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Chapter 16
Endocrine System
93
Health Care
Undergraduate 4
05/02/2011

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Term
pituitary gland, hypophysis cerebri
Definition
approximately the size of a pea and located at the base of the brain. The pituitary is divided into two lobes.
Term
anterior lobe or adenohypohysis
Definition
produces and secretes the following hormones: growth hormone (GH), adrenocorticotropic hormone (ACTH), thyroid-stimulating hormone (TSH), follicle-stimulating hormone (FSH), luteinizing hormone (LH), prolactin or lactogenic hormone (PRL)
Term
growth hormone (GH)
Definition
regulates the growth of the body
Term
adrenocorticotropic hormone (ACTH)
Definition
stimulates the adrenal cortex
Term
thyroid-stimulating hormone (TSH)
Definition
stimulates the thyroid gland
Term
gonadotropic hormones
Definition
affect the male and female reproductive systems
Term
follicle-stimulating hormone (FSH), luteinizing hormone (LH)
Definition
regulate development, growth, and function of the ovaries and testes
Term
prolactin or lactogenic hormone (PRL)
Definition
promotes development of glandular tissue during pregnancy and produces milk after birth of an infant
Term
posterior lobe or neurohypophysis
Definition
stores and releases antidiuretic hormone and oxytocin
Term
antidiuretic hormone (ADH)
Definition
stimulates the kidney to reabsorb water
Term
oxytocin
Definition
stimulates uterine contractions during labor and postpartum
Term
hypothalamus
Definition
located near the pituitary gland in the brain. This secretes "releasing" hormone that functions to stimulate or inhibit the release of pituitary gland hormones.
Term
thyroid gland
Definition
largest endocrine gland. It is located in the neck below the larynx and comprises bilateral lobes connected by an isthmus. The thyroid gland secretes the hormones triiodothyronine (T3) and thyroxine (T4), which require iodine for their production. Thyroxine is necessary for body cell metabolism.
Term
parathyroid glands
Definition
four small bodies lying directly behind the thyroid. Parathormone (PTH), the hormone produced by the glands, helps maintain the level of calcium in the blood
Term
islets of Langerhans
Definition
clusters of endocrine tissue found throughout the pancreas, made up of different cell types that secrete various hormones, including insulin and glucagon. Nonendocrine cells found throughout the pancreas perform nonendocrine functions such as digestion.
Term
adrenal glands, suprarenals
Definition
paired glands, one of which is located above each kidney. The outer portion is called the adrenal cortex, and the inner portion is called the adrenal medulla. The following hormones are secreted by the adrenal glands:
Term
aldosterone
Definition
secreted by the cortex. Electrolytes (mineral salts) that are necessary for normal body function are regulated by this hormone.
Term
epinephrine (adrenaline), norepinephrine (noradrenaline)
Definition
secreted by the medulla. These hormones help the body to deal with stress by increasing the blood pressure, heartbeat, and respirations
Term
aden/o
Definition
gland
Term
adren/o, adrenal/o
Definition
adrenal glands
Term
cortic/o
Definition
cortex (the outer layer of a body organ)
Term
endocrin/o
Definition
endocrine
Term
parathyroid/o
Definition
parathyroid glands
Term
thyroid/o, thyr/o
Definition
thyroid gland
Term
acr/o
Definition
extremities, height
Term
calc/i
Definition
calcium
Term
dips/o
Definition
thirst
Term
kal/i
Definition
potassium
Term
natr/o
Definition
sodium
Term
-drome
Definition

run, running

(prefix)

