Term
Circulatory System: Two sub systems |
|
Definition
Cardiovascular system, Lymphatic system. |
|
|
Term
Cardiovascular System: Overview |
|
Definition
Blood, Heart, Blood Vessels. |
|
|
Term
|
Definition
Heart to Arteries, to Capillaries, to veins, to Heart. |
|
|
Term
Blood Circulation: At Capillaries |
|
Definition
Nutrients and O2 exit bloodstream, CO2 and cellular waste enter bloodstream. |
|
|
Term
|
Definition
Connective tissue, 2 main components- cellular, liquid. |
|
|
Term
Blood is ...% of body mass? |
|
Definition
|
|
Term
Men have...L and women have...L of blood in them. |
|
Definition
|
|
Term
|
Definition
Plasma, Hematocrit, Formed elements (buffy coat, erythrocytes) |
|
|
Term
|
Definition
Leukocytes, Thrombocytes. |
|
|
Term
Hematocrit (erythrocytes) % of whole blood in men and women |
|
Definition
Men: 47 +/- 5%, Women: 42 +/- 5% |
|
|
Term
|
Definition
90% water, 10% of other molecules (>100) |
|
|
Term
Plasma: Composition of other molecules |
|
Definition
Ions, Nutrients, Hormones, Vitamins, Oxygen, Wastes, Proteins. |
|
|
Term
|
Definition
|
|
Term
|
Definition
Amino acids, simple sugars, lipids. |
|
|
Term
|
Definition
Carbon dioxide, ammonia, urea. |
|
|
Term
|
Definition
Albumin, globulins, fibrinogen. |
|
|
Term
|
Definition
Keeps water in bloodstream |
|
|
Term
|
Definition
Transport of iron, copper, and lipids. |
|
|
Term
|
Definition
Plasma protein involved in blood coagulation. |
|
|
Term
Formed elements (blood cells) types of cells |
|
Definition
Erythrocytes, platelets, leukocytes. |
|
|
Term
Formed elements: Overview |
|
Definition
Originate in bone marrow, short life span. |
|
|
Term
Erythrocytes (RBCs) Size and shape |
|
Definition
|
|
Term
Erythrocytes are good.... |
|
Definition
|
|
Term
Erythrocytes is the ..... formed element. There are ... in adults? |
|
Definition
Most numerous, 25 trillion |
|
|
Term
Erythrocytes: There are no ... or ... |
|
Definition
|
|
Term
Erythrocytes are surrounded by a... |
|
Definition
|
|
Term
Erythrocytes: Cytoplasm contains... |
|
Definition
|
|
Term
Erythrocytes: ...% of erythrocytes that is not water is... |
|
Definition
|
|
Term
Erythrocytes: There are ...chains per hemoglobin molecule |
|
Definition
|
|
Term
Erythrocytes: Each amino acid chain has an... binding site for ... |
|
Definition
|
|
Term
Erythrocytes: Hemoglobin also carries...% of the ... that's carried in the blood. |
|
Definition
|
|
Term
Leukocytes (WBC's) Shape and number of them |
|
Definition
Spherical, less numerous than RBC's |
|
|
Term
|
Definition
|
|
Term
Leukocyte: Function in loose connective tissues |
|
Definition
Attracted by chemicals in areas of infection, Diapedesis (leaping through), Amoeboid motion. |
|
|
Term
|
Definition
Releases WBC's continuously into the blood, stores and releases WBC's in large quantities during infections. |
|
|
Term
Leukocytes: 2 classes of WBC's |
|
Definition
Granulocytes, Agranulocytes |
|
|
Term
Leukocytes: Granulocytes types |
|
Definition
Neutrophils, Eosinophils, Basophils. |
|
|
Term
Granulocytes: Composition |
|
Definition
|
|
Term
Granulocytes: Life span and size |
|
Definition
Shorter lived and larger than RBC's |
|
|
Term
|
Definition
Phagocytic, and polymorphonuclear. |
|
|
Term
Leukocytes: Agranulocytes types |
|
Definition
Lymphocytes and monocytes. |
|
|
Term
Leukocytes: Agranulocytes composition |
|
Definition
Absence of obvious granules |
|
|
Term
Neutrophils: Nomenclature |
|
Definition
|
|
Term
Neutrophils are the ... WBC |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
