Term
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Definition
| The use of drugs to treat a disease |
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Term
Interferes with the growth of microbes |
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Definition
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Term
A substance produced by a microbe that in small amounts, inhibits another microbe |
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Definition
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Term
| A drug that kills harmful microbes without damaging the host |
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Definition
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Term
Who discovered penicillin which is produced by penicillium |
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Definition
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Term
| What 2 people performed the first clinicial trials of penicillin? |
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Definition
1) Howard Florey 2) Emst Chain |
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Term
| What are the 5 actions of antimicrobrial drugs within a cell? |
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Definition
Inhibit cell wall synthesis inhibit protein synthesis injury to plasma membrane inhibit of synthesis of essential metabolism inhibit nucleic acid, replication, transcription
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Term
| What antimicrobrial drug binds to 50s portion and inhibits formation of peptide bond? |
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Definition
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Term
| What antimicrobial drug changes shape of 30s portion causes code on mRNA to be read incorrectly |
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Definition
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Term
| What antimicrobial drug interferes with the attachment of tRNA to mRNA-ribosome complex |
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Definition
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Term
What are two types of Penicillin? |
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Definition
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Term
2nd, 3rd, 4th generations are more effective against gram-negatives |
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Definition
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Term
What are 2 polypeptide antibiotics? |
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Definition
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Term
Topical application against gram positives
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Definition
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Term
| What are 2 natural penicillin? |
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Definition
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Term
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Definition
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Term
| What are 2 antimycobacterial antibiotics? |
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Definition
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Term
What are some antibacterial antibiotics that inhibit cell wall synthesis? |
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Definition
Penicillin Cephalosporins Bacitracin Vancomycin Isoniazid ethambutol
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Term
Inhibits protein synthesis Broad spectrum - binds 50 s subunit, inhibits peptide bond formation |
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Definition
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Term
Inhibits protein synthesis streptomycin, neomycin, gentamycin broad spectrum - changes shape of 30S subunit |
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Definition
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Term
Inhibits Protein Synthesis Broad spectrum - interferes with tRNA attachment |
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
| Name antibacterial antibiotics that inhibit protein synthesis |
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Definition
Chloramphenicol aminoglycosides tetracyclines streptogramins macrolides oxazolidinones
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Term
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Definition
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Term
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Definition
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Term
Inhibits nucleic acid synthesis |
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Definition
ciproflaxacin inhibits DNA gyrase Urinary tract infections |
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Term
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Definition
| Sulfonamides (sulfa drugs) |
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Term
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Definition
antibimicrobial drug that effects a broad range of gram + and gram - bacteria. |
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Term
What is a superinfection? |
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Definition
| It is a growth of a target pathogen that becomes resistant to antibiotics so infection continues |
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Term
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Definition
They kill microbes directly |
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Term
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Definition
| Inhibits the growth of microbes |
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Term
what are 2 aminoglycosides? |
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Definition
| streptomycin, neomycin, gentamycin |
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