Term
acromegaly
Definition
enlargement of the extremities (and bones of the face, hands, and feet caused by excessive production of the growth hormone by the pituitary gland after puberty)
Term
adenitis
Definition
inflammation of a gland
Term
adenodynia
Definition
pain in a gland
Term
adenomalacia
Definition
abnormal softening of a gland
Term
adenomegaly
Definition
enlargement of a gland
Term
adenosis
Definition
abnormal condition of a gland
Term
adrenalitis
Definition
inflammation of the adrenal gland
Term
adrenomegaly
Definition
enlargement (of one or both) of the adrenal glands
Term
hypercalcemia
Definition
excessive calcium in the blood
Term
hyperglycemia
Definition
excessive sugar in the blood
Term
hyperkalemia
Definition
excessive potassium in the blood
Term
hyperthyroidism
Definition
state of excessive thyroid gland activity (characterized by excessive secretion of thyroid hormone)
Term
hypocalcemia
Definition
deficient level of calcium in the blood
Term
hypoglycemia
Definition
deficient level of sugar in the blood
Term
hypokalemia
Definition
deficient level of potassium in the blood
Term
hyponatremia
Definition
deficient level of sodium in the blood
Term
hypothyroidism
Definition
state of deficient thyroid gland activity (characterized by decreased secretion of thyroid hormones)
Term
parathyroidoma
Definition
tumor of a parathyroid gland
Term
thyroiditis
Definition
inflammation of the thyroid gland
Term
acidosis
Definition
condition brought about by an abnormal accumulation of acid products of metabolism, seen frequently in uncontrolled diabetes mellitus
Term
Addison disease
Definition
chronic syndrome resulting from a deficiency in the hormonal secretion of the adrenal cortex. Symptoms may include weakness, darkness of skin, loss of appetite, depression, and other emotional problems
Term
cretinism
Definition
condition caused by congenital absence or atrophy of the thyroid gland, resulting in hypothyroidism. The disease is characterized by puffy features, mental deficiency, large tongue, and dwarfism
Term
Cushing syndrome
Definition
group of symptoms attributed to the excessive production or cortisol by the adrenal cortices. This syndrome may be the result of a pituitary tumor. Symptoms include abnormally pigmented skin, "moon face", pads of fat on the chest and abdomen, "buffalo hump" (hump on the upper back), and wasting away of muscle
Term
diabetes insipidus (DI)
Definition
result of decreased secretion of antidiuretic hormone by the posterior lobe of the pituitary gland. Symptoms include excessive thirst (polydipsia) and large amounts of urine (polyuria) and sodium between excreted from the body
Term
diabetes mellitus (DM)
Definition
chronic disease involving a disorder of carbohydrate metabolism. This is caused by underactivity of the islets of Langerhans in the pancreas, which results in insufficient production of insulin. When the disease is not controlled or is untreated, the patient may develop ketosis, acidosis, and finally coma.
Term
gigantism
Definition
condition brought about by overproduction of growth hormone by the pituitary gland before puberty
Term
goiter
Definition
enlargement of the thyroid gland
Term
Graves disease
Definition
a disorder of the thyroid gland characterized by the presence of hyperthyroidism, goiter, and exophthalmos
Term
ketosis
Definition
condition resulting from uncontrolled diabetes mellitus, in which the body has an abnormal concentration of ketone bodies (compounds that re a normal product of fat metabolism)
Term
myxedema
Definition
condition resulting from a deficiency of the thyroid hormone thyroxine. A severe form of hypothyroidism in an adult. Symptoms include puffiness of the face and hands, coarse and thickened skin, enlarged tongue, slow speech, and anemia
Term
tetany
Definition
condition affecting nerves causing muscle spasms as a result of low amounts of calcium in the blood caused by a deficiency of the parathyroid hormone
Term
thyrotoxicosis
Definition
a condition caused by excessive thyroid hormones
Term
adenectomy
Definition
excision of a gland
Term
adrenalectomy
Definition
excision of an adrenal gland
Term
parathyroidectomy
Definition
excision of a parathyroid gland
Term
thyroidectomy
Definition
excision of the thyroid gland
Term
thyroidotomy
Definition
incision of the thyroid gland
Term
thyroparathyroidectomy
Definition
excision of the thyroid and parathyroid glands
Term
radioactive iodine uptake test (RAIU)
Definition
a nuclear medicine scan that measures thyroid function. Radioactive iodine is given to the patient orally, after which its uptake into the thyroid gland is measured.
Term
thyroid scan
Definition
a nuclear medicine test that shows the size, shape, and position of the thyroid gland. The patient is given a radioactive substance to visualize the thyroid gland. An image is recorded as the scanner is passed over the neck area. Used to detect tumors and nodules.
Term
fasting blood sugar (FBS)
Definition
a blood test to determine the amount of glucose (sugar) in the blood after fasting for 8 to 10 hours. Elevation indicates diabetes mellitus.
Term
thyroid-stimulating hormone level (TSH) (thyrotropin)
Definition
a blood test that measures the amount of thyroid-stimulating hormone in the blood. Used to diagnose hyperthyroidism and to monitor patients on thyroid replacement therapy.
Term
thyroxine level (T4)
Definition
a blood study that gives the direct measurement of the amount of thyroxine in the patient's blood. A greater-than-normal amount indicates hyperthyroidism; a less-than-normal amount indicates hypothyroidism
Term
adrenocorticohyperplasia
Definition
excessive development of the adrenal cortex
Term
adrenopathy
Definition
disease of the adrenal gland
Term
calcipenia
Definition
deficiency of calcium (hypocalcemia)
Term
cortical
Definition
pertaining to the cortex
Term
corticoid
Definition
resembling the cortex
Term
endocrinologist
Definition
a physician who studies and treats diseases of the endocrine disease
Term
endocrinology
Definition
the study of the endocrine system (a branch of medicine dealing with diseases of the endocrine system)
Term
endocrinopathy
Definition
(any) disease of the endocrine system
Term
euthyroid
Definition
resembling a normal (functioning) thyroid gland
Term
polydipsia
Definition
abnormal state of much thirst
Term
syndrome
Definition
(set of symptoms that) run (occur) together
Term
exophthalmos
Definition
abnormal protrusion of the eyeball
Term
hormone
Definition
a chemical substance secreted by an endocrine gland that is carried in the blood to a target tissue
Term
isthmus
Definition
narrow strip of tissue connecting two large parts of the body, such as the isthmus that connects the two lobes of the thyroid gland
Term
metabolism
Definition
sum total of all the chemical processes that take place in a living organism
Term
DI
Definition

diabetes insipidus

(abbreviation)

Term
DM
Definition

diabetes mellitus

(abbreviation)

Term
FBS
Definition

fasting blood sugar

(abbreviation)

Term
RAIU
Definition

radioactive iodine uptake

(abbreviation)

Term
T4
Definition

thyroxine level

(abbreviation)

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