Term
Drug of choice for most UTIs ?
When should it not be used? |
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Definition
Most UTIs - SMX/TMP
Do not use it in case of sulfa allergy |
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Term
Empiric treatment of uncomplicated UTIs
1st line
2nd line
When should treatment Bactrim last 1 week? |
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Definition
Empiric treatment of uncomplicated UTIs
1st line - SMX/TMP 3 days, TMP 3 days, or Nitrofurantoin 5 days
2nd line - FQs 7 days, cephalexin 7 days.
Bactrim treatment should last 7 days in women with symptoms lasting over a week, or recurrent UTI in last month |
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Term
Empiric treatment of UTIs with pyelonephritis
1st line moderate , severe |
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Definition
Empiric treatment of UTIs with pyelonephritis
1st line - FQs 7-14 days moderate, Aminoglycosde + if enterococcus add ampicillin. |
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Term
Empiric treatment of Complicated UTIs
Moderate
Severe |
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Definition
Empiric treatment of Complicated UTIs
Moderate: 7-10 day treatment with either SMX/TMP, FQs, Nitrofurantoin, TMP
Severe: Aminoglycosides with ampicillin if enterococcus for 10-14 days |
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Term
Empiric treatment of UTIs with prostatitis
Acute
Chronic |
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Definition
Empiric treatment of UTIs with prostatitis
Acute - Aminoglycoside with cloxacillin if S. aureus, or with ampicillin if enterococcus
Chronic - FQs 4-6 weeks! |
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Term
Which FQs can be used in UTIs? |
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Definition
CLON
Cipro, levo, oflo, nor |
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Term
Pregnancy w UTI - Asymptomatic bacteriuria and symptomatic cystitis
treatment?
What is teratogenic? which trimester
Preferred therapy in pyelonephritis & pregnancy? |
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Definition
3-7 day treatment amoxicillin, nitrofurantoin, amox/clav, cephalexin
SMX/TMP, or TMP are teratogenic 1st trimester.
Avoid FQs in pregnancy.
Preferred therapy in pyelonephritis & pregnancy is ceftriaxone |
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Term
Which UTI Abxs can be used in breastfeeding? |
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Definition
Breastfeeding - FQs, amoxicillin, nitrofurantoin, amoxicillin, and cephalosporins, SMX/TMP
NOT aminoglycosides. |
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Term
Prevention of UTIs in pregnant women preferred agents |
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Definition
Preferred agents - Nitrofurantoin or cephalexin |
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Term
UTIs
Contraindications in SMX ?
Contraindication in Nitrofurantoin? |
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Definition
SMX - sulfa allergy
Nitrofurantoin - CrCl < 60, OR pyenonephritis |
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