Term
| What are CNS Deppressants? and what do they do? |
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Definition
- Antianxiety (anxiolytic) and sedatives are to help promote relaxations
- hypnotics help promote sleep
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Term
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Definition
- d/o that can be made up of nervousness, tension, worry, or other terms that denote an unpleasant feeling
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Term
| What is the pathology of anxiety? |
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Definition
- can be imbalances in neurotransmission systems
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Term
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Definition
| recurrent period of decreased mental and physical activity during which a person is relatively unresponsive to sensory and environmental stimuli |
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Term
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Definition
| prolonged difficulty going to sleep or staying asleep long enough to feel rested |
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Term
| what are Benzodiazepines used for? |
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Definition
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Term
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Definition
| Schedule IV drugs; have high potential for abuse and dependency |
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Term
| How do Benzodiazepines work? |
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Definition
- work by forming complex with benzodiazepine recetors and GABA in verve cells
- GABA binds to receptor complex Cl- ions enter cell and hyperpolarize cell, makes cell more stable and less responsive to excitatory neurotransmitters
- Benzos bind to receptor site and enhance inhibitory effect of GABA
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Term
| What are the pharmacokinetics of Benzodiazepines and how do they enter the body (route)? |
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Definition
- highly lipid soluble, makes it easy to enter CNS and perform action
- well absorbed with oral administration
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Term
| What are indications to use Benzodiazepines? |
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Definition
| antiznxiety, hypnotic, anticovulsant agents |
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Term
| what are contrindcations to using Benzodiazepines? |
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Definition
| severe respiratory disorders, severe liver or kidney disease, hypersentivity reactions, hx of ETOH or other drug abuse |
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Term
| Name all the Benzodiazephines |
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Definition
- diazepam (Valium)-prototype
- alprazolam (Xanax)
- lorazepam (Ativan)
- clonazepam (Klonopin)
- midazolam (Versed)
- temazepam (Restoril)
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Term
| What are sedative-hypnotic agents? |
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Definition
- chloral hydrate
- eszopiclone (Lunesta)
- ramelteon (Rozerem)
- zolpidem (Ambien)
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Term
| What does eszopiclone do? |
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Definition
| 1st hypnotic for long term use |
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Term
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Definition
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Term
| What is a type of herbal supplement? |
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Definition
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Term
| What do we know about melatonin |
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Definition
-don't really known how much we should take
- not standardized dose in a package |
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