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Chapter 17
Mechanics of Breathing
55
Physiology
Undergraduate 3
10/28/2015

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Term
cellular respiration
Definition
the intracellular reaction of oxygen with organic materials to produce carbon dioxide, water, & energy in the form of ATP
Term
external respiration
Definition
the movement of gases between the environment & the body's cells
Term
4 processes of external respiration
Definition
1. the exchange of air between the atmosphere & the lungs
2. the exchange of O2 & CO2 between the lungs & the blood
3. the transport of O2 & CO2 by the blood
4. the exchange of gases between blood & the cells
Term
ventilation
Definition
AKA breathing; the exchange of air between the atmosphere & the lungs
Term
inspiration
Definition
the movement of air into the lungs
Term
expiration
Definition
the movement of air out of the lungs
Term
What system consists of structures involved in ventilation & gas exchange?
Definition
the respiratory system
Term
conducting system
Definition
passages (airways) that lead from the external environment to the exchange surface of the lungs
Term
alveoli (alveolus)
Definition
a series of interconnected sacs & their associated pulmonary capillaries
Term
4 parts of the upper respiratory tract
Definition
1. mouth
2. nasal cavity
3. pharynx
4. larynx
Term
4 parts of the lower respiratory tract
Definition
1. trachea
2. two primary bronchi
3. bronchi branches
4. lungs
Term
Is the diaphragm made of skeletal or smooth muscle?
Definition
skeletal
Term
intercostal muscles
Definition
2 sets of muscles (internal & external) that connect the 12 pairs of ribs
Term
Where do the sternocleidomastoids & scalenes run?
Definition
from the head & neck to the sternum & first two ribs
Term
pleural sacs
Definition
two bags that surround the lungs
Term
What makes up most of the volume of the light, spongy tissue of the lungs?
Definition
air-filled spaces
Term
What makes up the pleura (pleural membranes)?
Definition
several layers of elastic connective tissue & numerous capillaries
Term
pleural fluid
Definition
a thin film that holds together the opposing layers of pleural membrane; has a total volume of only about 25-30 mL in the average man
Term
Where does air pass into after it enters the upper respiratory tract through the mouth & nose?
Definition
the pharynx (a common passageway for food, liquids, & air)
Term
From the pharynx, air flows through the _____ into the _____
Definition
larynx; trachea (windpipe)
Term
vocal cords
Definition
connective tissue bands that vibrate & tighten to create sound when air moves past them; in the larynx
Term
Where do the primary bronchi go to?
Definition
one bronchus goes to each lung
Term
bronchioles
Definition
branches of the smallest bronchi within the lungs; small collapsible passageways with walls of smooth muscle
Term
3 components of conditioning
Definition
1. warming air to body temperature
2. adding water vapor until the air reaches 100% humidity
3. filtering out foreign material
Term
type 1 alveolar cells
Definition
make up about 95% of the alveolar surface area; used for gas exchange; larger of the two types of alveolar cells
Term
type II alveolar cells
Definition
smaller & thicker of the two types of alveolar cells; synthesize & secrete a chemical known as surfactant
Term
atmospheric pressure
Definition
environmental air pressure; reported in millimeters of mercury (just like blood pressure)
Term
Dalton's Law
Definition
the total pressure exerted by a mixture of gases is the sum of the pressures exerted by the individual gases
Term
partial pressure (Pgas)
Definition
the pressure of a single gas in a mixture
Term
What two measurements are related in Boyle's Law?
Definition
pressure & volume
Term
respiratory cycle
Definition
an inspiration followed by an expiration
Term
spirometer
Definition
used in pulmonary function tests; an instrument that measures the volume of air moved with each breath
Term
tidal volume (VT)
Definition
the volume of air that moves during a single inspiration or expiration
Term
inspiratory reserve volume (IRV)
Definition
the additional volume you inspire above the tidal volume (forced breathing in after a normal inspiration)
Term
expiratory reserve volume (ERV)
Definition
the amount of air forcefully exhaled after the end of a normal expiration; averages about 1100 mL
Term
residual volume (RV)
Definition
the volume of air in the respiratory system after maximal exhalation; usually about 1200 mL
Term
vital capacity (VC)
Definition
the sum of the inspiratory reserve volume, expiratory reserve volume, & tidal volume
Term
FEV1 (forces expiratory volume in 1 second)
Definition
how fast air leaves the airways in the first second of expiration
Term
total lung capacity
Definition
vital capacity plus the residual volume
Term
active expiration
Definition
during voluntary exhalations when ventilation exceeds 30-40 breaths per minute
Term
pneumothorax
Definition
a condition that results in a collapsed lung that is unable to function normally
Term
compliance
Definition
the ability of the lung to stretch
Term
elastance
Definition
the reciprocal of compliance; the ability to resist being deformed
Term
restrictive lung diseases
Definition
pathological conditions in which compliance is reduced
Term
fibrosis
Definition
a pulmonary disease characterized by the development of stiff, fibrous scar tissue that restricts lung inflation
Term
surface active agents (surfactants)
Definition
molecules that disrupts cohesive forces between water molecules by substituting themselves for water at the surface; reduces surface tension of the lungs
Term
bronchoconstriction
Definition
increases resistance to air flow & decreases the amount of fresh air that reaches the alveoli
Term
bronchodilation
Definition
caused by increased CO2 in expired air which results in relaxation of the bronchiolar smooth muscle
Term
total pulmonary ventilation
Definition
used to estimate the effectiveness of ventilation; the volume of air moved into & out of the lungs each minute
Term
anatomic dead space
Definition
the conducting airways that do not exchange gases with the blood
Term
4 stages of lung volume throughout a respiratory cycle
Definition
1. the end of an inspiration: lung volume is maximal & fresh air from the atmosphere fills the upper airways
2. exhalation: the tidal volume of 500 mL leaves the body
3. end of exhalation: lung volume is at its minimum & stale air from alveoli fills the anatomic dead space
4. next inspiration: another 500 mL of fresh air enters the airways
Term
alveolar ventilation
Definition
a more accurate indicator of ventilation efficiency because a significant portion of inspired air never reaches an exchange surface; the volume of fresh air that reaches the alveoli each minute
Term
How high can maximum voluntary ventilation (breathing as deeply & quickly as possible) increase pulmonary ventilation to?
Definition
170 L/min
Term
obstructive lung diseases
Definition
diseases in which air flow is diminished because of increased airway resistance
Term
asthma
Definition
an inflammatory condition characterized by bronchoconstriction & airway edema; often associated with allergies
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