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Lowers surface tension, make microbes accessible to other agents |
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High concentration:Dissolve lipids, disrupt membranes, denature proteins, inactivate enzymes Low concentration: Wetting agent |
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Lower pH and denature proteins |
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Raise pH and denature proteins |
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Oxidize cell components in absence of organic matter |
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Denature proteins when mixed with water |
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Disrupt membranes, denature proteins, inactivate enzymes; not impaired by organic matter |
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Disrupt structure of proteins and nucleic acids |
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May interfere with replication or block cell wall synthesis |
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Use of soaps and detergents? |
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Definition
Hand washing, laundering, sanitizing kitchen and dairy equiptment |
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Definition
Cationic detergents: sanitize utensils Anionic detergents: launder clothes and clean household objects Quaternary ammonium compounds: antiseptics on skin |
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Silver nitrate used to prevent gonococcal infections Mercury compounds to disinfect skin and inanimate objects Copper to inhibit algal growth Selenium to inhibit fungal growth |
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Definition
Chorine used to kill pathogens in water and to disinfect utensils Iodine used as skin antiseptics |
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Definition
Isopropyl alcohol used to disinfect skin Propylene glycol used in aerosols |
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Phenol: Disinfect surfaces and destroy discarded cultures Amylphenol: destroys vegetative organisms and inactivates viruses on skin and inanimate objects Chlorhexidine gluconate: surgical scrub |
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Hydrogen peroxide used to clean puncture wounds Potassium permanganate to disinfect instruments |
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Use of alkylating agents? |
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Definition
Formaldehyde: inactivates viruses without destroying antigenic properties Glutaraldehyde: sterilize equiptment Betapropiolactone: destroy hepatitis viruses Ethylene oxide: sterilize inanimate objects that would be harmed by high temperatures |
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Acridine: used to clean wounds Crystal Violet: treat some protozoan and fungal infections |
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