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an individuals genetically predetermined resistance to certain diseases |
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the ability of the body to specifically react to a microbial infection |
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mature in the bone marrow, produce antibodies |
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mature in the thymus, involved in cell-mediated immunity |
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liquid portion of the blood |
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liquid remaining after blood plasma is clotted |
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the generic term for serium because it contains antibodies |
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a chemical substance that causes the body to produce specific antibodies or sensitied T cells |
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proteins formed against specific regions on antigens |
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epitope, or antigenic determinants |
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low-molecular-weigt substance that cannot cause the formation of antibodies unless combined with a carrier molecule |
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contains 4 polypeptide chains and held together by di-sulfide bonds |
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the stem region of an antibody |
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The constant part of all antibodies |
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most pevalent, fix the complement system,enhance phagocytosis, cross the placenta, monomers and enter tissues |
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consist of five monomers, agglutination and complement fixation, in blood, lymph and on B cells, first antibody in an infection |
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monomer, dimmers that protect mucosal surfaces from invasion, prevalent in body fluids, in breast milk |
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on B cells, in blood and lymph, monomers, initiate the immune response |
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bind to mast cells and basophils (trigger release of histamine), involved in allergic reactions, monomers, lyse parasitic worms, |
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B cells differentiate into |
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strength of the bond between Ag and Ab |
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Ab recognizes a specific epitope |
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when an antibody binds to its specific epitopes on an antigen |
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antibodies attach to microbes or toxins, inhibiting them from adherence |
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results in cell lysis, cascade effect |
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activate ells involved in cellular immunity |
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activate B cells so they can make antibodies |
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activated by endogenous antigens and MHC class I on a tarfget cells and transformed into CTL |
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lyse or induce apoptosis in the target cell |
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lyse virus-infected cells, tumor cells and parasites |
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serve as communicators between leukocytes |
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cause leukocytes to migrate to an infection |
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alpha and beta interferons |
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protect neighboring cells from virus infection by going into the neighboring cell, causing them to make antiviral proteins that block replication of the virus in that cell. |
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tumor necrosis factor (TNF) |
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promotes the inflammatory reaction |
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the relative amount of antibody in serum |
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response of the body to the first contact with an antigen, IgM then IgG |
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the secondary response to an infection, with more and quicker release of antibodies |
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brings in the pathogen in contact with the T and B cels |
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Naturally aquired active immunity |
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immunity resulting from infection |
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Naturally acquired passive immunity |
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antibodies transferred from a mother to a fetus or to a newborn in breast milk |
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artificially acquired active immunity |
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immunity resulting from vaccination |
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artificially aquired passive immunity |
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refers to the humoral antibodies acquired by injection |
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on the plasma membranes of all nucleated cells |
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on the plasma membrane on antigen presenting cells. |
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ingests a microorganism, antigen is processed and comined with MHC class II and are displayed on the surface of the APC |
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cytokines from APC cause Th cell to proliferate |
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receptor on the surface of the Th cell binds to MHC-antigen complex; |
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