
How is Vincristine administered?
Definition
IVP push - check blood return before and after infusion
IV infusion - check blood return before and after infusion and q 2 during, only use CVL if unavailable MUST use a FRESH PIV
*LETHAL IF GIVEN INTRATHECALLY*
Term
What are the possible side effects of Vincristine?
Definition
soft tissue damage with extravastion, neurotoxicity (peripheral neuropathy, decreased DTRs, jaw pain, constipation), no myelosuppression or N/V, SIADH
Term
What is the nursing care for Viscristine?
Definition
Max dose 2mg, don't give more than once every 5 days
Term
How is Cytoxan administered?
Definition
PO, IV push or infusion
Term
What are the side effects of Cytoxan?
Definition
hemorrhagic cystitis, SIADH, metallic taste
Term
What is the nursing care for Cytoxan?
Definition
check urine for blood prior to each dose, use uro-protectant MESNA when ordered, maintain good hydration IV hydration is essential following high doses, have pt void regularly for 24 hours following dose, monitor serum Na
Term
How is Cis-Platinum administered?
Definition
IV infusion
Term
What are the possible side effects of Cis-Platinum?
Definition
nephrotoxicity, ototoxicity, electrolyte wasting, SIADH, severe N/V
Term
What is the nursing care for Cis-Platinum?
Definition
weigh at arrival and daily, strict I&O, monitor UOP, treat N/V prophylactically 30 mins prior to administration and q 4 prn
Term
How is Methotrexate administered?
Definition
IV,IM,PO,IT
Term
What are the possible side effects of Methotrexate?
Definition
renal impairment, stomatitis/mucositis, rashes, leukoencephalopathy, hepatotoxicity, photosensitivity
Term
What is the nursing care for Methotrexate?
Definition
administer leucovorin as ordered, draw Methotrexate levels, Bactrim should be held during and following administration, maintain hydration (check urine specific gravity q8, maintain alkaline urine (check urine pH each void), oral care
Term
How is Cytarabine administered?
Definition
IV push, IT, SQ, IV infusion
Term
What are the possible side effects of Cytarabine?
Definition
CNS toxicity, Ara-C Syndrome, fever, rash, conjunctivitis
Term
What is the nursing care with Cytarabine?
Definition
give steroid eye drops with high doses
Term
How is Etoposide administered?
Definition
IV infusion over at least 2 hrs, PO
Term
What are the possible side effects of Etoposide?
Definition
anaphylaxis, hypotesion with rapid infusion
Term
What is the nursing care for Etoposide?
Definition
dilute to 0.4mg/mL, Epi 1:1000 IM at bedside, VS q 15mins for first hr then q 30 mins for 2nd hr, premedicate with Benadryl for each dose, stop and notify for uritcaria/cough, stop and give epi for severe wheezing/SOB and notify
Term
How is Prednisone administered?
Definition
PO, IV
Term
What are the possible side effects of Prednisone?
Definition
increased appetite/weight gain, HTN, heart burn, mood swings, transient diabetes, oral candidasis
Term
What is the nursing care for Prednisone?
Definition
monitor BP at least q shift, no added salt diet, disguise taste, monitor glucose, must be taken even if vomiting
Term
How is L-Asparaginase administered?
Definition
IM, IV
Term
What are the possible side effects of L-Asparaginase?
Definition
anaphylaxis, hypersensitivity reactions, transient diabetes, pancreatitis, no myelosuppression or N/V, coag abnormalities
Term
What is the nursing care for L-Asparaginase?
Definition
must have access to give meds/bolus in event of anaphylaxis, epi 1:1000 IM at beside, 0.01mg/kg to a max of 0.5mg, monitor for allergic reaction for 1-2 hrs after administering, give epi for anaphylaxis
Term
How is Ifosfamide administered?
Definition
IV infusion
Term
What are the possible side effects of Ifosfamide?
Definition
hemorrhagic cystitis, renal tubular damage, CNS toxicity, SIADH, hyponatremia
Term
What is the nursing care for Ifosfamide?
Definition
check urine for blood before administering, always give MESNA with Ifosfamide, monitor serum Na, notify for any neuro changes
Term
How is Carboplatin administered?
Definition
IV infusion
Term
What are the possible side effects of Carboplatin?
Definition
myelosuppression esp thrombocytopenia, renal toxicity
Term
How is Topotecan administered?
Definition
IV infusion
Term
What are the possible side effects of Topotecan?
Definition
fever, flu-like symptoms, diarrhea
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