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Chapter 15
Chromosomal Basis of Inheritance
20
Biology
Undergraduate 1
01/29/2009

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Term
Chromosome Theory of Inheritance
Definition
Mendelian genes have specific loci (positions) along chromosomes, and it is the chromosomes that undergo segregation
Term
Law of Segregation
Definition
2 alleles for each gene separate during gamete formation
Term
Law of Independent Assortment
Definition
alleles of genes on nonhomologous chromosomes assort independently during gamete formation
Term
Wild Type
Definition
phenotype for a character most commonly observed in natural populations
Term
sex-linked gene
Definition
a gene located on either sex chromosome
Term
Muscular Dystrophy
Definition
disease characterized by a progressive weakening of the muscles and loss of coordination. caused by absence of key muscle protein called dystrophin
Term
Barr Body
Definition
the condensed inactive X in each cell of a female
Term
linked genes
Definition
genes located close enough together on a chromosome that they tend to be inherited together
Term
Genetic Recombination
Definition
the production of offspring with combinations of traits that differ from those found in either parent
Term
parental types
Definition
an offspring with a phenotype that matches one of the parental phenotypes; also refers to the phenotype itself
Term
recombinants
Definition
offspring whose phenotype differs from that of the parents
Term
linkage map
Definition
a genetic map based on the frequencies of recombination between markers during crossing over of homologous chromosomes
Term
genetic map
Definition
an ordered list of genetic loci along a chromosome
Term
crossing over
Definition
the reciprocal exchange of genetic material between nonsister chromatids during prophase I of meiosis
Term
aneuploidy
Definition
a chromosomal aberration in which one or more chromosomes are present in extra copies or are deficient in #
Term
hemizygous
Definition
Term
chromosomal inversion
Definition
an aberration in chromosome structure resulting from reattachment of a chromosomal fragment in a reverse orientation to the chromosome from which it originated
Term
chromosomal translocation
Definition
an aberration in chromosome structure resulting from attachment of a chromosomal fragment to a nonhomologous chromosome
Term
chromosomal duplication
Definition
an aberration in chromosome structure due to fusion with a fragment from a homologous chromosome, such that a portion of a chromosome is duplicated
Term
polyploidy
Definition
a chromosomal alteration in which the organism possesses more tan two complete chromosome sets...result of accidental cell division
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