Shared Flashcard Set

Details

Chemistry- tumor markers
test 3
26
Medical
Undergraduate 4
10/13/2009

Additional Medical Flashcards

 


 

Cards

Term
what are the four stages of cancer?
Definition
induction, in situ, invasion, dissemination
Term
Which phase of cancer does the transformed cell develop into a cancer?
Definition
in situ phase
Term
What are the 4 ways that lab tests can serve concerning tumors?
Definition
detection or screening, confirmation, classification/staging, monitoring
Term
What is the most important function of tests in cancer?
Definition
monitoring the desease or its response to therapy
Term
What tumor marker is an enzyme that is specific for prostate tissue and is elevated in carcinoma, inflammation, and benign prostatic hypertrophy?
Definition
PSA- prostate-specific antigen
Term
A low free PSA indicates what in terms of cancer risk?
Definition
low PSA indicates greater possibility of developing cancer
Term
What tumor marker is used for liver and bone?
Definition
alkaline phosphatase
Term
What tumor marker is used for pancreatic?
Definition
amylase
Term
What tumor marker is approved for diagnosis of primary hepatocellular carcinoma or nonseminomatous testicular cancer?
Definition
alphafetoprotein
Term
What non-cancerous conditions can cause an increase in alphafetoprotein?
Definition
cirrhosis, hepatitis, CMV infections, chronic hepatic conditions
Term
what tumor marker is used to assess prognosis and recurrence of colon cancer?
Definition
carcinoembryonic antigen
Term
Which tumor marker has 2 reference ranges- one for smokers and one for nonsmokers?
Definition
carcinoembryonic antigen
Term
Which tumor marker is used to monitor theraphy and disease progression in metastatic breast cancer?
Definition
CA 15.3 and CA 27.29
Term
Which tumor marker is used to predict patient's response to Herceptin treatment?
Definition
Her2/neu
Term
What cancer is monitored with CA 125?
Definition
ovarian cancer
Term
What two receptor-site proteins are measured by tissue biopsy and are used together to predict patient's response to antihormonal therapy in breast cancer patients?
Definition
Estrogen receptor and Progesterone receptor
Term
What gland secretes calcitonin?
Definition
thyroid gland
Term
What cancer causes elevated levels of calcitonin?
Definition
medullary carcinoma of the thyroid
Term
What virus is associated with genital cancer and benign genital warts?
Definition
Human papilloma virus
Term
What oncogene is associated with B and T cell lymphoma, small cell lung cancer, sarcoma, and endotheliomas?
Definition
N-myc
Term
Is p53 an oncogene or a supressor gene?
Definition
suppressor
Term
What 3 cancers are associated with p53 mutations?
Definition
colon, breast, ovaries
Term
what cancer is associated with philadelphia chromosome?
Definition
chronic myelogenous leukemia
Term
What genetic marker is associated with hereditary breast and ovarian cancers?
Definition
BRCA1 and BRCA2
Term
What chromosome is BRCA1 located on?
Definition
chromosome 17
Term
What chromosome is BRCA2 located on?
Definition
chromosome 13
Supporting users have an ad free experience!