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Chapter 27
Reproductive Systems
162
Anatomy
Undergraduate 2
05/07/2012

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Term
What are the primary sex organs?
Definition
testes in males, ovaries in females
Term
What do gonads produce?
Definition
sex cells called gametes and secrete hormones
Term
What are the accessory reproductive organs?
Definition
ducts, glands, and external gentialia
Term
What do sex hormones play roles in?
Definition
development and function of the reproductive organs, sexual behaviors and drives, growth and development of many other organs and tissues
Term
What are the accessory ducts for females?
Definition
uterine tubes, uterus, and vagina
Term
What are teh female's internal gentialia?
Definition
ovaries and the internal ducts
Term
What are the cells around the oocyte called?
Definition
follicle cells, granulosa cells
Term
WHat is the primordial follicle?
Definition
one layer of squamouslike follicle cells surrounds the oocyte
Term
What is a Primary follicle
Definition
two or more layers of cuboidal granulosa cells enclose the oocyte
Term
What is a secondary follicle?
Definition
fluid filled space between granulosa cells that coalesces to form a central antrum
Term
What is a graffian follicle
Definition
secondary follicle at its most mature stage that bulges from the surface of the ovary
Term
What is ovulation?
Definition
ejection of the oocyte from the ripening follicle
Term
What is the corpus luteum?
Definition
ruptured follicle after ovulation
Term
What is the zona pellucida?
Definition
membrane surrounding the plasma membrane of an oocyte
Term
Where does sperm bind during fertilization?
Definition
zona pellucida
Term
How long does the follicluar phase last?
Definition
1-14 days
Term
What is the follicular phase?
Definition
period of follicle growth
Term
What is the luteal phase?
Definition
period of corpus luteum activity
Term
How long does the luteal phase last?
Definition
from days 14-28
Term
When does ovulation occur?
Definition
midcycle
Term
Follicular Phase: Step 1
Definition
Primordial follicle, directed by the oocyte, becomes a primary follicle
Term
Follicular Phase: Step 2
Definition
Primary follicle becomes a secondary follicle
Term
Follicular Phase: Step 2a
Definition
Theca follicule and granulosa cells cooperate to produce estrogens
Term
Follicular Phase: Step 2b
Definition
Zona pellucida forms around oocyte
Term
Follicular Phase: Step 2c
Definition
Antrum is formed, fluid filled cavity separating the oocyte from teh rest of the follicle
Term
Which parts of teh follicular phase are functional?
Definition
Step 2a. Theca follicule and granulosa cells cooperate to produce estrogens
Term
What parts of the follicular phase are structural changes?
Definition
2b and 2c. Zona pellucida forms around oocyte, antrum is formed
Term
Follicular Phase: Step 3
Definition
SEcondary follicle becomes a vesicular follicle
Term
Follicular Phase: Step 3a
Definition
antrum expands and isolates the oocyte and the corona radiata
Term
Follicular Phase: Step 3b
Definition
Full size follicle (vesicular follicle) bulges from the external surface of the artery
Term
Follicular Phase: Step 3c
Definition
Primary oocyte completes meiosis and teh stage is set for ovulation
Term
When does ovulation occur?
Definition
ovary wall ruptures and expels the secondary oocyte
Term
What is mittelschmerz?
Definition
twinge of pain sometimes felt during ovulation?
Term
What happens if more than one secondary oocyte is released?
Definition
if fertilized, fraternal twins
Term
What happens during the luteal phase?
Definition
ruptured follicle collapses, granulosa cells enlarge, and along internal thecal cells, form the corpus luteum
Term
What does the corpus luteum secrete?
Definition
progestrone and estrogen
Term
What happens if pregnancy does not occur during the luteal phase?
Definition
corpus luteum degenerates in 10 days leaving a scar
Term
What happens if pregnancy does occur during the luteal phase?
Definition
produces hormones until the placenta takes over that role (at about 3 months)
Term
What receieves the ovulated oocyte provides a site for fertilization?
Definition
fallopian tubes
Term
What are teh four regions of the fallopian tubes?
Definition
fimbriae, infundibulum, ampulla, isthmus
Term
Fallopian Tubes: Fimbriae
Definition
contain cilia that beat creating currents to carry the oocyte into the fallopian tube
Term
Fallopian Tubes: Infundibulum
Definition
catches and channels the released eggs
Term
Fallopian Tubes: Ampulla
Definition
long central portion through which oocyte travels
Term
Fallopian Tubes: Isthmus
Definition
site of connection of fallopian tube to uterus where oocyte enters uterus
Term
Do the uterine tubes come in contact with the ovaries?
