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Chapter 45
Perioperative, intraoperative & postoperative complications in gynecologic surgery
14
Medical
Graduate
08/21/2013

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Term
What are the four groups of conditions for which prophylaxis for endocarditis should be considered before surgery?
Definition

1. Prosthetic cardiac valve or repair

2. Previous infective endocarditis

3. Congenital heart defects: recently, incompletley or unrepaired defect

4. Transplant patient who has developed valvulopathy

Term
In pre-operative evaluation, what are the criteria for high risk for VTE?
Definition

VTE in the past 3 months

or

Severe thrombophilia (e.g. protein S, C or antithrombin deficiency, APLA)

 

Term
In pre-operative evaluation, what are the 4 groups of moderate-risk for VTE?
Definition

1. VTE in the past 3-12 months

2. Nonsevere thrombophilic conditions

3. Recurrent VTE

4. Active cancer (treated in the past 6 months or palliative)

Term
In preoperative evaluation, which patients are considered to be at low risk for VTE?
Definition
Single VTE >12 months ago
Term
How should various anticoagulants be handeled before and after surgery?
Definition

Warfarin - stopped 5 days pre-op

Antiplatelets (aspirin, clopidogrel) - stopped 7-10 days pre-op

NSAIDs: short half-life (indomethacin, ibuprofen) - day of surgery; intermediate (naproxen, celecoxib) - 2-3 days pre-op; long half-life (>20hrs) - 10 days pre-op

 

INR≥1.5 1-2 days pre-op - give 1-2mg vitamin K PO

 

Vitamin K antagonists and antiplatelet drugs resumed 24-48hrs post-op

Term
When performing bridging with low-dose LMWH or heparin for a patient at risk for VTE, when should the last dose of therapeutic LMWH be given pre-op, and when should it be resumed?
Definition

Last therapeutic dose is given on the morning the day before surgery.

Treatement resumed 24hrs after a minor procedure, 48-72hrs after a major procedure.

Term

What is the relative risk of post-op pulmonary complications in the following situations?

a. COPD

b. Age

c. ASA class ≥II

d. Functional dependence

e. CHF

f. Smoking

g. Obesity

h. Mild or moderate asthma

Definition

a. COPD - RR=1.8

b. Age - 60-69 - RR=2; ≥70 - RR=3

c. ASA class ≥ II - RR=4.9

d. Completely functionally dependent - RR=2.5; pariatlly dependent - RR=1.7

e. CHF - RR=3

f. Smoking - RR=1.26

g. Obesity - not significant

h. Mild or moderate asthma - not significant

Term
How does femoral nerve injury present?
Definition
Weakness or inability to flex the hip and extend the knee, parasthesia over the anterior and medial thigh and medial aspect of the calf.
Term
How does obturator nerve injury present?
Definition
Sensory loss in the upper medial thigh and motor weakness in the hip adductors
Term
Which two nerves are at risk for injury in a Pfannenstiel (low transverse abdominal) incision is performed?
Definition

Ilioinguinal

Iliohypogastric

Term
Under what conditions should VTE prophylaxis be administered?
Definition

Brief or laparoscopic procedure in a patient with risk factors

 

Major gynecologic procedure

 

Start just prior to surgery and continue until discharge. In patients with active malignancy, continue for 2-4 weeks.

Term
What are the options for VTE prophylaxis?
Definition

 Low-dose heparin twice daily

 

LMWH once daily

 

Intermittnet pneumatic compression (IPC) for the exteremeties

Term
What is the classification of hysterectomies for risk of infectious complications? What, if any, antibiotics should be perscribed pre-op?
Definition

Clean-contaminated

 

Give cefazolin 1gr pre-op

Term
How does necrotizing fasciitis present?
Definition

Clinical triad: sepsis, inordinate pain, unilateral edema

 

Affected skin is usually cool, gray, boggy and may reveal crepitus

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