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Chapter 9-11 Test
DNA, Protein Synthesis, & Genetic Engineering
48
Biology
10th Grade
04/12/2010

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Term
tried to make vaccine for pneumonia. worked with mice. discovered transformation. (1928)
Definition
Griffith
Term
stated DNA is transferred in transformation. most scientists skeptical. (1944)
Definition
Avery
Term
studied bacteriophage. proved that DNA, not protein, is genetic material. (1952)
Definition
Hershey & Chase
Term
discovered equal amounts of nucleotides (A,C,T,G) in DNA.
Definition
Chargaff
Term
saw DNA's shape using x-ray diffraction photo. (1952)
Definition
Wilkins & Franklin
Term
published first to describe DNA twisted ladder shape. "double helix." came up with terms for nucleotides, (purines & pyrimadines). (1953)
Definition
Watson & Crick
Term
base-pairing
Definition
A=T C=G
Term
virulent
Definition
able to cause disease
Term
bacteriophage
Definition
virus that infects bacteria
Term
bad attacks good & good becomes bad.
Definition
transformation
Term
nucleotides
Definition
subunits of DNA
Term
double helix
Definition
"twisted ladder" shape of DNA
Term
mutation
Definition
change in a gene
Term
deoxyribose
Definition
5-carbon sugar in DNA
Term
purines
Definition
A & G
Term
pyramidines
Definition
C & G
Term
DNA helicase
Definition
open up the double helix by breaking hydrogen bonds
Term
replication fork
Definition
two areas where the double helix seperates.
Term
DNA polymerase
Definition
adds new nucleotides to the exposed nitrogen bases
Term
leading strand
Definition
follows the helicase
Term
lagging strand
Definition
moves away from helicase
Term
okazaki fragments
Definition
fragments on lagging strand that are bound by DNA ligase
Term
what is DNA replication?
Definition
how DNA copies itself
Term
when does DNA replication occur?
Definition
interphase
Term
mRNA
Definition
messenger RNA
Term
tRNA
Definition
transfer RNA
Term
rRNA
Definition
ribosomal RNA
Term
carries sequences of nucleotides that code for protein from nucleus to ribosomes.
Definition
mRNA
Term
picks up individual amino acids in cytoplasm and carries them to ribosomes.
Definition
tRNA
Term
joins amino acids
Definition
rRNA
Term
codon
Definition
sequence of 3 bases in mRNA that codes for a specific amino acid.
Term
anti-codon
Definition
sequence of three bases on tRNA
Term
transferring a gene's instructions for making a protein to an RNA molecule
Definition
transcription
Term
reading instructions on an RNA molecule to put together the amino acids that make up a protein
Definition
translation
Term
biotechnology
Definition
involves manipulation of genetic information.
Term
production of organisms with new genetic traits
Definition
genetic engineering
Term
DNA is taken from one organism and spliced into the DNA of another. the new combined DNA is called ____________ ___.
Definition
recombinant DNA
Term
DNA is in the form of a ring called a _______.
Definition
plasmid
Term
cloning
Definition
production of a complete organism from a somatic cell
Term
restriction enzyme
Definition
recognize specific short sequences of DNA, then cut the DNA at specific sites within the sequences.
Term
an agent that is used to carry the gene of interest into another cell
Definition
vector
Term
piece of DNA that overlaps the promoter site and serves as the on-off switch is called an ________.
Definition
operator
Term
group of genes that codes for enzymes involved in the same function, their promotor site, and the operator all function together as an ______.
Definition
operon
Term
operon that controls the metabolism of lactose
Definition
lac operon
Term
protein that binds to an operator and blocks RNA polymerase from binding to a promoter site
Definition
repressor
Term
three genes are located next to each other, and all are conrolled by the same ________ site.
Definition
promoter
Term
transgenic animal
Definition
animal that has foreign DNA in its cell
Term
transformation is prevented by.. ?
Definition
DNA destroying enzymes
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