Shared Flashcard Set

Details

Chapter 3
Proteins 1: Composition and Structure
27
Biochemistry
Undergraduate 2
08/25/2011

Additional Biochemistry Flashcards

 


 

Cards

Term
general structural features of amino acid
Definition

1.amino group

2.carboxyl group

3.hydrogen

4.side chain/residue

Term
side chains
Definition
define the nature and structure of different amino acids
Term
peptides
Definition
polymers of amino acids
Term
condensation
Definition

formation of peptide (amide) bond

thermodynamically unfavorable

Term
dipeptide
Definition
2 residues
Term
tripepetide
Definition
3 residues
Term
oligopeptide
Definition
several residues
Term
polypeptide
Definition
many residues
Term
direction for numbering the residues
Definition
N- to C-terminus
Term
ionization state
Definition
N-terminus, C-terminus, dissociable groups in the side chains
Term
hydrolysis
Definition

peptide yields the constituent amino acids

thermodynamically favorable

Term
chiral center
Definition
four items linked to central carbon that are all different
Term
amino acids of human proteins
Definition
L-isomers
Term
amino acids of bacteria
Definition
D-isomers
Term
unionized
Definition
H2N-CH(-R)-COOH
Term
cationic
Definition

H3N-CH(-R)-COOH

low pH

Term
Anionic
Definition

H2N-CH(-R)COO-

high pH

Term
Dipolar (Zwitterionic)
Definition

H3N-CH(-R)-COO-

neutral pH

Term
classification of amino acids
Definition
polarity, acid-base propertie, sides or R groups
Term
pK range of alpha carboxyl
Definition
1.7-2.6
Term
pK range of alpha amino
Definition
8.8-10.8
Term
acidic amino acids
Definition
have negatively charged R groups at physiologic pH of 7.0
Term
pKa range from aspartate and glutamate side chains
Definition
3.0-5.5
Term
basic amino acids
Definition
generally have positrly charged R groups at physiologic pH of 7.0
Term
pKa of Lysine
Definition
10.53
Term
pKa of Arginine
Definition
12.48
Term
pKa of Histidine
Definition
6.0
Supporting users have an ad free experience!