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Chapter 3
Neural Conduction and Synaptic Transmission
27
Psychology
Undergraduate 3
09/01/2015

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Term
Where are action potentials generated?
Definition
in the axon initial segment
Term
Decremental
Definition
decreasing in amplitude while traveling through the neuron
Term
Threshold of excitation
Definition
when the sum of the depolarizations and hyperpolarizations reaching the axon initial segment at any time is sufficient to depolarize the membrane, thus creating an action potential
Term
How long does an action potential (AP) last?
Definition
approximately one millisecond
Term
What is the all-or-none principle?
Definition
action potentials either happen or they don't. there are no weak action potentials and there are no strong action potentials. either they are, or they're not
Term
Integration
Definition
adding or combining a number of individual signals into one overall signal
Term
Saltatory conduction
Definition
the transmission of action potentials in myelinated axons
Term
What is the maximum velocity of conduction in human motor neurons?
Definition
60 meters per second
Term
Directed synapses
Definition
synapses at which the site of neurotransmitter release and the site of neurotransmitter reception are in close proximity
Term
Nondirected synapses
Definition
synapses at which the site of release is at some distance from the site of reception
Term
Coexistence
Definition
when a neuron contains more than one neurotransmitter
Term
Exocytosis
Definition
the process of releasing a neurotransmitter
Term
Acetylcholine
Definition
a neurotransmitter that is created by the addition of an acetyl group to a choline molecule
Term
Acetylcholinesterase
Definition
the enzyme that breaks down the neurotransmitter acetylcholine
Term
Agonists
Definition
drugs that facilitate the effects of a particular neurotransmitter
Term
Amino acid neurotransmitters
Definition
a class of small-molecule neurotransmitters, which includes the amino acids: glutamate and GABA
Term
Anandamide
Definition
the first endogenous endocannabinoid to be discovered and characterized
Term
Antagonists
Definition
drugs that inhibit the effects of a particular neurotransmitter
Term
Antidromic conduction
Definition
axonal conduction opposite to the normal direction; conduction from axon terminals back toward the cell body
Term
Aspartate
Definition
an amino acid neurotransmitter that is a constituent of many of the proteins that we eat
Term
Atropine
Definition
a receptor blocker that exerts an antagonistic effect at muscarinic receptors
Term
Autoreceptors
Definition
a type of metabotropic receptor located on the presynaptic membrane and sensitive to a neurons own neurotransmitter
Term
Axon initial segment
Definition
the segment of the axon where action potentials are generated-located immediately adjacent to the axon hillock
Term
Dendritic spines
Definition
tiny nodules of various shapes that are located on the surfaces of many dendrites and are the sites of most excitatory synapses in the mature mammalian brain
Term
Metabotropic receptors
Definition
receptors that are associated with signal proteins and G proteins
Term
Miscellaneous peptides
Definition
one of the five classes of neuropeptide transmitters; it consists of those that don't fit into the other four classes
Term
Monoamine neurotransmitters
Definition
small-molecule neurotransmitters that are synthesized from monoamines and comprise two classes: catecholamines and indolamines
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