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Slide 9, 10, 31, 39, 44/45, 58 |
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An electrical potential recorded from an electrode placed on a muscle |
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And electrical potential from the eyes; detects eye movements |
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Smooth; state of relaxation |
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Irregular; state of arousal |
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Transition b/w wake and sleep -Theta waves |
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10 minutes after stage 1 -Theta waves -If awakened, you might not report that you were sleeping |
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Short bursts of waves -Occur during stages 1-4 -2-5 per minute |
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Sudden, sharp waves -Occur during stage 2 -1 per minute OR after loud noises |
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15 minutes after Stage 2 -Delta waves (20-50% of the time) |
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20 minutes after stage 3 -Delta waves (>50% of the time) -Deepest sleep |
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45 minutes after stage 4/90 minutes after beginning of sleep -Theta and Beta waves -Muscles paralyzed -Report dreams |
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Where in the brain is the biological clock? |
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Not a disease, but may be a symptom of pain, discomfort, or physical ailment -Affects about 25% occasionally, 9% regularly |
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What is one of the most important causes of insomnia? |
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What are the three symptoms of narcolepsy? |
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Definition
An irresistible urge to sleep (sleep attack); cataplexy, sleep paralysis |
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A sudden urge to sleep -sleep for 2-5 minutes and wake up refreshed -usually happens under boring conditions |
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Complete paralysis that occurs during wakefulness -fully conscious -occurs during extreme emotional reactions |
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Hypnagogic hallucinations |
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Definition
Occur during sleep paralysis -dreaming while lying awake |
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What is hypocretin's relationship to narcolepsy? |
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Definition
Destruction of these causes narcolepsy |
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What is hypocretin also known as? |
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REM sleep behavior disorder |
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Definition
Person does not become paralyzed during REM sleep- acts out dreams |
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A fatal inherited disorder -characterized by progressive insomnia |
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Rebound phenomenon (define & example) |
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Definition
The increased frequency/intensity of a phenomenon after it has been temporarily suppressed -after REM deprivation, there is an increase in REM sleep |
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What are the 3 problems associated with slow-wave sleep? |
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Definition
-Bed wetting -Sleepwalking -Night terrors |
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What are the effects of slow-wave sleep deprivation? |
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Definition
Cognitive abilities are affected -trouble concentrating -perceptual distortions -hallucinations |
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What effect does exercise have on slow-wave sleep, and what does this imply? |
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No relationship b/w exercise and the amount of slow-wave sleep -implies that the primary function of slow-wave sleep is not to provide the body with rest |
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What effect does mental activity have on sleep, and what does this imply? |
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Definition
If a part of the brain is stimulated during wakefulness, that part will show more delta waves during slow-wave sleep -implies that slow-wave sleep provides the brain with rest |
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Definition
Occur during slow-wave sleep -the presence of delta waves in a part of the brain indicate that it is resting |
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What percentage of sleep in newborns vs. adults is REM sleep, and what does this imply? |
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Definition
Newborns ~70% Adults ~15% -Implies that REM sleep is important for learning |
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What are the 2 hypotheses for the function of REM sleep? |
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Definition
-Integrates the day's memories with existing memories -Flushes useless memories |
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One of the most important NT involved in arousal -produce activation and cortical desynchrony when stimulated -highest activity during wakefulness and REM sleep |
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Where in the brain are the two groups of ACh neurons located? |
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Definition
-Basal forebrain -Pons (LDT, PPT) |
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Catecholamine agonists that produce arousal and sleeplessness -these effects are caused by the locus coeruleus |
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A group of noradrenergic cell bodies in the pons -involved in arousal and vigilance |
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Play a role in activating behavior -mostly found in the raphe nuclei |
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An amino acid that is involved in the control of wakefulness/arousal -active during wakefulness -low during slow-wave/REM sleep |
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Contains histamine neurons involved in cortical activation and behavioral arousal |
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A peptide -Produced by neurons whose cell bodies are in the hypothalamus -excitatory, wakefulness-promoting effect -active during wakefulness, inhibited during sleep |
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Ventrolateral Preoptic Area (VLPA) |
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Definition
A group of GABA neurons that suppress alertness/behavioral arousal and promote slow-wave sleep |
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PGO wave (pontine, geniculate, occipital) |
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Definition
Bursts of electrical activity starting in the pons, and going to the LGN and visual cortex -in REM sleep |
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Definition
Contains ACh neurons that are involved in the initiation of REM sleep -located in the dorsolateral pons |
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What three parts of the brain are involved in the initiation of REM sleep? |
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Definition
-Peribrachial area -MPRF -Magnocellular nucleus |
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Contains neurons involved in the initation of REM sleep -activated by ACh neurons of the peribrachial area |
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Involved in the paralysis in REM sleep -in the medulla |
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Suprechiasmatic nucleus (SCN) |
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Definition
Contains biological clock that organizes many of the body's circadian rhythms -located in the hypothalamus on top of the optic chiasm |
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Definition
A photopigment in the ganglion cells in the retina that projects info to the SCN |
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Effects of lesions to the SCN (2) |
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-Eliminates circadian rhythm -Sleep pattern disrupted, but not amount of sleep |
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A stimulus (usually light) that resets the biological clock |
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Effect of lesions to retina or optic nerve (remove zeitgebers) |
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-Circadian behaviors are "free-running", not entrained |
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Produces melatonin and plays a role in circadian/seasonal rhythms -attached to the dorsal tectum |
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Plays a role in circadian/seasonal rhythms -secreted at night by the pineal gland |
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