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Chapter 15 Vocab
genetics
26
Biology
11th Grade
05/12/2008

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Term
chromosome theory of inheritance
Definition
Mendelian genes have specific loci on chromosomes and it is the chromosomes that undergo segregation and independent assortment
Term

wild types

Definition
the phenotype most commonly found in natrual populations
Term
sex-linked genes
Definition
genes located on a sex chromosome
Term
linked genes
Definition
genes located on the same chromosome that tend to be inherited together in genetic crosses because the chromosome is passed along as a unit
Term
genetic recombination
Definition
the production of offspring with new combinations of traits inherited from two parents
Term
parental types
Definition
offspring with a phentype that matches one of the parental phenotypes
Term

recombinants

Definition
offspring with new combinations of alleles different from the parents
Term
genetic map
Definition
an ordered list of the genetic loci along a particular chromosome
Term
linkage map
Definition
a genetic map based on recombination frequencies
Term
map units
Definition
a measurement of the distance between genes;one unit equal to 1% recombination frequency
Term
cytological maps
Definition

locate genes with respect to chromosomal features (can be seen with microscope)

Term
Duchenne muscular dystrophy
Definition
a sex-linked disorder which affects 1 out of every 3500 males in the U.S.; characterized by a weakening of muscles and loss of coordination
Term
hemophilia
Definition
a sex-linked recessive trait defined by the abscence of one or more proteins required for clotting blood
Term
Barr Body
Definition
a dense object lying along the inside of the nuclear envelope in female mammalia cells, representing inactive chromosomes
Term
nondisjunction
Definition
a mishap in which the members of a pair of homologous chromosomes do not move apart properly during meiosis I
Term
aneuploidy
Definition
a chromosomal aberration in which certain chromosomes are present in extra copies or are defecient in number
Term
trisomic
Definition
a chromosomal condition in which a particular cell has an extra copy of one chromosome, instead of two  (has three total copies of a chromosome)
Term
monosomic
Definition
if an aneuploid cell is missing a chromosome (has one total copy)
Term
polyploidy
Definition
having more than two complete chromosome sets (3n or 4n)
Term
deletion
Definition
occurs when a chromosomal fragment lacking a centromere is lost during cell division
Term
duplication
Definition
an aberration which results in a portion of a chromosome fuses with a part of a sister chromatid
Term
inversion
Definition
occurs when a chromosomal fragment reattaches to the original chromosome but in the reverse order
Term
translocation
Definition
a fragment of chromosome may also attach to a nonhomologous chromosome
Term
Down Syndrome
Definition
affects one of every 700 children in the U.S. the result of an extra chromosome 21
Term
genomic imprinting
Definition
a gene on one chromosome is silence, while its allele on the homologous chromosome is left free to be expressed
Term
fragile X syndrome
Definition
a disorder which results in an abnormal X chromosome connected by a thin strand of DNA to another chromosome; children with this condition are mentally retarded
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