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Nerve cells scattered in body No central organ ex: Cnidarians |
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Nerve ring and nerves extend to various parts of the body
Ex: Echinoderms |
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nerve cells concentrate, form: -nerves, nerve cords, ganglia, brain
Sense Organs: -typically concentrated in head
Increased # of interneurons, more complex synaptic contacts: -permit wide range of responses |
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Cerebral ganglia Ventral nerve cords Transverse nerves |
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Ventral nerve cord Numerous ganglia -cerebral ganglia(arthropods) |
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Two main divisions of vertebrate nervous system |
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Central nervous system: -brain, spinal cord
Peripheral nervous system: -sensory receptors and nerves |
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Brain and spinal cord arise from the neural tube
Anterior end of neural tube differentiates into: -hindbrain -midbrain -forebrain |
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Protected by bone and 3 meninges -dura mater -arachnoid -pia mater
Cushioned by cerebrospinal fluid (CSF) |
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What are spaces in the brain called? |
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Definition
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Structure and function of Spinal Cord |
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Transmits impulses to and from brain: -ascending tracts (info to brain) -descending tracts(info from brain) Controls many reflex actions Gray matter -contains nuclei that serve as reflex centers |
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Structures of the Cerebrum |
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Definition
White matter -lies beneath cerebral cortex Corpus callosum -large band of white matter -connects R & L hemispheres Basal ganglia -cluster of nuclei w/in white matter -important centers for motor funct |
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What are the functional areas of the cerebrum? |
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Occipital lobe-sight
etc... |
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Limbic System of the brain |
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Definition
Affects emotional aspects of behavior -motivation -sexual activity -autonomic responses -biological responses |
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Parts of the limbic system |
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Hippocampus: -helps categorize info -consolidates memories
Amygdala: -evaluates incoming info -signals danger |
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Learning -process of acquiring knowledge or skills as a result of experience
Memory -process by which info is encoded, stored, and retrieved |
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What are the types of memory? |
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Implicit memory
Explicit memory
Short-term
Long-term |
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-unconscious how-to memory -for perceptual and motor skills |
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factual memory of people, places, objects |
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recalls info(like phone #) for a few minutes
info can be transferred from short to long memory |
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long-term functional changes at synapses |
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increased sensitivity to an action potential by a postsynaptic neuron |
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long-lasting decrease in strength of synaptic connections |
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permits the body to respond to stressful situations |
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influences organs to conserve and restore energy
ex: digestive, metabolism |
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Peripheral nervous system |
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Definition
made up of : -sensory receptors -neurons outside the CNS |
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What are the steps of Response to a Stimulus? |
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Definition
1. Reception 2. Transmission by afferent 3. Integration 4. Transmission by efferent 5. Action by effectors |
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What is the structure of a typical neuron? |
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Definition
Dendrites Axon Nodes of Ranvier Schwann cell Myelin Sheath Synaptic terminals Cell body |
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Where 2 myelin sheaths come together
axon is not covered by the myelin here
Na+ channels are concentrated |
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coats the axon to speed up signal transmission
Forms sheaths around axons in PNS |
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several hundred axons wrapped in connective tissue |
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Mass of neuron cell bodies in the PNS |
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Definition
support/nourish cells
A type of schwann cell
important in neural communication |
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Definition
A type of glial cell: -physically support neurons -regulate extracellular fluid in CNS -communicate with one another & with neurons -induce and stabilize synapses |
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form myelin sheaths around axons in CNS |
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Definition
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Line cavities in the CNS
Contribute to formation of cerebrospinal fluid
serve as neural stem cells |
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How do neurons send signals? |
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Definition
-Electrical signals transmit info along axons -Plasma membrane of resting neuron(not transmitting) is polarized -Inner surface of plasma membrane is negatively charged relative to the extracellular fluid |
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What is the approximate resting potential of a neuron? |
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Definition
Potential difference of about : -70 mV across the membrane |
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What determines the magnitude of resting potential? |
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Definition
-Differences in ion concentrations inside cell relative to extracellular fluid
-selective permeability of plasma membrane to these ions |
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What gives the cells charges? |
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Definition
-Ions passing through specific passive ion channels. -K+ leak out faster than Na+ leak in -Cl- accumulates at inner surface of plasma membrane -Large ions can't cross membrane, so contribute to negative charge. |
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Describe the Sodium-Potassium pump |
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Definition
It maintains gradients that determine resting potential by transporting 3 Na+ out for ever 2 K+ in.
