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Chapter 25
Metabolism
78
Anatomy
Undergraduate 4
11/11/2007

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Term

The breakdown of organic molecule to obtain energy is known as

Definition
Catabolism
Term

For energy to be created, you need 3 things

Definition

Oxygen

Water

Nutrients

Term
Essential functions of cellular metabolism includes
Definition

Growth and Cell Division

Secretion

Contraction

Term
The two major compontents of metabolism are
Definition
CATABOLISM and ANABOLISM
Term
Glycogen is the most abundant storage of energy compounds whcih is from the breakdown of _________
Definition
Carbohydrate
Term
___________ are most abundant storage from lipds and fatty acids.
Definition
Tryglycerides
Term
THE most abundant organic compound in the body is/are ________
Definition
PROTEINS!
Term

In Glycolysis, Glucose is broken down into smaller molecules to be used by ________ of the cells

Definition
MITOCHONDRIA
Term
ANEROBIC breaksdown glucose into ____________.
Definition
Pyruvic Acid
Term
Shin Splints are a result of pyruvic acid becoming _______  ________  which builds up in your body.
Definition
Lactic Acid
Term
If oxygen is present, mitochondria absorb & breakdown pyruvic acid in a process called
Definition
AEROBIC reaction or metabolism
Term
There are 4 methods of producing ATP
Definition

1. TCA Cycle

2. Oxydative Phosphorylation

3. Oxidation

4. ETS (Electron Transport System)

Term
When Carbon and Oxygen atoms are removed and released as CO2, this process is called
Definition
Decarboxylation
Term
The function of the TCA cycle is
Definition
to remove H+ atoms from pyruvic acid to produce citric acid, A.K.A. Kreb's Cycle
Term
In the TCA cycle, just know that WATER is produced, H+ ions are given off, and CO2 is a waste product
Definition
The product of ONE TCA cycle is = 1 molecule of GTP which becomes ATP
Term
The generation of ATP within Mitochondria which requires Hydrogen, Oxygen and Coenzymes is called ________________
Definition
Oxydative phosphorylation
Term
Oxydative Phosphorylation produces ____% of the body's ATP.
Definition

90%

Term
The ETS (Electron Transport System) is the key reaction in Oxy Phos which occurs in the mitochondrial membrane.  Its also called _______
Definition
The respiratory chain
Term
this mean Loss of Electrons
Definition
Oxydation
Term
This means gain of electrons
Definition
Reduction
Term
Electrons transfer Energy via ____________ ions
Definition
HYDROGEN IONS
Term
_________ act as intermediaries by accepting and transferring molecules in Oxdiation-Reduction reactions.
Definition
Coenzymes
Term
What does ETS do?
Definition
It "assists only" in ATP production by creating a steep concentration gradient across the mitochondrial membran.   The electrons release energy when transferred assiting to make ATP
Term
The most important mechanism for generation of ATP is
Definition
Oxydative Phosphorylation
Term
_________ is the breakdown of glycogen to glucose
Definition
Glycogenolysis
Term
___________ is the formation of glycogen from glucose
Definition
Glucogenesis
Term
Lipid molecules contain 3 things:
Definition

Carbon

Hydrogen

Oxygen

Term
The most ABUNDANT lipid in the body is/are __________
Definition
Triglycerides
Term
When you break down a lipid, you get __________ & __________
Definition
Glycerol and fatty acids
Term
Ok, now once you have your Glycerol and Fatty Acids, you can convert those to __________ via the TCA cycle.
Definition
Pyruvic Acid
Term
The conversion of Fatty Acids into Acetyl-CoA is called
Definition
BETA OXYDATION
Term
Lipid Synthesis is also called
Definition
Lipogenesis
Term
Acetyl-CoA helps synthesize _________
Definition
Lipids
Term
____ ____ acids are lipds that can easily cross cell membranes, and are usually bound to albumin in the blood.  They are the most ABUNDANT plasm protein.
Definition
FREE FATTY ACIDS
Term
5 types of LIPOPROTEINS
Definition

CHYLOMICRONS

VDLs

IDLs

LDLs

HDLs

Term

LDLs (lousy) drop off cholesterol to the periphery. They 're like the litterbugs of cholesterol.

 

HDLs pick it up from the periphery and bring it to the liver for metabolization.   They're like the trash-picker-uppers.

Definition

The body synthesizes 100,000 to 140,000 kinds of protiens.   Name them.   

 

Actually about 20 amino acids build all proteins.

Term
Deanimation is the process of breaking down _______ ______ in the TCA cycle
Definition
Amino Acids
Term

The bonds between TWO amino acids are known as

Definition
Peptide Bonds
Term
In Amino acid catabolism, pyridoxine is required.... otherwise known as
Definition
VITAMIN B6
Term
Keytones in the urine means
Definition

lack of protein breakdown

Term
Name 3 negatives in Protein Catabolism
Definition

1. Proteins are more difficult to break down

2. Ammonium ions are a toxic biproduct

3. Protiens are needed for cell structure

Term

In protein synthesis, the body synthesizes 50% of the amino acids needed to build proteins.   NON-essential amino acids are made by the body on demand.

