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Chapter 23
Diseases of Cardiovascular and Lymphatic system
31
Microbiology
Undergraduate 1
04/24/2011

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Term
sepsis
Definition
inflammatory response caused by the spread of bacteria or their toxin from a focus of infection.
Term
septicemia
Definition
sepsis that involves proliferation of pathogens in the blood.
Term
sepsis result of what?
Definition
an infection associated inflammatory mediators being released into the blood, although the source of the etiology is not necessarily in the blood
Term
symptoms of sepsis
Definition
fever and chills, rapid heart rate or respiratory rates, drop in blood pressure, organ faliure, elevated white blood cell count, release of iron from RBCs by microbial action cn stimulate iron growth
Term
lymphangitis
Definition
red streaks up the appendages indicative of inflamed lymph vessels, often associated with sepsis of septicemia.
Term
gram-negative sepsis
Definition
can lead to severe sepsis, characterized by decreased blood pressure. endotoxin causes the symptoms. when the blood pressure cannot be controlled it is the septic shock.
Term
burcellosis other name
Definition
undulant fever
Term
burcellosis facts
Definition
most common bacterial zoonosis. 500,000 new human cases a year. middle east is endemic region. also common to Mediterranean and SE European region, latin american and caribbean.
Term
brucella abortus
Definition
cattle
Term
brucella melitensis
Definition
goats and sheep- most common and most dangerous to humans
Term
B. suis
Definition
swine
Term
brucella bactera characteristics
Definition
small, aerobic gram negative coccoid rod shaped bacterium.
Term
burcellosis transmission
Definition
by inhalation, ingestion or break in skin. highly infectious, dangerous to handl and easily aerosolized and highly transmissible.
Term
signs of burcellosis
Definition
malaise, night sweats, muscle aches and fever that spikes each evening (undulant fever); incubation period is 1-3 weeks.
Term
bubonic plague transmission
Definition
a disease of rodents, transmittied by the bite of a flea. when rodents die, fleas feed on closest available mammal. man is an accidental host of the bubonic plague
Term
plague bacteria characteristics
Definition
plague; gram negative facultative bacterium
Term
buboes
Definition
swollen lymph nodes, usually in groin or under arms, extremely painful. the skin becomes darkened and black due to hemorrhaging.
Term
pneumonic plague symptoms
Definition
respiratory transmission; once human is final stages of plague, follow a septicemic stage that itself is often fatal. pink frothy blood comes out of the noes and mouth when coughing
Term
lyme disease facts
Definition
most common tickborne disease in US. first appeared in 1975 as a cluster of disease cases in young adults. 1983 a spirochete later was identified as etioogical agent (borrelia burgdorferi)
Term
reservoir of lyme disease
Definition
field mice are most important; deer also for maintaining the disease, though less likely to harbor the ticks most likely to carry disease
Term
symptoms of lyme disease
Definition
rash at bite site and expands; flu like symptoms in 2-3 weks as rash fades.
Term
second phase of lyme disease
Definition
if not treated. heart involvemtn, irregular heartbeat, chronic neurological symptoms, incapacitation, facial paralysis, meningitis, encephalitis
Term
third phase of lyme disease
Definition
months or years after infection, arthritis in some patients, similar long term effects as syphilis
Term
signs and symptoms of malaria
Definition
chills fever vomiting and headache at intervals of 2-3 days
Term
transmission of malaria
Definition
by mosquitoes. agent is one of four species of plasmodium
Term
four forms of malaira
Definition
P. vivax, P. ovale, P. malariae and P. falciparum
Term
P. vivax
Definition
benign malaria; widely distributed due to fact that it can develop at lower temps in mosquito- most prevalent form of disease
Term
P. ovale and P. malariae
Definition
relatively benign, restricted geographically
Term
P. falciparum
Definition
most dangerous form; left untreated mortality 50%. children most susceptible to death; high degree of RBC cell lysis, thus anemia is significant.
Term
prevention of malaria
Definition
mosquito control and mosquito netting
Term
prophylaxis
Definition
cloroquine, malarone
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