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due to structure or location |
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"ExHale" ^G<0 or neg free energy, gives off energy, spontaneous |
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"ENhale" ^G>0 or positive free energy, requires addt free energy, not spontaneous |
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First Law of Thermodynamics |
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law of conservation of energy, energy can not be created or destroyed, can be transfered from one type to another |
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Second law of thermodynamics |
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transfer or transformation of energy from on form to another increase entropy or degree of disorder of a system |
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What do the 2 laws of Thermodynamics have to do with biology? |
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Energy is required by all living organisms |
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determines direction of a reaction (if it will be spontaneous or not) |
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an agent that speeds up the rate of a chemical reaction without being consumed during the reaction |
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a protein catalyst in living cells |
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initial input of energy to start a reaction |
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interaction also involves conformational changes |
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location where the reaction takes place |
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reactants that bind to active site |
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INORGANIC....ion that temp binds to the enzyme |
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ORGANIC molecule that participates in reaction but left unchanged afterwards |
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(many drugs) molecule binds to active site, inhibits ability of substrate to bind... |
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noncompetitive inhibition |
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(many cellular activities) inhibitor binds to allosteric site- not active site...changing the enzymes shape and reducing its activity |
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a series of chemical reactions occurring in the cell |
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result in breakdown and are exergonic like digesting food |
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promote synthesis and are endergonic like building new muscle protein, must be coupled to exergonic reaction |
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is the set of chemical reactions that happen in the cells of living organisms to sustain life. |
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