Term
| What are the two intrinsic systems of the immune system |
|
Definition
|
|
Term
| What is the nonspecific defense system |
|
Definition
|
|
Term
| What is the specific defense system |
|
Definition
|
|
Term
| What does immunity refer to |
|
Definition
|
|
Term
| What are the 2 lines of defense in the Innate defense system |
|
Definition
First line of defense= Skin and Mucosae
Second line of defense=Antimicrobial proteins, phagocytes and other cells |
|
|
Term
| What are the 2 functions of the second line of defense |
|
Definition
Inhibit spread of invaders
Inflammation is the most important mechanism |
|
|
Term
| What is the third line of defense attack? Specific or non-specific? |
|
Definition
attacks particular foreign substances
Very specific. |
|
|
Term
| What system takes longer to react? Innate or Adaptive |
|
Definition
|
|
Term
| What type of cells are involved in our adaptive system? |
|
Definition
|
|
Term
| What are T-Cells involved with? |
|
Definition
|
|
Term
| what are B-Cells involved in |
|
Definition
| Humoral (antibody)response |
|
|
Term
| Innate and adaptive defenses are deeply __________ |
|
Definition
|
|
Term
Non Specific, No Memory
What is this describing |
|
Definition
|
|
Term
| What 5 things are involved in our internal Innate defense system? |
|
Definition
| Phagocytes, Natural Killer (NK)Cells Inflammation, Antimicrobial Proteins, Fever. |
|
|
Term
| What are the surface barriers |
|
Definition
| Skin, Mucous membranes, and their Secretions |
|
|
Term
| Function of Surface barriers |
|
Definition
| Surrace barriers act as a physical barrier to most microorganisms |
|
|
Term
| What does keratin's function |
|
Definition
| Keratin is resistant to weak acids and bases, baccterial enzymes, and toxins |
|
|
Term
| What are some protective chemicals that inhibit or destroy microorganisms |
|
Definition
skin Acidity
Lipids in sebum
Dermcidin in sweat
HCL and protein digesting enzymes of stomach mucosae
Lysozyme of saliva and lacrimal fluid destroy bacteria
Mucus catches dust |
|
|
Term
| What are some respiratory specific modifications? |
|
Definition
Mucus coated nose hairs
Cilia of upper respiratory tract |
|
|
Term
| What is the function of the cilia in the upper respiratory tract? |
|
Definition
| sweep dust and bacteria laden mucus from lower respiratory passages |
|
|
Term
| What necessitates Internal Defenses to be activated |
|
Definition
| If microorganisms invade deeper tissues than the skin. |
|
|
Term
| What are two examples of phagocytes |
|
Definition
| Macrophages and neutrophils |
|
|
Term
| What do Natural Killer cells attack |
|
Definition
| Virus infected cells and cancer cells |
|
|
Term
| What are involved in the inflammatory response |
|
Definition
| Macrophages, mast cells, wBCs, and inflammatory chemicals |
|
|
Term
| What are two antimicrobial proteins |
|
Definition
| Interferons and complement proteins |
|
|
Term
| What are macrophages function |
|
Definition
| they are general Scavengers |
|
|
Term
| What are Neutrophils function |
|
Definition
| they become phagocytic when encountering infectious material |
|
|
Term
|
Definition
|
|
Term
| What is Eosinopils function |
|
Definition
| they are weakly phagocytic against parasitic worms |
|
|
Term
| What are mast cells function |
|
Definition
| they bind and ingest a wide range of bacteria. |
|
|
Term
| What do Basophils secrete |
|
Definition
| Histamines which cause inflammation to occur |
|
|
Term
| What do macrophages develop from |
|
Definition
|
|
Term
| What type of macrophages wander through tissue spaces? Example |
|
Definition
Free macrophates
Alveolar macrophages |
|
|
Term
| what kind of macrophages are permanent residents of some organs? Example and location |
|
Definition
Fixed Macrophates
Kupffer cells (liver)
Microglia (Brain) |
|
|
Term
|
Definition
| False Feet. Cytoplsmic extententions uset to pull bacteria toward itself for ingesting |
|
|
Term
| When do Neutrophils become phagocytic? |
|
Definition
| When they encounter infectious material in tissues |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Dendritic (Langerhan cells) loc |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
All tissues including
Spleen
Lymph nodes
Liver
lung
Skin |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| the coating of pathogen by complement proteins or antibodies |
|
|
Term
| What is the particle that is going to be engulfed called |
|
Definition
|
|
Term
| What is the vessel inside a phagocyte that contains the antigen called |
|
Definition
|
|
Term
| What is it called when a phagosome fuses with a lysosome |
|
Definition
|
|
Term
| What ultimately digest the antigens in the phagolysososmes |
|
Definition
|
|
Term
| What is the proccess in which a phagolysosome removes its digested antigens called |
|
Definition
|
|
Term
| What do lysosomes contain |
|
Definition
| Hydrolytic enzymes that degrade bacteria |
|
|
