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Chapter 8--Membrane Structure and Function
AP Biology Chapter 8 notes.
58
Biology
11th Grade
10/09/2013

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Term
Plasma Membrane
Definition
separates living cell from its nonliving surroundings; selectively permeable; thin barrier 8 cm thick controls traffic into and out of cell.
Term
Main Macromolecules
Definition
lipids, proteins, and some carbohydrates
Term
Most Abundant Lipids
Definition
phospholipids
Term
Fluid Mosaic Model
Definition
*look up diagram
proteins embedded in double layer of phospholipids
Term
Garter-Grendel Model
Definition
1925 Garter & Grendel reasoned that cell membranes must be a phospholipid bilayer, 2 molecules thick.
Term
Phospholipid Bilayer
Definition
2 layers of phospholipids; hydrophobic tails pointing inwards while polar head is projecting outward.
Term
Davson-Danieli Model
Definition
phospholipid bilyaer between 2 layers of globular proteins.
Term
Present Model
Definition
Singer & Nicholson; hydrophilic regions of proteins and p.lipids are in max. contact w/ water and the hydrophobic regions are in non-aqueous envrmnt.
Term
Membrane Molecules
Definition
held in place by relatively weak hydrophobic interactions
Term
Membrane
Definition
collage of different proteins embedded in the fluid matrix of the lipid bilayer.
Term
Peripheral Proteins
Definition
not embedded in the lipid bilayer at all.
Term
Integral Proteins
Definition
Penetrate the hydrophobic core of the lipid bilayer, often completely spanning the membrane.
Term
Functions of Proteins
Definition
transport, enzymatic activity, signal transduction, intercellular joining, cell-cell recognition, attachment to cytoskeleton & extracellular matrix
Term
Cell-Cell Recognition
Definition
ability of cells to distinguish one type of neighboring cell from another; basis for rejections of foreign cells by immune system.
Term
How do Cells Recognize Other Cells?
Definition
keying on surface molecules, often carbohydrates, on the plasma membrane
Term
Membrane Carbohydrates
Definition
usually branched ogliosaccharides with fewer that 15 sugar units; may form glycolipids or glycoproteins
Term
4 human blood groups
Definition
differ in the external carbohydrates on red blood cells
Term
Ogliosaccharides
Definition
on the external side of the p. membrane vary from species to species, individual to individual, even from cell type to cell type within the same individual
Term
A steady traffic of small molecules and ions move across the plasma membrane in both directions
Definition
..
Term
Sugars, amino acids, and other nutrients...
Definition
...enter a muscle cell and metabolic waste products leave.
Term
Cell
Definition
absorbs oxygen and expels CO2
Term
Cell (cont)
Definition
regulates concentrations of inorganic acids
Term
Specific ions and polar molecules on can cross the lipid bilayer by passing through transport proteins that span the membrane
Definition
...
Term
Some transport proteins have...
Definition
...hydrophilic channel that certain molecules or ions can use as a tunnel through the membrane.
Term
Passive Transport
Definition
no energy required
Term
diffusion across a membrane
Definition
passive transport
Term
Diffusion
Definition
driven by the intrinsic kinetic energy (thermal motion of heat) of molecules; random movements.
Term
Concentration Gradient
Definition
decreases free energy and increases entropy (randomness) by creating a randomized mixture
Term
Osmosis
Definition
passive transport (no energy required) of water; diffusion of water across a selectively permeable membrane
Term
Differences in the Relative concentration of dissolved materials in 2 solutions can...
Definition
lead to the movement of ions from one to the other
Term
Solution w/ Higher Concentration of Solutes
Definition
hypertonic
Term
Solution w/ Lower Concentration of Solutes
Definition
hypotonic
Term
Solutions w/ Equal concentration of solutes
Definition
isotonic
Term
Isotonic
Definition
movement of water out of the cell is exactly balanced by movement of water into the cell
Term
Hypotonic
Definition
he total molar concentration of all dissolved solute particles is less than that of another solution or less than that of a cell.
Term
Hypertonic
Definition
total molar concentration of all dissolved solute particles is greater than that of another solution, or greater than the concentration in a cell.
Term
Unbound water molecules
Definition
will move from the hypotonic solution where are abundant to the hypertonic solution where they are rarer
Term
Cell Survival
Definition
depends on balancing water uptake and loss
Term
animal cell immersed in an isotonic envrmt
Definition
experiences no net movement of water across its p. membrane
Term
cell in hypertonic envrmt
Definition
lose water, shrivel, and probably die
Term
cell in hypotonic envrmt
Definition
gain water, swell, burst
Term
cells with cell walls
Definition
plants, prokaryotes (lack nucleus), fungi, some protists
Term
aquaporins
Definition
water channel proteins; facilitate massive amount of diffusion
Term
gated channels
Definition
open or close depending on presence or absence of a physical or chemical stimulus
Term
chemical stimulus
Definition
usually different from the transported molecule
Term
active transport
Definition
pumping of solutes against gradients
Term
carrier assisted transport
Definition
some integral proteins act as carriers ferrying back and forth any molecules that can't readily diffuse due to size or polarity
Term
exocytosis
Definition
transport vesicle budded from the Golgi apparatus is moved by the cytoskeleton to the plasma membrane
Term
endocytosis
Definition
reversal of exocytosis; cell bringing in macromolecules by forming vesicles
Term
phagocytosis
Definition
cellular eating; cell engulfs particle by extending psuedopadia around it and packaging it in large vacuole
Term
pinocytosis
Definition
cellular drinking; cell creates vesicle around drop of extracellular fluid
Term
receptor
Definition
mediated endocytosis is very specific in what substances are being transported; triggered wen extrac. substances bind to special receptors, lighons
Term
water potential formula
Definition
(trident)(S)=-iCRT
Term
water potential
Definition
The measure of the relative tendency of water to move from one area to another, Water potential is caused by osmosis, gravity, mechanical pressure, or matrix effects including surface tension. It is useful in understanding water movements within plants, animals, and soil.
Term
pinocytosis
Definition
cellular drinking; cell creates vesicle around drop of extracellular fluid
Term
receptor
Definition
mediated endocytosis is very specific in what substances are being transported; triggered wen extrac. substances bind to special receptors, lighons
Term
water potential formula
Definition
(trident)(S)=-iCRT
Term
water potential
Definition
The measure of the relative tendency of water to move from one area to another, Water potential is caused by osmosis, gravity, mechanical pressure, or matrix effects including surface tension. It is useful in understanding water movements within plants, animals, and soil.
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