Definition
no
Term
What happens after the ovulate oocyte is taken up by the fallopian tubes?
Definition
cast into the peritoneal cavity
Term
How is teh oocyte carried toward the uterus?
Definition
peristalsis and ciliary aciton
Term
Parts of the Uterus
Definition
body, fundus, isthmus
Term
What is the body of the uterus?
Definition
major portion of the uterus
Term
What is the fundus?
Definition
rounded region superior the the entrance of the uterine tubes
Term
What is teh isthmus?
Definition
narrowed region between the body and cervix
Term
What is the cervix?
Definition
narrow neck which projects into the vagina inferiorly
Term
What is the cervical canal?
Definition
cavity of the cervix
Term
What does the cervical canal communicate with?
Definition
vagina and the uterine body
Term
How does the cervical canal communicate with the vagina?
Definition
external os
Term
How does the cervical canal communicate with the uterine body?
Definition
via the internal os
Term
What is teh role of the mucus secreted by the cervical glands?
Definition
covers the external os and blocks sperm entry except during midcycle
Term
What are the three walls of the uterus?
Definition
endometrium, myometerium, perimetrium
Term
What is the uterine endometrium?
Definition
mucosal lining of the uterine cavity
Term
What is the uterine myometrium?
Definition
middle layer; interlacing layers of smooth muscles
Term
What is uterine perimetrium?
Definition
outermost serous layer, the visceral peritoneum
Term
What are the three coats of teh vaginal wall?
Definition
fibroelastic adventitia, smooth muscle muscularis, stratified squamous mucosa
Term
What are teh structures of the vulva?
Definition
greater vestibular glands, clitoris, mons pubis, labia majora, labia minora
Term
What are teh structures of the vulva?
Definition
greater vestibular glands, clitoris, mons pubis, labia majora, labia minora
Term
What are teh greater vestibular glands?
Definition
pea-size glands flanking the vigaina, homologous to the bulbourethral glands
Term
Role of the greater vestibular glands?
Definition
keep the vestibule moist and lubricated
Term
What is the mons pubis?
Definition
round, fatty area overlying the pubic symphysis
Term
What are the mammary glands?
Definition
modified sweat glands consisting of 15-25 lobes that radiate around and open at the nipple
Term
What is contained within the lobes to produce milk in lactating women?
Definition
glandular alveoli
Term
How is milk passed to the outside?
Definition
compound alveolar glands pass milk to lactiferous ducts
Term
What is oogenesis?
Definition
production of female sex cells by meiosis
Term
Oogenesis: Step 1
Definition
In the fetal period, oogonia(2n ovarian stem cells) multiply by mitosis and store nutrients
Term
Oogenesis: Step 2
Definition
Primordial follicles appear as oognoia are transformed into primary oocytes
Term
Oogenesis: Step 3
Definition
Primary oocytes begin meiosis but stall in prophase I
Term
Oogenesis - Puberty: Step 1
Definition
One activated primary oocyte produces two haploid cells
Term
What are the two haploid cells produced by the activated primary oocyte?
Definition
polar body and secondary oocyte
Term
Oogenesis - Puberty: Step 2
Definition
Secondary oocyte arrests in metaphase II and is ovulated
Term
Oogenesis - Puberty: Step 3
Definition
If penetrated by sperm second oocyte completes meiosis II
Term
What are teh two products yielded after sperm penetration and meiosis II completion?
Definition
One large ovum (functional gamete), tiny second polar body
Term
Phases of Meiosis
Definition
Interphase, Prophase I, Metaphase I, Anaphase I, Telophase I, Meosis II
Term
Interphase
Definition
Two nuclear divisoins halve the number of chromosomes. Chromosomes replicate prior to meiosis I
Term
Prophase I
Definition
Homologus chromosomes undergo synapsis, Tetrads are formed with homologus partners. Crossing over takes place during prophase I
Term
Metaphase I
Definition
tetrads line up at the spindle equator during metaphase I
Term
Anaphase I
Definition
homologous chromosomes composed of joined sister chromatids are distributed to opposite ends of the cells
Term
Telophase I
Definition
nuclear membrane forms around chromosomal masses. Spindle break down. Chromatin reappears.
