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Chapter 16
Innate Immunity: Nonspecific Disease of the Host
20
Microbiology
Undergraduate 2
04/04/2012

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Term
susceptibility
Definition
lack of resistance to a disease
Term
immunity
Definition
ability to ward off disease
Term
innate immunity
Definition
defenses against any pathogen
Term
adaptive immunity
Definition
immunity, resistance to a specific pathogen
Term
IFN-alpha and IFM-beta
Definition
cause cells to produce antiviral proteins that inhibit viral replication
Term
IFN-gamma
Definition
causes neutrophils and macrophages to phagocytize bacteria
Term
Toll-like receptors (TLRs)
Definition
attach to pathogen-associated molecular patterns (PAMPs)
*induce cytokines that regulate the intensity and duration of immune responses
Term
commensal microbiota
Definition
one organism benefits and the other is unharmed
Term
red blood cells
Definition
transport o2 and co2
Term
platelets
Definition
blood clotting
Term
neutriphils
Definition
for phagocytosis (60-70%)
Term
basophils
Definition
release of histamine for inflammatory response
Term
eosinophils
Definition
kills larger parasites
Term
monocytes
Definition
for phagocytosis (3-8%)
Term
dendritic cells
Definition
antigen presenting cells (APC) for phagocytosis
Term
lymphocytes
Definition
NK cells: destroy target cell
T cells: cell-mediated immunity
B cells: production of antibodies
Term
NK cells
Definition
destroy target cell
Term
t cells
Definition
cell-mediated immunity (mature in thymus)
Term
b cells
Definition
production of antibodies
Term
phagocytosis
Definition
neutrophils, fixed macrophages and wandering macrophages
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