It requires ATP |
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Resting potential of a neuron is maintained by.. |
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Definition
Differences in concentrations of specific ions inside the cell relative to extracellular fluid
Selective permeability of the plasma membrane to these ions |
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Definition
-A local change in electrical potential -Varies in magnitude depending on the strength of the applied stimulus -Fades out within a few mm of point of origin |
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-An electrical signal resulting from depolarization of the plasma membrane in a neuron or muscle cell -wave of depolarization that moves down the axon |
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depolarized: -if stimulus causes membrane potential to become less negative hyperpolarized: -if membrane potential becomes more negative than resting potential |
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How is an action potential generated? |
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Definition
-When voltage across membrane declines to a threshold level -voltage-activated ion channels open -Na+ ions flow into the neuron |
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Describe transmission of an Action Potential |
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Definition
An all or none response: -No variation in strength of a single impulse
-either exceeds or doesn't Once begun, it must finish
As moves down an axon, repolarization occurs behind it |
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The brief period that elapses after the response of a neuron or muscle fiber, during which it cannot respond to another stimulus. |
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What are the 2 types of refractory periods? |
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Definition
Absolute: -can not transmit another action potential
Relative: When enough gates controlling Na+ have ben reset, the threshold is higher for an action potential to reach |
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Definition
-The transmission of a neural impulse along a myelinated neuron -ion activity at one node depolarizes the next node along the axon -more rapid than continuous |
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-Involves entire axon plasma membrane -takes place in unmyelinated neurons -must pass entire length of axon, so is slower than saltatory |
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Junction between 2 neurons or between a neuron and an effector
Most are chemical, some are electrical |
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What do synaptic vesicles contain? |
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Definition
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How do neurons signal other cells? |
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Definition
By releasing neurotransmitters at synapses |
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What ion makes a synapse work? |
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Definition
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How is a neural impulse transmitted across a synapse? |
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Definition
-Calcium ions cause synaptic vesicle to fuse with presynaptic membrane and release neurotransmitter into synaptic cleft -Neurotransmitter diffuses across synaptic cleft and combines with specific receptors on a post synaptic neuron |
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Definition
a presynaptic neuron releases neurotransmitter(chemical messenger) from its synaptic vesicles. |
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Excitatory postsynaptic potential (EPSP) |
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Definition
A change in membrane potential that brings a neuron closer to the firing level |
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Inhibitory postsynaptic potential (IPSP) |
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Definition
A change in membrane potential that takes a neuron farther from the firing level. |
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Occurs when repeated stimuli cause new EPSPs to develop before previous EPSPs have decayed |
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Occurs when several closely spaced synaptic terminals release neurotransmitter: simultaneously stimulating postsynaptic neuron at several different places |
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What happens during integration? |
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Definition
-Incoming neural signals are summed -temporal and spatial summation can bring a neuron to threshold level |
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Definition
several presynaptic neurons synapse with one postsynaptic neuron |
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A single presynaptic neuron synapses with many postsynaptic neurons. |
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Definition
Important in rhythmic breathing, mental alertness, short-term memory
Depend on positive feedback: -new impulses generated again and again until synapses fatigue |
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Term
What are the 2 types of reverberating circuits? |
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Definition
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Reverberating circuit with interneuron |
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Definition
-An axon collateral of the second neuron synapses with an interneuron. -Interneuron synapses with the first neuron in the sequence New impulses are triggered again and again in the first neuron, causing reverberation |
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Simple reverberating circuit |
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Definition
An axon collateral of the 2nd neuron turns back on its own dendrites, so the neuron continues to stimulate itself |
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