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Chapter 7
Chapter 7
39
Microbiology
Undergraduate 2
03/09/2011

Additional Microbiology Flashcards

 


 

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Term
Genetics
Definition
Study of inheritance and inheritable traints as expressed in an organism's genetic material
Term
Genome
Definition

The entire genetic complement of an organism 

Includes its genes and nucleotide sequences

Term
Plasmids
Definition

Small molecules of DNA that replicate independently

 

NOT ESSENTIAL for normal metabolism, growth, or reproduction

Term
Fertility factors
Definition
Dea with conjugation pili
Term
Resistance factors
Definition
Carries genes for resistance against anti-microbials
Term
Bacteriocin factors
Definition
Carries genes for bacteriocins, which kill bacteria cells of similar species withouth the plasmid (competitors)
Term
Virulence plasmids
Definition
Carry info to make bacteria virulent
Term
Nucleosome
Definition
DNA wrapped around histones
Term
Chromatin Fiber
Definition
Nucleosomes clumped with proteins
Term
Euchromatin
Definition
Active, looseley packed chromatin fibers
Term
Heterochromatin
Definition
Tightly packed inactive chromatin fibers
Term
Leading Strand
Definition
Synthesized continuously
Term
Lagging Strand
Definition
Synthesized discontinously
Term
Topoisomerase
Definition
Removes superoils in DNA molecule
Term
Genotype
Definition
Set of genes in the genome
Term
Phenotype
Definition
Physical features and functional traits of the organism
Term
Central Dogma of Genetics
Definition
DNA is transcriped to RNA, RNA is translated to form polypeptides
Term
rRNA primers
Definition
For DNA polymerase to use during DNA replication
Term
mRNA
Definition
Carries genetic information from chromosomes to ribosomes
Term
rRNA
Definition
combines with ribosomal polypeptides to form ribosomes
Term
tRNA
Definition
delivers correct sequence of amino acids to ribosomes based on nucleotide sequence  in mRNA
Term
Capping
Definition
In eukaryotes, a modified guanine nucleotide is added to the 5' end of mRNA
Term
Polyadenyation
Definition
(Eukaryotes) 100-250 adenine nucleotides are added to the 3' end
Term
Splicing
Definition
Removal of introns to make functional mRNA containing only coding regions called exons
Term
AUG
Definition
Start codon, methionine
Term

UAA

UAG

UGA

Definition
Stop codons
Term
A site
Definition
accomodates a tRNA delivering an amino acid
Term
P site
Definition
holds a tRNA and the growing polypeptide
Term
E site
Definition
discharged tRNAs exit from this site
Term
Mutation
Definition

Change in nucleotide base sequene of a genome

-Rare

-Usually permanent

-Rarely imrpoves 

Term
Point Mutation
Definition

-Most common

-One base pair is affected

-insertions, deletions, substituions

Term
frameshift mutations
Definition
insertions and deletions
Term
Radiation
Definition
Mutagen, Ionizing and Non Ionizing
Term
nucleotide analogs
Definition
Chemical mutagen which disrupts DNA and RNA replication
Term
Nucleotide altering chemicals
Definition
Results in base pair substituions and missense mutations
Term
frameshift mutations
Definition
Result in nonsense mutations
Term
Mutants
Definition
Descendants of a cell that does not repair a mutation
Term
Wild types
Definition
Cells that are normally found in nature
Term
gyrase
Definition
Enzyme which foilds and coils prokaryotic DNA
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