Term
Is the ANS part of the CNS or the PNS? |
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Definition
PNS
peripheral nervous system |
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Term
What is the PNS made up of? |
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Definition
ANS, Sensory Nerves, Somatic Nerves |
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Term
What is the ANS made up of? |
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Definition
Parasympathetic Nervous System
Sympathetic Nervous System |
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Term
What receptors are found in the parasympathetic nervous system? |
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Definition
Muscarinic receptors
Nicotinic receptors |
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Term
What receptors are found in the sympathetic nervous system? |
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Definition
Alpha receptors: a1, a2
Beta receptors: B1, B2 |
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Term
Where are the main nerve centers for the ANS located? |
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Definition
hypothalamus
medulla
spinal cord |
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Term
In the ANS how are nerve impulses carried from the CNS? |
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Definition
Nerve impulses are carried from the central nervous system to the outlying organs via a two-neuron system. |
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Term
How does the two-neuron nerve impulse transmission work in the ANS? |
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Definition
Axons from the CNS neurons end in the ganglia (group nerve cell bodies that are packed together)located just outside the CNS. These ganglia receive info. from the preganglionic neuron that started in the CNS and relay that info. along postganglionic neurons. The postganglionic neurons transmit impulses to the neuroeffector cells- muscles, glands & organs. |
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Term
Where are the originating cells of the sympathetic nervous system? |
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Definition
thoracic & lumbar spinal cord |
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Term
Where are the originating cells of the parasympathetic nervous system? |
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Definition
cranium & sacral spinal cord |
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Term
Where is the location of the nerve ganglia in the sympathetic nervous system? |
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Definition
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Term
Where is the location of the nerve ganglia in the parasympathetic nervous system? |
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Definition
Within or near effector organs |
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Term
In the sympathetic nervous system the preganglionic nerve axons are______and the postganglionic nerve axons are______. |
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Definition
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Term
In the parasympathetic nervous system the preganglionic nerve axons are______and the postganglionic nerve axons are______. |
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Definition
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Term
In the sympathetic nervous system the preganglionic neurotransmitter is __________and the postganglionic neurotransmitter is ________. |
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Definition
acetylcholine
norepinephrine, epinephrine |
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Term
In the parasympathetic nervous system the preganglionic neurotransmitter is __________and the postganglionic neurotransmitter is ________. |
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Definition
acetylcholine
acetylcholine |
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Term
In the sympathetic nervous system the neurotransmitter terminator is? |
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Definition
monoamine oxidase, MAO
catechol-O-methyl transferase, COMT |
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Term
In the parasympathetic nervous system the neurotransmitter terminator is? |
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Definition
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Term
What is the action of the adrenal gland when stimulated by the sympathetic nervous system? |
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Definition
The cromaffin cells of the adrenal medullae secrete epi or norepi directly into the bloodstream. (the ganglia/postganglionic axon evolved into the adrenal medullae) |
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Term
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Definition
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Term
What are adrenergic nerves? |
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Definition
Sympathetic postganglionic nerves that synthesize, store and release norepinephrine. Adrenergic nerves also found in the CNS and chromaffin cells of the adrenal medulla. |
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Term
What group of structurally related chemicals does norepinephrine belong to? |
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Definition
Catecholamines
(along w/ dopamine, serotonin & epinephrine) |
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Term
What are the adrenergic receptors sites that react to the chemical norepinephrine? |
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Definition
Alpha-receptors: a1 & a2
Beta-receptors: B1 & B2 |
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Term
Where are alpha 1 receptors found? |
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Definition
blood vessels
iris and urinary bladder |
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Term
What are the effects of stimulated alpha 1 receptors? |
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Definition
BV: vasoconstriction & increase peripheral resistance to raise BP
Iris: dilate pupil
Urinary Bladder: closure internal sphincter |
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Term
Where are alpha 2 receptors found? |
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Definition
On nerve membranes and act as modulators of norepinephrine release to help prevent overstimulation of released norepinephrine. (some of norepi released from post gang. does not bind to a1 receptors and flows back to react w/ a2 on nerve membrane causing a decrease in release to norepi to prevent overstimulation)
Also found on beta cells of pancrease to moderate insulin release stimulated by SNS activation |
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Term
Where are Beta 1 receptors found? |
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Definition
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Term
What are the actions of Beta 1 receptors? |
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Definition
Cardiac: Incr. HR
Peripheral tissue: incr. lipolysis (breakdown fat) for energy in peripheral tissues
BV: vasodilation
Bronchi: vasodilation
Periphery: Incr. muscle & liver breakdown glycogen & incr. glucagon release from pancreas.
Uterus: relax uterine smooth muscle |
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Term
Where are Beta 2 receptors found? |
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Definition
Smooth muscle in bv, bronchi, periphers and uterine |
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Term
What are the actions of stimulated B2 receptors? |
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Definition
BV: vasodilation
Bronchi: vasodilation
Periphery: Incr. muscle & liver breakdown glycogen & incr. glucagon release from pancreas.
Uterus: relax uterine smooth muscle |
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Term
What are the actions of monoamine oxidase MAO and catechol-O-methyl transferase COMT enzymes? |
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Definition
The are found in the area of released norepinephrine and in the liver to metabolize or biotransform any remaining norepinephrine in the synaptice cleft area or absorbed into circulation. This helps in the termination of the response to norepinephrine. |
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