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adrenaline (epinephrine, norepinephrine) |
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How are transmitters released |
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Voltage gated calcium channels in axon terminal are open and calcium triggers exocytosis of neurotransmitters vesicles from their respective neurons |
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How might the activity of a neurotransmitter be terminated |
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GABA firing acts as inhibitory by opening potassium or chloride and calcium channels are closed. Both presynaptic and postsynaptic inhibition. |
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stimulus capable of depolarizing membrane but not by enough to reach threshold |
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stimulus that has more than enough depolarization to reach threshold |
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Have sites for receptors to attach to which can limit the neurotransmitter being released |
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anatomically specialized junction between 2 neurons where electrical activity in one neuron influences excitability of second. |
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cellular structure that holds and releases neurotransmitter at the synapse |
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narrow extracellular space separating pre and post synaptic neurons at chemical synapses |
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excitatory postsynaptic potential: depolarizing graded potential in postsynaptic neuron in response to activation of excitatory synapse |
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inhibitory postsynaptic potential: hyperpolarizing graded potential that arises in postsynaptic neuron in response to activation of inhibitory synaptic endings upon it |
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Neurotransmitter- low. Neuromodulator-varies but tends to be high |
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neurotrasmitter is msec to sec. neuromodulator is minutes to hrs |
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Neurotransmitter is from firing of neuron. Neuromodulator is from neurons and other cells (paracrine) |
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Neurotransmitter is EPSP, IPSP, or intraceullular biochemical reaction. Neuromodulator influences response of neurotransmitter via channels, qty/activity of 2nd messenger, amount of neurotransmitter. |
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one presynaptic neuron fires very rapidly, builds up |
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several neurons fire at same time |
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Temporal and spatial summation |
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Necessary in order to produce a great enough stimulus to reach action potential |
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aromatic rings with alcohol and amine group. |
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aromatic rings with alcohol and amine group. Methyl group attached to the nitrogen. |
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