Definition

Get up and stretch!

Term
The main focal point of metabolic regulation is this organ
Definition
The LIVER
Term

Know the following about what they do:

 

Adipose Tissue stores lipids which are brokent down when glucose is low.

 

Liver cells regulate nutrient levels in blood

Definition

Neural tissue has no nutrient reserves and needs constant glucose.

 

CNS needs glucose or you become unconscious.

 

 

Term
Body has 2 patterns of daily metabolic activity:  ABSORPTIVE AND POST ABSORPTIVE...... What is the difference?  (test question)
Definition

Absporptive is period following a meal where NUTRIENT absorption is undeway.

 

PostAbsorptive is where NO nutrient absportion happens and body relies on energy reserves for energy demands.

Term
Metabolic Activities are coordinated by these 4 things.....
Definition

Glucagon

Epinephrine

Glucocorticoids

Growth Hormone

Term
The appearance of keytone bodies in the bloodstream is known as
Definition
KETONEMIA
Term
A dangerous drop in blood PH caused by high keytone levels is called
Definition

Ketoacidosis

Term

In the postabsorptive state, ___________ in the liver maintains blood glucose reserves

Definition
gluconeogenesis
Term
The absorption of nutrients from food is known as
Definition
Nutrition
Term
Beef, Fish, Poultry, Eggs and Milk provide all the essential COMPLETE PROTEINS in the form of _______ ______
Definition
"amino acids"
Term
Incomplete proteins are found in
Definition
PLANTS                      which is a problem in vegetarian diets
Term
Nitrogen balance in the body is not stored.   Its obtained from diet and lost thru urine and feces.
Definition

Nitrogen is recycled in the body also to maintain balance

Term
A positive nitrogen balance is when ingestion ________ secretion
Definition

EXCEEDS                             its important in childhood growth

 

Term
What are the fat soluable vitamins again?
Definition
A D E K
Term
Inorganic ions released thru breakdown of electrolytes are otherwise known as
Definition
MINERALS
Term
Vitamin A is needed for
Definition
Retinal pigment (eyesight)
Term
Vitamin D is needed for
Definition
conversionto calcitriol which increases rate of intestinal calcium absorption........... BONES
Term
Vitamin E does what
Definition
Stabilizes intracellular membranes
Term
Vitamin K is for
Definition
Clotting factors
Term
Poor diet contributes to which diseases?
Definition

Obesity

Heart Disease

Hypertension

Diabetes

Artherosclerosis

Term
Vitamins stored in the body are FAT soluable.  Water soluable vitamins are rarely toxic and excreted in the urine.
Definition

Vitamin B12 is the ONLY vitamin that needs intrinsic factor before absorption

Term
When chemical bonds are broken, energy is __________
Definition
RELEASED
Term
What is calorimetry?
Definition
The measure of total energy released when bonds are broken down by digestion
Term
What is a Calorie?
Definition
Energy required to raise 1 kilogram of water 1 degree centigrade... this is a Calorie (C)
Term
What is the metabolic Rate?
Definition
Sume of all anabolic and catabolic processes in the body
Term
What is BMR?
Definition
Basal Metabolic Rate.... its the minimum resting energy expenditure of an awake and alert person.
Term
If your energy intake EXCEEDS your energy demands, what does the body do?
Definition

The body will store excess energy as triglycerides in adipose tissue. 

 

 

Energy NOT used is released as heat

Term
When adipose tissues are in an absorptive state, this hormone is released
Definition
Leptin
Term

THermoregulation is basically

Definition

heat exchange to mainatin environment

 

Term
This part of the brain is known as the HEAT REGULATORY CENTER
Definition

Anterior HYPOTHALMUS

Term
The heat-loss center does 3 actions:
Definition

1. inhibits vasomotor center causing vasodilation, skin temp rises

 

2. stimulate sweat glands

 

3.  stimulates respiratory centers

Term

Distinguish between insensible and sensible perspiration

Definition

Insensible is when water evaporates on skin surface naturally

 

Sensible is water from your sweat glands

Term
In heat dissipation, when the body wants to rid heat, the inner muscular veins ________ and the outer veins ________.
Definition
muscular veins constrict and the outer veins dilate
Term

2 methods of generating heat:

Definition

Shivering thermogenesis

 

Non-Shivering thermogenesis

Term
Non shivering takes longer as its a hormonal change in the body to generate heat.
Definition
Shivering can create 400% increase in heat
Term
Thermoregulation in infants is a problem.... why?
Definition

because babies lose heat quickly due to small size

 

temperature regulating mechanism is not fully functional

 

and best, INFANTS CAN NOT SHIVER

Term

You will get what grade on the test tomorrow?

Definition

A

 

believe it!

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