Term
What are the products after telophase and cytokinesis being completed?
Definition
two haploid daughter cells with 2n amount of DNA
Term
Difference between meiosis I and meiosis II?
Definition
chromosomes do not replicate prior to meiosis II
Term
Products after meiosis II?
Definition
4 haploid daughter cells with n amount of DNA
Term
Establishing the Ovarian Cycle: Step 1
Definition
During childhood, ovaries grow and secrete small amounts of estrogens that inhibit the hypothalamic release of GnRH
Term
Establishing the Ovarian Cycle: Step 2
Definition
As puberty nears, GnRH is released; FSH and LH are released by pituitary, which act on ovaries
Term
Establishing the Ovarian Cycle: Step 3
Definition
Step 2 repeats until an adult cyclic pattern is achieve and menarche occurs
Term
Hormonal Interactions During the Ovarian Cycle: Step 1
Definition
Day 1, GnRH stimulates the release of FSH and LH
Term
Hormonal Interactions During the Ovarian Cycle: Step 2
Definition
FSH and LH stimulate follicle growth and maturation, and low-level estrogen release
Term
Hormonal Interactions During the Ovarian Cycle: Step 3
Definition
Rising estrogen levels inhibit the release of FSH and LH, prod the pituitary to synthesize and accumulate these gonadotropins
Term
Hormonal Interactions During the Ovarian Cycle: Step 4
Definition
Estrogen levels increase and high estrogen levels have a positive feedback effect on the pituitary, causing a sudden surge of LH
Term
Hormonal Interactions During the Ovarian Cycle: Step 5
Definition
LH spike stimulates the primary oocyte to complete meiosis I, and teh secondary oocyte continues onto metaphase II
Term
Hormonal Interactions During the Ovarian Cycle: Step 6
Definition
Dah 14 - LH triggers ovulation
Term
Hormonal Interactions During the Ovarian Cycle: Step 7
Definition
LH transforms the ruptured follicle into a corpus luteum, which produced inhibin, progesterone, and estrogen
Term
Hormonal Interactions During the Ovarian Cycle: Step 8
Definition
These hormones shut off FSH and LH production and release and declining LH ends luteal activity
Term
Hormonal Interactions During the Ovarian Cycle: Step 9
Definition
Days 26-28 declind of teh ovarian hormones. Ends the blockade of FSH and LH
Term
Hormonal Interactions During the Ovarian Cycle: Step 10
Definition
Cycle starts anew
Term
Menstrual Cycle: Days 1-5
Definition
menstrual phase, uterus sheds all but the deepest part of the endometrium
Term
Menstrual Cycle: 6-14
Definition
proliferative (preovulatory) phase - endometrium rebuilds itself
Term
Menstrual Cycle: 15-28
Definition
secretory (postovultatory) phase - endometrium prepares for implantation of the embryo
Term
If fertilization does not occur, what happens hormonally?
Definition
progesterole levels fall, depriving the endometrium of hormonal support
Term
If fertilization does not occur, what happens arterially?
Definition
arteries kink and go into spasms and endometrial cells begin to die
Term
If fertilization does not occur, what happens to the functional layer?
Definition
begins to digest itself
Term
If fertilization does not occur, what happens after the functional layer begins to digest itself?
Definition
arteries constrict one final time then suddenly relax and open wide
Term
What happens as a result of the arteries suddenly relaxing and opening wide?
Definition
rush of blood fragments weakened capillary beds and teh functional layer sloughs
Term
What are the accessory sex glands of the male reproductive system?
Definition
seminal vesicle, prostate gland, and bulbourethral glands
Term
What two sets of muscles keep intrascrotal temperature constant?
Definition
dartos, cremaster
Term
What is the dartos?
Definition
smooth muscle that wrinkles scrotal skin
Term
What is the cremaster?
Definition
bands of skeletal muscle that elevate the testes
Term
What are the tunics of the testes?
Definition
vaginalis, albuginea
Term
What is the tunica vaginalis?
Definition
derived from the peritoneum
Term
What is the tunia albuginea?
Definition
fibrous capsule of the testis
Term
How many lobules are present in the testis?
Definition
250-300
Term
how many semineferous tubules are present in each lobule?
Definition
1-4
Term
What do the seminiferous tubules converge to form?
