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Chapters 3 + 4
Cell parts, DNA replication, etc.
70
Biology
Undergraduate 1
02/23/2014

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Term
How many cells are in the human body?
Definition
75 trillion cells
Term
How many millimeters is one micrometer?
Definition
One thousandth of a millimeter
Term
What is differientiation?
Definition
When cells specialize
Term
What is a composite cell?
Definition
Typical body cell
Term
What are the 3 major parts of a cell?
Definition
  1. nucleus
  2. cytoplasm
  3. cell membrane
Term
What is the cell membrane?
Definition
Outer limits of a cell; they control what moves in and out of a cell
Term
What is water-soluble?
Definition
"heads" for surfaces (hydrophilic)
Term
What is water-insoluble?
Definition
"tails" from interior (hydrophibic)
Term
What is the function of cholersterol?
Definition
Stabilizes the membrane and help to make it impermeable to water
Term
What does selectin do?
Definition
Allows white blood cells to "anchor"
Term
What does integrin do?
Definition
Guides white blood cells through capillary walls; important for growth of embryonic tissue and nerve cells
Term
What is cytoplasm?
Definition
Networks of membranes and organelles; suspended in the cytosol
Term
What are ribosomes?
Definition
Free floating or connected to ER; provides structural support and enzyme activity to amino acids to form protein
Term
What is ER?
Definition
Connected, membrane bound sacs, canals, and vesicles; transport system
Term
What is the golgi apparatus?
Definition
Stack of flattened sacs; modifies, packages and delivers proteins
Term
What are vesicles?
Definition
Membraneous sacs; stores substances
Term
What is the mitochondria?
Definition
Membraneous sac, inner membrane, outer membrane, cristae; generate energy (ATP) "power house"
Term
What are lysosomes?
Definition
Enzyme containing sacs
Term
What are centrosomes?
Definition
Two rod-like centrioles; used to provide cilia and flagella; distributes chromosomes during cell division
Term
What are peroxisomes?
Definition
Enzyme containing sacs; break down organic molecules
Term
What is cilia?
Definition
Short hair like projections; propel substances on cell surface
Term
What is flagellum?
Definition
Long tail-like projections; provides mobility to sperm.
Term
What are microfilaments and microtubules?
Definition
Thin rods and tubules; support cytoplasm; allows for movement of organelles
Term
What is the nucleolus?
Definition
Dense collection of RNA and proteins; site of ribosome production
Term
What is the cell nucleus?
Definition
Control center of the cell
Term
What is chromatin?
Definition
Consists of all the cell's chromosomes, each containing DNA wound around proteins; stores information for synthesis of proteins
Term
What is osmosis?
Definition
(water molecules) momvement of water molecules causes osmotic pressure
Term
What is hemolysis?
Definition
When red blood cells burst
Term
What is filtration?
Definition
When molecules move through membranes by diffusion because of their random movements
Term
Phases of Interphase
Definition
  • G1 - growth
  • S- DNA replication
  • G2- growth
Term
What is cytokinesis?
Definition
Division of cytoplasm
Term
What cell cycle does cell division start in?
Definition
Anaphase
Term
What are telomeres?
Definition

Mitotic clock

DNA at the tips of the chromosomes

Term
Apoptosis
Definition
Form of cell death
Term
Anabolism
Definition

Larger molecules are made from smaller ones

Requires energy

Provides the materials needed for cellular growth and repair

Term
Catabolism
Definition

Larger molecules are broken down into smaller ones

Releases energy

Breaks down larger molecules into smaller ones

Term
Metabolic Reation
Definition
Includes hundreds of very specific chemical changes that must occur in particular sequences
Term
Enzymes
Definition

Control rates of metabolic reactions

Lower activation energy needed to start reactions

Most are globular proteins with specific shapes 

Not consumed in chemical reactions

Term
Energy
Definition
The capacity to change something; it is the ability to do work
Term
Forms of energy:
Definition
  • heat
  • light
  • sound
  • electrical energy
  • chemical energy
  • mechanical energy
Term
ATP
Definition
carries energy in a form that the cell can use
Term
3 parts of ATP:
Definition
  1. adenine molecule
  2. ribose molecule
  3. three phosphate molecules in a chain
Term
Oxidation
Definition
Burning glucose
Term
Cellular Respiration happens in these 3 parts:
Definition
  1. Glycolysis
  2. Citric Acid cycle
  3. Electron Transport Chain
Term
What does cellular respiration produce?
Definition
  • carbon dioxide
  • water
  • ATP (chemical energy)
  • heat
Term
What are anaerobic reactions?
Definition
reactions without O2 - produce little ATP
Term
What are aerobic reactions?
Definition
with O2 - produce most ATP
Term
Gycolysis
Definition

series of 10 reactions

breaks down glucose into 2 pyruvic acids and molecules

occurs in cytoplasm

anaerobic phase of cellular respiration

yields 2 ATP molecules per glucose molecule

Term
What is excess glucose stored as?
Definition

Glycogen 

Fat

Lipids and proteins

Term
Genetic Information
Definition
Instructions for the cell on how to make our proteins
Term
Gene
Definition
Section of our DNA that contains the complete information for making a particular protein
Term
Genetic Code
Definition
The correspondance between a unit of DNA information and a particular amino acid
Term
Structure of DNA
Definition
Made of 2 stands of nucleotides which spiral
Term

DNA Replication

 

Definition

Hydrogen bonds break between bases 

Double stands unwind and pull apart

New nucleotides pair with exposed bases

Controlled by DNA polymerase

Term
Helicase
Definition
Enzyme that starts replication process
Term
SSBP
Definition
holds the DNA open
Term
DNA Polymerase III
Definition
binds to leading strand
Term
RNA Primer
Definition
starting location
Term
DNA Polymerase I
Definition
replaces the RNA with DNA
Term
Okazaki Fragment
Definition
Fragments of DNA that are laid down on lagging strand
Term
Ligase
Definition
Binds the Okazaki fragments together
Term
How much percent does the human genome differ from person to person?
Definition
1/10 of one percent
Term
Mutations
Definition

Changes in genetic information

Result when:
Extra bases are added or deleted

Bases are changed

May or may not change the protein 

Term
Inborn errors of Metabolism
Definition
occurs from inheriting a mutation that then alters an enzyme
Term
Metabolic Pathways
Definition
Series of enzyme-controlled reactions leading to formation of a product
Term
Enzyme names commonly:
Definition

reflect the substrate

have the suffix -ase

ex: sucrase, protease, lipase

Term
Cofactors
Definition
Make some enzymes active
Term
Coenzymes
Definition

Organic molecules that act as cofactors

Vitamins

Term
Factors that alter enzymes:
Definition
  • Heat
  • Radiation
  • Electricity
  • Chemicals
  • pH changes
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