Term
| Define International Unit of Enzyme Activity |
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Definition
| Amount of Enzyme that produces 1 umol of product/minute under standardized conditions |
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Term
| Given the same reaction time, what effect will a 10 degree rise in temperature have on enzymatic test results? |
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Definition
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Term
True or False:
Temperature too HIGH will cause enzymes to denature |
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Definition
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Term
True or False:
Temperature too LOW will stop the reaction |
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Definition
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Term
| Given the same reaction time, what effect will a 10 degree drop in temperature have on enzymatic test results? |
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Definition
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Term
| What is meant by zero order kinetics? |
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Definition
| Substrate is provided in excess |
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Term
| What is the final reaction product of zero order kinetics dependent on? |
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Definition
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Term
| Which enzymes will be falsely elevated if a sample is hemolyzed? |
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Definition
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Term
| In which enzyme test may hemolysis interfere to cause a falsely DECREASED result? |
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Definition
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Term
What Enzyme OR PANEL of Enzymes is commonly used to evaluate the following:
Liver Function |
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Definition
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Term
What Enzyme OR PANEL of Enzymes is commonly used to evaluate the following:
Cardiac Function |
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Definition
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Term
What Enzyme OR PANEL of Enzymes is commonly used to evaluate the following:
Pancreatitis |
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Definition
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Term
What Enzyme OR PANEL of Enzymes is commonly used to evaluate the following:
Skeletal Muscle Injury/Disease |
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Definition
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Term
What Enzyme OR PANEL of Enzymes is commonly used to evaluate the following:
Biliary Obstruction |
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Definition
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Term
What Enzyme OR PANEL of Enzymes is commonly used to evaluate the following:
Bone Disease |
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Definition
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Term
What Enzyme OR PANEL of Enzymes is commonly used to evaluate the following:
Organophosphate Poisoning |
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Definition
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Term
| What enzyme is the MOST SENSITIVE indicator of Alcohol Ingestion |
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Definition
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Term
| If a GGT is Normal, and the ALP is Increased, what is the probably organ source? |
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Definition
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Term
| If a ALT is Normal, and the AST is Increased, what is the probably organ source? |
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Definition
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Term
| In which Disease are the HIGHEST Levels of AST/ALT Seen? |
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Definition
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Term
| AMI, Liver Disease, Pulmonary Infarction, and Pernicious Anemia will all cause an INCREASE in Which Enzyme? |
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Definition
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Term
| Why must a patient's age be considered when interpreting ALP results? |
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Definition
| Adolescents have INCREASED levels due to NORMAL Bone Growth |
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Term
| In what other "normal" condition is an ELEVATED ALP Observed? |
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Definition
Pregnancy
- produced by the placenta |
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Term
| What is the clinical usefulness for running an Ostase test? |
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Definition
Bone specific;
Determines response to therapy for osteoporosis in post-menopausal women |
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Term
| What specific assay has REPLACED the ACP for evaluation of possible PROSTATE carcinoma? |
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Definition
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Term
| What legal significance might an ACP level have if detected on a vaginal swab? |
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Definition
| Positive Result is indicative of the presence of seminal fluid |
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Term
| If a specimen for LD cannot be analyzed right away, Why should it NOT be stored in the Fridge? |
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Definition
It is Cold Labile;
Causes a False Decreased Value |
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Term
| List the order of appearance of Cardiac Markers following an AMI |
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Definition
1. Myoglobin
2. Troponin I / CKMB
3. Troponin T |
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Term
| Which cardiac marker is MOST SPECIFIC for Cardiac Tissue? |
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Definition
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Term
| Which cardiac marker is also Markedly Elevated in cases of Skeletal Muscle Trauma? |
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Definition
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Term
| What is the formula for the CK Relative Index? |
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Definition
| (CKMB x 100) / (Total CK) |
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Term
| What info does the CK-Relative Index provide? |
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Definition
| Differentiates CKMB from heart vs CKMB from Muscle |
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Term
| Which cardiac marker is used to diagnose / monitor congestive heart failure? |
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Definition
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Term
| In regards to cardiac testing, what is the purpose of performing hsCRP? |
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Definition
| To predict future coronary events |
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Term
| What is the purpose of measuring N-telopeptide? |
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Definition
| Indicator of bone resorption |
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