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Chapter 9
biology for a changing world second edition
18
Biology
Undergraduate 1
10/30/2014

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Term
Cancer
Definition
a disease of unregulated cell division; cells divide inappropriately and accumulate, in some instances forming a tumor
Term
Chemotherapy
Definition
The treatment of disease, specifically cancer, by the use of chemicals.
Term
Cell Division
Definition
The process by which a cell reproduces itself; cell division is important for normal growth, development, and repair of an organism.
Term
Cell Cycle
Definition
The ordered sequence of stages that a cell progresses through in order to divide during its life; stages include preparatory phases (G, S, G2) and division phases (Mitosis and cytokinesis)
Term
Interphase
Definition
The stage of the cell cycle in which cells spend most of their time. preparing for cell dicision. There are three distinct sub-phases; G1, S, and G2
Term
Mitosis
Definition
The segregation and separation of duplicated chromosomes during cell division
Term
Cytokinesis
Definition
The physical divivsion of a cell into two daughter cells
Term
Sister Chromatids
Definition
The two identical DNA molecules that make up a duplicated chromosome following DNA replication.
Term
Centromere
Definition
The specialized region of a chromosome where the sister chromatids are joined; critical for proper alignment and separation of sister chromatids during mitosis.
Term
Microtubules
Definition
Hollow protein fibers that are key components of the cytoskeleton and make up the fibers of the mitotic spindle.
Term
Mitotic Spindle
Definition
The structure that separates sister chromatids during mitosis.
Term
Kinetochore
Definition
Proteins located at the centomere that provide an attachment point for microtubules of the mitotic spindle.
Term
Mutation
Definition
A change in the nucleotide sequence of DNA
Term
Cell Cycle Checkpoint
Definition
A cellular mechanism that ensures that each stage of the cell cycle is completed accurately.
Term
Apoptosis
Definition
Programmed cell death; often referred to as cellular suicide.
Term
Tumor
Definition
A mass of cells resulting from uncontrolled cell division.
Term
Metastasis
Definition
The spread of cancer cells from one location in the body to another.
Term
Radiation Therapy
Definition
The use of ionizing (high-energy) radiation to treat cancer.
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