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Chapter 2 Terms
Chemical Principles
20
Biology
Undergraduate 1
02/09/2014

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Term
Macromolecules
Definition
Large and complex molecules that make up chemical building blocks of organisms. (Carbs, Lipids, Proteins, Nucleic acids, ATP)
Term
Organic Molecules
Definition
Contain Carbon; C skeleton is represented by R; functional groups: OH Hydroxyl, NH2 Amino, COOH Carboxyl
Term
Carbohydrates
Definition
Sugars and starches; very abundant in cells; made up of C, H, and O; ratio of H : O is 2:1

Simple sugars; monosaccharides, ribose, glucose, fructose

Complex carbs: polysaccharides
Term
Functions of Carbs
Definition
Sugars of DNA and RNA

Cell wall of bacteria

Food reserves

Main function is to supply cell with energy
Term
Monosaccharides
Definition
Simple sugars
Number of carbons 3-7
Triose (3C), Tetrose (4C), Pentose(5C), Hexose(6C), Heptose(7C)

Pentoses are found in DNA and RNA, hexosses are like glucose, fructose
Term
Disaccharides
Definition
Dimers, 2 monosaccahrides joined together by dehydration synthesis rx

Glycosidic bond between two adjacent monosaccharides

Glucose + fructose = sucrose
Glucose + Galactose = Lactose

Isomers: have same chemical but different structural formula
Term
Polysaccharides
Definition
Complex macromolecules, 8 or more monosacchardies joined together

Glycogen: many glucose monomers joined, main energy molecule in animals, and some bacteria

Cellulose: many glucose joined but different linkage, make cell wall of plants
Term
Lipids
Definition
Essential for structure and function of membranes

Non polar molues, insoluble in water

Contain C,H,O but not the 2:1 ratio (H:O)

Also functions in energy storage
Term
Simple Lipids
Definition
Fats or triglycerides

Contain an alcohol glycerol (3C) and fatty acids

Fatty acids are long chain hydrocarbons (C,H). Even number of C and COOH.

Linkage b/n glycerol and F.A. is called an ester bond.
Term
Saturated vs Unsaturated
Definition
Saturated have the max # of H atoms attached to carbon (animal fat)

Unsaturated do not have max # of H attached therefore has double bonds (vegetable oils)
Term
Complex Lipids
Definition
Contain S, P, or N in addition to the main elements.

Phospholipids are most common and important. Main lipids found in cell membranes.
Term
Phospholipids
Definition
Hydrophobic region which is the fatty acid tail

Hydrophilic region which is the glycerol and Phosphate

make up the lipid bilayer of the cytoplasmic membranes
Term
Steroids
Definition
Complex lipids with fused rings

Found mainly in plasma membrane of eukaryotic cells

Mycoplasma are the only genus of bacteria that have sterols in their plasma membrane
Term
Proteins
Definition
Make up 50% of the cell's weight

Contain C, H, N, O and sometimes P and S

Essential for structure and function of cell
Term
Amino Acids
Definition
building block of protein

join together by a peptide bond

Amino acides have a central alpha C, that has a carboxyl (COOH), amino (NH2) and an R group attached to it

20 different amino acids in nature
Term
Amino Acid Formation
Definition
Sterioisomers, the DL and L forms

Most AA are found in the L forms

Bonds between carboxy terminus of one AA to the amino terminus of another are called peptide bonds

Dipeptide - tripeptide - polypetide
Term
Protein Structure
Definition
Primary: linear arrangement of the amino acids. Genetically determined.

Secondary: localized, repeated folding of each polypeptide. H bonds b/n peptide bonds.

Tertiary : three dimensional structure of polypeptide. Interactions b/n side chains of A.A.

Quaternary: exits in proteins with 2 or more polypetides. Overall interaction b/n different polypeptides.
Term
DNA
Definition
Is a double stranded, superhelical molecule. ( Watson and Crick ).

Strands are complimentary and anti parallel.

Contains A, T, G, C

A pairs with T, and C pairs with G.
Term
RNA
Definition
Single stranded molecule

Has ribose as sugar

Contains A,U,G,C

Adenine pairs with uracil, and guanine pairs with cytosine

Three kinds of m-RNA, r-RNA, and t-RNA
Term
Adenosine Triphosphate
Definition
ATP

Primary energy source of the cell

Energy is the high phosphate bonds

Adenosine: adenine + ribose + 3 phosphates

ATP = ADP + Pi

Has ribose, adenine, and 3 phosphate groups.
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