membrane sacs with digestive enzymes. |
|
|
Term
|
Definition
Consume and destroy bacteria, 1st line of defense vs infection, phagocytosis. |
|
|
Term
|
Definition
Dead neutrophils, other leukocytes, tissue debris, and dead bacteria. |
|
|
Term
Eosinophils: % of all leukocytes |
|
Definition
|
|
Term
|
Definition
Found in the wall of the digestive tube. |
|
|
Term
|
Definition
|
|
Term
|
Definition
contain digestive enzymes |
|
|
Term
Eosinophils: 2 things it responds to |
|
Definition
Allergic reactions, parasitic infections. |
|
|
Term
Eosinophils: Allergic reaction |
|
Definition
Phagocytosis of allergens: consumes allergens, degrade histamine, stop reaction. |
|
|
Term
Eosinophils: Parasitic infections |
|
Definition
Attach to parasites, release enzymes, digest and destroy. |
|
|
Term
Basophils make up what % of all leukocytes. |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
contain histamine and molecules secreted to mediate inflammation. |
|
|
Term
Basophils respond to two different things |
|
Definition
Allergic and Parasitic responses |
|
|
Term
|
Definition
early stages of inflammation |
|
|
Term
|
Definition
later stages of inflammation |
|
|
Term
Lymphocytes make up what % of all leukocytes |
|
Definition
|
|
Term
Lymphocytes: Nucleus: Overview and what's it filled with. |
|
Definition
Occupies the majority of the cell, filled with chromatin. |
|
|
Term
Lymphocytes: Nucleus: Shape |
|
Definition
|
|
Term
Lymphocytes: Nucleus: Surrounded by... |
|
Definition
|
|
Term
Lymphocytes are classified by? |
|
Definition
|
|
Term
Lymphocytes: Function in connective tissue |
|
Definition
Lymphoid, role in immunity. |
|
|
Term
Lymphocytes are the...cells of the.... |
|
Definition
|
|
Term
Lymphocytes: Immune function |
|
Definition
each acts against specific foreign molecule. |
|
|
Term
|
Definition
Any molecule inducing response from leukocyte. |
|
|
Term
Lymphocytes: 3 types of cells |
|
Definition
T cells, B cells, Natural killer cells. |
|
|
Term
|
Definition
Cytotoxic (aka killer, CD8+ T lymphocyte) cells attack directly, bind to antigen-bearing cells, punch holes in membrane, cause cell death. |
|
|
Term
Lymphocytes: T cells targets |
|
Definition
Target "alien" cells that have nucleus, organelles. |
|
|
Term
|
Definition
Differentiate into plasma cells that produce antibodies which bind to antigens and "flag" them for phagocytosis. |
|
|
Term
Lymphocytes: B cells target |
|
Definition
|
|
Term
Lymphocytes: Natural killer cells |
|
Definition
Rapid attack before entire immune response is generated. |
|
|
Term
Monocytes make up what % of WBC's? |
|
Definition
|
|
Term
|
Definition
Typically horseshoe or kidney shaped. |
|
|
Term
Monocytes: Is more ... than ... |
|
Definition
|
|
Term
|
Definition
Can contain tiny granules. |
|
|
Term
Monocytes: Once they go into... they transform into ... |
|
Definition
Connective tissue, macrophages |
|
|
Term
Monocytes: In CT characteristics. |
|
Definition
Phagocytic, move by amoeboid motion, ingest foreign cells, molecules, tiny debris particles. |
|
|
Term
Complete Blood Count: What it checks for |
|
Definition
Hematocrit, hemoglobin, concentration ((per cubic mm) erythrocytes, leukocytes, platelets.) |
|
|
Term
Complete Blood Count: What it is |
|
Definition
A blood test. Complete blood count with differential examines structural abnormalities. |
|
|
Term
|
Definition
Thrombocytes (clotting cells) |
|
|
Term
Platelet: Shape and composition |
|
Definition
Disc-shaped fragments with plasma membrane |
