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Chapter 6
The Integumentary System
18
Anatomy
Undergraduate 2
09/07/2008

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Term
Derivatives of the Integumentary System
Definition
1. Nails
2. Hair
3. Sweat glands
4. Sebaceous glands
Term
Skin Functions
Definition
1. Barrier
2. Immunologic function
3. Homeostasis
4. Sensory information
5. Endocrine function
6. Excretion
Term
Two Layers of the Skin
Definition
1. Epidermis
2. Dermis
Term
Layers of the Epidermis
Definition
1. Stratum Basale
2. Stratum Spinosum
3. Stratum Granulosum
4. Stratum Lucidum
5. Stratum Corneum
Term
Cells of the Epidermis
Definition
1. Keratinocytes
2. Melanocytes
3. Langerhan's cells
4. Merkel cells
Term
Basal Cell Carcinoma
Definition
Least malignant; most common.
-Stratum basale
-Surgical excision
Term
Squamous Cell Carcinoma
Definition
Grows rapidly; metastasizes.
-Stratum spinosum
-Surgical excision, radiation therapy
Term
Melanoma
Definition
Cancer of the melanocytes (5% of skin cancers).
-Highly metastatic, resistant to chemotherapy
-1/3 develop from preexisting moles
Term
A, B, C, D, E
Definition
-Assymmetry
-Border irregularity
-Color (many colors)
-Diameter ( >6mm)
-Elevation
Term
Dermis
Definition
Flexible conncective tissue
-Fibroblasts, macrophages, and mast cells are common
Term
Papillary Layer
Definition
-Superficial
-Areolar loose connective tissue
-Dermal papillae
-Meissner's corpuscles
-Dermal/epidermal ridges
-Forms fingerprints
Term
Reticular Layer
Definition
-80% of the thinkness
-Dense irregular connective tissue
-Matrix: interlacing collagen fibers
-Collagen
-Elastin
-Flexure lines
-Stretch marks
Term
Functions of the Skin
Definition
-Chemical barrier
-Physical barrier
-Biological barrier
-Body temperature regulation
-Cutaneous sensation
-Metabolic function
-Blood reservoir
-Excretion
Term
Burns
Definition
Tissue damage caused by intense heat, electricity, radiation, or certain chemicals
-Immediate threat is catastrophic loss of body fluids containing proteins and electrolytes
Term
1st Degree Burns
Definition
Superficial, redness, swelling, pain, epidermis only
Term
2nd Degree Burns
Definition
Epdiermis and upper dermis, redness, swelling, blistering, very painful
Term
3rd Degree Burns
Definition
Full-thinkness burns, entire thickness of the skin, not painful, skin grafts.
Term
Burn Fatality
Definition
Critical if over 25% is 2nd degree burns, over 10% 3rd degree, or 3rd degree on hands, face, or feet.
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