Shared Flashcard Set

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Chapter 8
PowerPoint
32
Microbiology
Undergraduate 1
11/15/2010

Additional Microbiology Flashcards

 


 

Cards

Term
Rosalind Franklin and James Waston with Francis Crick
Definition
Who is responsible for the structure of DNA?
Term
within the nucleoid
Definition
Where is Bacterial and Archaeal DNA organized?
Term
the DNA exists as a single, circular chromosome
Definition
How does DNA exist within the nucleoid?
Term
DNA
Definition
What is highly compacted within a chromosome?
Term
Plasmids
Definition
Many microbial cells contain these that carry nonessential but often useful information
Term
1.) Inititation
2.) Elongation
3.) Termination
4.) Leading strand and lagging strand
Definition
Name the different parts of the highly regulated DNA replication process?
Term
Central Dogma
Definition
identifies the flow of genetic material (DNA -> RNA -> protein)
Term
Transcription
Definition
copies genetic information into RNA
Term
messenger RNA (mRNA)
transfer RNA (tRNA)
ribosome RNA (rRNA)
Definition
Name the different types of RNA
Term
Transcription
Definition
DNA serves as a template for new mRNA molecules
Term
Codon
Definition
The genetic code consisting of 3 letter words
Term
Codon
Definition
This can specify more than on specific amino acid
Term
Translation
Definition
the process of making the polypeptide at the ribosome
Term
1.) Chain Initiation
2.) Chain Elongation
3.) Chain Termination/Release
Definition
Name the Different Stages of Translation
Term
Protein Synthesis
Definition
Many antibiotics interfere with this, and it can be controlled in several ways
Term
They are compartmentalized within prokaryotic cells
Definition
Where does Transcription and Translation take place?
Term
Mutation
Definition
permanent changes in the DNA, can be spontaneous or induced, physical or chemical, and it can be heritable
Term
Spontaneous Mutation
Definition
A mutation that occurs naturally
Term
Induced Mutation
Definition
A mutation that is synthesized within a laboratory
Term
Chemical Mutagens
Definition
nitrous acid is an example because it causes an altered sequence in DNA
Term
Physical Mutation
Definition
an example is UV light because it causes thymine dimers that cause DNA strands to bulk out or express genes or synthesize proteins
Term
Point Mutation
Definition
silent base pair substitution that does not result in change in base and amino acid sequences because of multiple codons can be redundant so that it does not change
Term
Missense Mutation
Definition
there is base pair substitutions or deletion and it changes the amino acid sequences, which shifts everything making different codons
Term
Nonsense Mutation
Definition
base pair deletion or insertion of seqeuences and introduces a stop codon to stop the process
Term
Repair Mechanisms
Definition
attempt to correct mistakes or damage in the DNA because cells have the ability to repair damaged DNA
Term
Mismatch Repair
Excision Repair
Definition
Name Two types of Repair Mechanisms
Term
Mismatch Repair
Definition
when nucleotides do not match they get cut out so that the right pair can be added
Term
Excision Repair
Definition
the enzyme nuclease, cuts out the entire sequence that is mutated, by a thymine dimer e.g., and DNA polymerase fixes the strand that was cut out
Term
Transposable
Definition
These genetic elements can cause mutations
Term
Transposons
Definition
Barbara McClintock discovered these in maize
Term
Transposons and Insertion Sequences
Definition
these move from one DNA location to another
Term
Transposons
Definition
seqeuences that jump and randomly insert into a strand and can cause insertion and deletion mutations
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