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A physiological organic compund that is secreated by specialized cells and diffuses into the bloodstream with the purpose of inhibiting or stimulating another target tissue or organ. |
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Secretion voided into a Duct |
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Secretion voided into circulation |
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Factors influencing biological activity of hormones |
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1- Presence of receptors for a hormone on a cell
2- Half-Life (t1/2) of the Hormone in circulation |
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Tissues or cells that posses receptors for a hormone being released into the blood stream |
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Period of time during which a substance is reduced to half of its original concentration. Longer half life generates greater biological response |
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Interaction of nervous system and endocrine system to soordinate and regulate all reproductive functions |
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Functions to transduce stimuli into neural signals by two pathways:
1- Simple neural -> secreation of neurotransmitter into target tissue
2- Neuroendocrine reflex -> secreation of neurohormone into blood to remote target tissue |
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substance realesed at synapses for neuronal propegation of the electrical impulse, produced by neurons |
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substance realesed by neurons directly into the blood |
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Neurons release excititory and Inhibitory neurotransmitters that stimulate or inhibit post- synaptic neuropn to fire and action potential |
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complex and critical ara of the brain, containing regions with groups of neurons with similar function called neuclei
*Surge Center, Tonic Center and Paraventricular nucleus (PVN) |
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1) regulates reproduction by interaction with the the Petuitary Gland
2) Neurons srcreate GnRH, Oxytocin
3) Hypothalmic Nuclei- surrounds third ventricle
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"Master Gland"
Anterior and Posterior lobes have different embryonic origions, orginization and secreate different substinces |
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FSH, LH, Prolactin, Growth Hormone, TSH |
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Storage and release of hormone, neuroendocrine cells origionate in hypothalmus and axons extend through stalk to terminate in posterior lobe
Oxytocin, Vasopressin |
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- A.P. fed with a portal blood sytem
-Neurons in Hypoth. releases GnRH to stimulate FSH/LH throguh portal blood system |
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blood vessels that connect capillary networks
-hormones do not have to circulate through entire body to get to petuitary
- smaller secretions ellicit effects |
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Posterior Petuitary Neurons |
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-Secreate directly into blood flow |
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