|
|
Term
|
Definition
|
|
Term
Platelet: Limit bleeding, what it does |
|
Definition
Plug tears in vessel walls, signal secretory granules, and to release thromboplastin for clotting. |
|
|
Term
Platelets: Secretory granules signaled for |
|
Definition
more platelets, vessel constriction, and to initiate inflammation. |
|
|
Term
|
Definition
Fibrin, platelets, trapped blood cells. |
|
|
Term
|
Definition
Clot that develops and stays (can block vessel) |
|
|
Term
|
Definition
|
|
Term
Formation of blood cells: Called |
|
Definition
|
|
Term
Formation of Blood Cells: Where and when it happens. |
|
Definition
Occurs in RED bone marrow, and continues throughout life. |
|
|
Term
Formation of Blood Cells: At birth... |
|
Definition
|
|
Term
Formation of Blood Cells: Location of RED bone marrow in adults. |
|
Definition
Axial skeleton, girdles, proximal epiphyses of humerus and femur. |
|
|
Term
Formation of Blood Cells: Cells in red marrow are... |
|
Definition
|
|
Term
Formation of Blood Cells: Mesenchymal stem cells give rise to... |
|
Definition
Fat cells, osteoblasts, chondrocytes, fibroblasts, and muscle cells. |
|
|
Term
Formation of Blood Cells: Yellow marrow contains... |
|
Definition
|
|
Term
Formation of Blood Cells: Yellow marrow only... |
|
Definition
makes blood cells in emergencies |
|
|
Term
Formation of Blood Cells: In adults, yellow marrow is located in.... |
|
Definition
All other regions of long bones. |
|
|
Term
|
Definition
Blood cell formation occurs in stages |
|
|
Term
Cell lines: All types of blood cells... |
|
Definition
arise from the blood stem cell |
|
|
Term
Cell lines: Two cell types |
|
Definition
Lymphoid and Myeloid stem cells. |
|
|
Term
Cell Lines: Lymphoid Stem Cells |
|
Definition
Give rise to lymphocytes. |
|
|
Term
Cell Lines: Myeloid Stem Cells |
|
Definition
Give rise to all other blood cells. |
|
|
Term
|
Definition
Polycythemia, Anemia, Sickle Cell Disease. |
|
|
Term
|
Definition
Excess RBC's in blood, blood is too viscous (needs dilution) |
|
|
Term
Anemia: Cause and what it really is |
|
Definition
RBC or Hb levels are low. Caused by blood loss, iron deficiency. |
|
|
Term
|
Definition
include fatigue, shallowness of breath. |
|
|
Term
Sickle Cell Disease: What it really is |
|
Definition
Defect in Hb causes it to crystallize if O2 is low or if RBC's are dehydrated. |
|
|
Term
Sickle Cell Disease: What happens as a result |
|
Definition
It causes shape of RBC to distort. |
|
|
Term
Sickle Cell Disease: Symptoms and rate |
|
Definition
Bone and chest pain, stroke. Affects 1 in 400 African Americans. |
|
|
Term
Leukocyte Disorder: Leukemia: What it is |
|
Definition
Cancer from uncontrolled leukocyte formation. |
|
|
Term
|
Definition
Cancer cells take over bone marrow, ruin normal blood cell production. |
|
|
Term
|
Definition
Lymphoblastic, Myeloblastic, Acute, Chronic |
|
|
Term
|
Definition
|
|
Term
|
Definition
Immature cells from myeloid line |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
Platelet disorder: Thrombocytopenia: What it is |
|
Definition
Low concentration of platelets in blood |
|
|
Term
Thrombocytopenia: What happens as a result |
|
Definition
Internal bleeding, diminished clot formation. |
|
|
Term
|
Definition
Can result from cancer treatment (chemotherapy), bone marrow damage. |
|
|
Term
|
Definition
is the organ that destroys platelets (and other blood cells) |
|
|
Term
Erythrocyte: Diameter and thickness |
|
Definition
7.5 nano meters and 2.0 nano meters |
|
|