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Chapter 1
General Pharmacologic
22
Pharmacology
Professional
12/30/2010

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Term
Pharmacology
Definition
The study of drugs and thier action on the body.
Term
Therapeutics
Definition
Study of drugs used to cure, treat, or prevent disease.
Term
Pharmacotherapy
Definition
Application of drug therapy to disease treatment.
Term
Additive
Definition
Two drugs whose sum effect when given together is equal to the effect from each given separately but at the same time.
Term
Agonist
Definition
Drug that activates its receptor upon binding
Term
Antagonist
Definition
Drug that binds to its receptor without acivating it
Term
Bioavailability
Definition
Fraction of drug dose that reaches the systemic circulation
Term
Dependence
Definition
Drug use that may result in withdrawal symptoms upon discontinuation; symptoms can be psychologic or physiologic.
Term
Desensitization
Definition
Loss of tissue responsiveness that can occur with drug exposure
Term
Disease management
Definition
All-inclusive management of a patient's disease
Term
Emetics
Definition
Agents that induce vomiting
Term
Enteral Route
Definition
The route comprising oral, sublingual, nasogastric, or rectal routes of drug absorption
Term
First-pass effect
Definition
Elimination of drug that happens after administration but before it reaches the systemic circulation
Term
Formulary
Definition
List of drugs stocked by the pharmacy.
Term
Half-life
Definition
Time it take for the drug concentration to fall 50% in the body
Term
Maintenance dose
Definition
Dose given to keep a drug at a therapeutic level in the blood
Term
Loading dose
Definition
Starting dose that is administered to achieve a therapeutic concentration rapidly.
Term
Parenteral route
Definition
The route comprising routes that bypass the alimentary tract; injectable
Term
Pharmacodynamics
Definition
Actions of the drug on the body
Term
Pharmacokinetics
Definition
Actions of the body on the drug
Term
Potentiation
Definition
The effect of two drugs given together when one drug has no effect but increases the response of the other drug, which normallyhas a lesser effect.
Term
Protein binding
Definition
Refers to sites such as albumin where the drug is connected or bound and inactive; influences drug distribution
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