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Chapter 25
Metabolism and Energetics
25
Physiology
Undergraduate 2
02/18/2018

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Term
Metabolism
Definition
All the chemical reactions that take place in an organism
Term
Energetics
Definition
The study of the flow of energy and it's changes from one form to another
Term
Catabolism
Definition
The breakdown of organic molecules
Term
Anabolism
Definition
The synthesis of new organic molecules
Term
Cells synthesize new organic molecules for 4 reasons:
Definition
1. To carry out structural maintenance or repairs
2. To support growth
3. To produce secretions
4. To store nutrient reserves
Term
glycolysis
Definition
The breakdown of glucose to pyruvic acid
Term
Glycolysis requires:
Definition
1. Glucose molecules
2. Appropriate cytosolic enzymes
3. ATP and ADP
4. Inorganic phosphates
5. NAD (nicotinamide adenine dinucleotide)
Term
Citric acid cycle (tricarboxylic acid cycle, TCA, or Kreb's cycle)
Definition
A sequence of enzymatic reactions
Term
Function of the citric acid cycle
Definition
To remove hydrogen atoms from organic molecules and transfer them to coenzymes.
Term
Oxidative phosphorylation
Definition
The generation of ATP within mitochondria in a reaction sequence that requires coenzymes and consumes oxygen.
Term
gluconeogenesis
Definition
The synthesis of glucose from noncarbohydrate precursors
Term
glycogenesis
Definition
The formation of glycogen from glucose
Term
lipolysis
Definition
lipid catabolism
Term
Lipoproteins
Definition
Lipid-protein complexes that contain large insoluble glycerides and cholesterol
Term
5 groups of lipoproteins
Definition
1. Chylomicrons-largest, carry absorbed lipids from the intestinal tract into the lymph, then into the bloodstream
2. Very low density lipoproteins (VLDLs)-transport triglycerides to skeletal muscle and adipose tissue
3. Intermediate density lipoproteins-intermediate in size and lipid composition
4.Low density lipoproteins (LDLs)- deliver cholesterol to peripheral tissues
5. High-density lipoproteins (HDLs)-equal amounts lipid and protein, transport excess cholesterol from peripheral tissues back to the liver for storage or excretion in the bile
Term
Transamination
Definition
Attaches the amino group of an amino acid to a keto acid
Term
Deamination
Definition
The removal of an amino group and a hydrogen atom in a reaction that generates an ammonium ion (NH4+)
Term
Ketone body
Definition
An organic compound produced by fatty acid metabolism that dissociates in solution, releasing a hydrogen ion.
Term
Nutrition
Definition
The absorption of nutrients from food
Term
3 reasons minerals are important:
Definition
1. Ions such as sodium and chloride determine the osmotic concentrations of body fluids.
2. Ions in various combinations play major roles in important physiological processes.
3. Ions are essential cofactors in a variety of enzymatic reactions.
Term
Vitamin
Definition
An essential organic nutrient that functions as a coenzyme in vital enzymatic reactions
Term
Calorie
Definition
The amount of energy needed to raise the temperature of 1 kilogram of water 1 degree Celcius.
Term
Obesity
Definition
Body weight more than 20% above the ideal weight for a given individual
Term
Basal metabolic rate (BMR)
Definition
The minimum resting energy expenditure of an awake, alert person
Term
Mechanisms for increasing heat loss
Definition
1. The inhibition of the vasomotor center causes peripheral vasodilation, and warm blood flows to the surface of the body.
2. As blood flow to the skin increases, sweat glands are stimulated to increase their secretory output.
3. The respiratory centers are stimulated, and the depth of respiration increases.
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