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a layer of cortical neurons lying below the cortical plate early in development; when the cortical plate has differentiated into the six layers of the neocortex, the subplate disappears |
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a glial cell in the emryonic brain extending a process from the ventricular zone to the surface of the brain; immature neurons and glia migrate along this process |
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an immature neuron before cell differentiation |
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a cell layer of the immature cerebral cortex containing undifferentiated neurons |
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the specialized tip of a growing neurite |
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the network of fibrous proteins deposited in the space between cells |
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a process in which axons growing together stick to one another |
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cell-adhesion molecule (CAM) |
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a molecule on the cell surface that causes cells to adhere to one another |
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a diffusible molecule that acts over a distance to attract growing axons |
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an axonal guidance module; a protein secreted by cells in specific locations in the developing CNS that can act as either an axonal attractant or a repellent, depending on the type of netrin receptor expressed on the growing axon |
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a diffusible molecule that acts over a distance to repel growing axons |
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the hypothesis that chemical markers on growing axons are matched with complementary chemical markers on their targets |
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a protein secreted by neurons in many parts of the developing nervous system that helps establish topographic axonal connections |
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nerve growth factor (NGF) |
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long-term potentiation (LTP) |
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long-term depression (LTD) |
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