Definition
tubulus rectus
Term
What do the seminiferous tubules produce?
Definition
sperm
Term
What conveys sperm to the rete testis?
Definition
straight tubulus rectus
Term
How do the sperm leave teh rete testis?
Definition
efferent ductules
Term
After leaving the rete testis where do the sperm go?
Definition
enter the epididymis
Term
What surround the seminiferous tubules?
Definition
Interstitial cells
Term
What do the intersitial cells around the seminiferous tubules produce?
Definition
androgens
Term
What is the role of the spermatic cord?
Definition
encloses PNS and SNS nerve fibers, blood vessels, and lymphatics that supply the testes
Term
What is the corpus spongiosum?
Definition
surrounds the urethra and expands to form the glans and bulb of the penis
Term
what is the corpora cavernosa?
Definition
paired dorsal erectile bodies bound by fibrous tunica albuginea
Term
WHat is the crura?
Definition
proximal end of the penis surrounded by the ischocavernosus muscle; anchors the penis to the pubic arch
Term
The head of what joins the efferent ductules and caps teh superior aspect of the testis?
Definition
epididymis
Term
The duct of the epididymis contains sterocilia that do what?
Definition
absorb testicular fluid, pass nutrients to the sperm
Term
How do sperm become motile?
Definition
by passing through the tubes of the epididymis
Term
Upon ejactulation the epididymis, expelling sperm into what?
Definition
ductus deferens
Term
What runs from the epididymis through the inguinal canal into the pelvic cavity?
Definition
ductus deferens
Term
THe terminus of teh ductus deferens expands to form what?
Definition
ampulla
Term
THe ampulla joins the duct of the seminal vesicle to form what?
Definition
ejaculatory duct
Term
The role of teh ductus deferens and ejaculatory duct is?
Definition
propel sperm from the epididymis to the urethra
Term
What are the three regions of the male urethra?
Definition
prostatic, membranous, spongy/penile
Term
WHat is the prostatic urethra?
Definition
portion surrounded by the prostate
Term
What is the membranous urethra?
Definition
lies in the urogential diaphragm
Term
What is teh spongy/penile urethra?
Definition
runs through the penis and opens to the outside at the external urethral orifice
Term
Where are teh seminal vesicles located?
Definition
posterior wall of the bladder
Term
What is the role of the the seminal vesicles?
Definition
secrete 60% of teh volume of semen
Term
Sperm and seminal fluid mix in where before entering the prostatic urethra during ejaculation?
Definition
ejaculatory duct
Term
What is the prostate gland's role in relation to sperm?
Definition
role in activation
Term
What prevents the mixture of urine and semen?
Definition
the prostage gland
Term
What is the role of the bulbourethreal glands in males?
Definition
produce thick, clear mucus prior to ejaculation that neutralizes traces of acidic urine in the urethra
Term
What is the role of prostaglandinds in semen?
Definition
facilitate movement of sperm through the female reproductive tract by decreasing the viscosity of mucus in the cervix, stimulate reverse peristalsis in the uterus
Term
Why is semen alkaline?
Definition
neutralizes the acid environment found in the male urethra and female vagina
Term
What is spermatogenesis?
Definition
sequence of events that produces sperm in the seminiferous tubules of the testes
Term
Sperm formation: Step 1
Definition
Mitosis of spermatogonia, forming spermatocytes
Term
Sperm formation: Step 2
Definition
Spermatocytes go through meiosis to form spermatids
Term
What is spermiogenesis?
Definition
formation of sperm from spermatids
Term
What are spermatognoia?
Definition
outermost cells in contact with the epithelial basal lamina
Term
WHen does spermatogenesis begin?
Definition
at puberty
Term
What does each mitotic deivision of spermatogonia result in?
Definition
type A or type B daughter cells
Term
What are type A daughter cells?
Definition
remain at the basement membrane and maintain the germ line
Term
What are type B daughter cells?
Definition
move toward the lumen and become primary spermatocytes
Term
What happens to primary spermatocytes?
Definition
undergo meiosis I
Term
What is formed after spermatocytes undergo meiosis I?
Definition
two haploid cells called secondary spermatocyes
Term
What happens to secondary spermatocytes?
Definition
undergo meiosis II, daughter cells are called spermatids
Term
What is spermiogenesis?
Definition
spermatids lose excess cytoplasm and form a tail; becoming sperm
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