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Chapter 43
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32
Biology
Undergraduate 1
02/15/2014

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Term
Immune System
Definition
The body's responses to infection that take many forms, including proteins on cell membranes, and immune cells in tissues and body fluids.
Term
Innate Immunity
Definition
Our systems that protect us indiscriminately, like our skin, and the secretions in our various openings that are purposed to kill potentially infectious intakes.
Term
Proteins of innate immunity
Definition
Proteins that do not bond to cells we are supposed to have, can trigger response to wide (Broad variety of common pathogens are targeted) of intruders.
Term
Adaptive immunity
Definition
Unlike the proteins of innate immunity,vertebrates can produce proteins that bond to specific threats, this is why vaccinations work.
Term
Histamine
Definition
Important inflammatory signalling molecule stored in the granules of Mast Cells pg 980
Term
Mast Cells
Definition
Release Histamines when inflammatory response is needed in an area. Found in connective tissues. pg 980
Term
cytokines
Definition
Signalling Molecules released by macrphoages to enhance immune response at an area. pg 980
Term
epitope
Definition
The small and accessible portion of an antigen that bonds to the antigen receptor is an epitope. pg 981
Term
heavy and light chains
Definition
All B cell antigen receptors are roughly 'Y' shaped, and have heavy and light chains (2 of each) linked together by disulfide bridges. pg 981
Term
lymphocytes
Definition
White blood cells that are T and B cells. Important in adaptive immunity. pg 981
Term
thymus
Definition
An organ in the thoracic cavity, above the heart. In this organ, developing white blood cells migrate from the bone marrow and mature into T cells. pg 981
Term
antigen
Definition
any substance that elicits a response from a B or T cell is called an antigen pg 981
Term
antigen receptor
Definition
antigen receptors are proteins. When the antigen receptor of a T or B cell binds to an antigen at the antigen receptor, a response is triggered. pg 981
Term
antibody
Definition
A secreted protein, also sometimes called immunoglobulin (Ig). Have y shaped structure, like B cell anigen receptors, but are secreted by B cells instead of being attached to them. many functions in pathogen identification and hindrance. pg 982
Term
MHC (major histocompatibility complex) molecule
Definition
The host protein that displays antigens to T cells. pg 983
Term
Self Tolerance
Definition
Important immune concept, our immune system SHOULD not attack our own body. Sometimes this is not the case.
Term
effector cells
Definition
product of T cell clonal reproduction, short lived cells that take effect immediately against the antigen detected, and and pathogens that produce aforementioned antigen. pg 985
Term
memory cells
Definition
Longer lived cells from the T cell clonal selection, keep adaptive immune response ready to be triggered for decades.
Term
clonal selection
Definition
the proliferation (by making two types of offspring)of a lymphocyte into clone of cells in response to binding to an antigen. pg 985
Term
primary immune response
Definition
Before our adaptive immunity knows of a cell, this is our response to the first exposure of a pathogen. OFten takes longer to fight pathogen than secondary responses. pg 985
Term
secondary immuns response
Definition
The hallmark of adaptive response. Our stored immune cells for pathogen give rise to a swift response to familiar pathogens in body. pg 985
Term
humoral immune response
Definition
immune response in blood and lymph.
Term
cell mediated immune response
Definition
specialized T cells destroying infected host cells.
Term
Helper T Cells
Definition
trigger to both humoral and cell mediated immune response. Signal cells to begin production of antibodies and activate T cells that will kill cells
Term
antigen presenting cell
Definition
A cell bearing an antigen on its surface. pg 986
Term
cytotoxic T cells
Definition
T cell that kill infected (usually) cells in the body. pg 987
Term
plasma cells
Definition
the antibody secreting offspring of B cells. pg 988
Term
active immunity
Definition
defences that arise when a pathogen infects the body and prompts primary or secondary immune response. pg 990
Term
passive immunity
Definition
When a mother transfers antibodies to an unborn child, the immunity in this child is passive, as it has never directly responded to the pathogen.
Term
immunization
Definition
when immunity develops from the introduction of antigens into the body. see early vaccine methods. pg 991
Term
vaccination
Definition
Same as immunization, exposure to a dead or inert version of pathogen, body learnd to recognize antigens, pg 991
Term
monoclonal antibodies
Definition
antibodies produced from the clones of one B cell
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