Term
| innate vs. adaptive immunity |
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Definition
innate: nonspecific
adaptive: specific |
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Term
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Definition
1. inherited
2. first line of defense |
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Term
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Definition
1. integrates innate and adaptive responses
2. proteins in plasma become activated when antibodies bind to antigens
3. proteins promote phagocytosis, lysis of cells, inflammation |
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Term
phagocytosis
(3 types of cells) |
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Definition
1. neutrophils: first to arrive
2. mononuclear: arrive later
3. organ-specific phagocytes: in organs |
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Term
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Definition
1. antiviral polypeptides produced by infected cells
2. alpha, beta and gamma |
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Term
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Definition
1. acquired ability to defend against specific pathogens after exposure to them
2. mediated by antigens and antibodies |
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Term
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Definition
| 1. cell surface molecules that stimulate the production of specific antibodies |
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Term
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Definition
1. smaller, nontigenic molecules
2. become antigens when bound to other proteins |
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Term
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Definition
1. derived from stem cells in bone marrow
2. seed the thymus, spleen and lymph nodes |
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Term
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Definition
1. attack host cells that have become infected
2. do NOT produce antibodies
3. must be in close proximity to the victim cell in order to destroy it
"cell-mediated immunity" |
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Term
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Definition
1. directly from bone marrow
2. combat Bacterial and some viral infections
3. secrete antibodies
"antibody-mediated immunity" |
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Term
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Definition
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Term
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Definition
1. Y shaped
2. two long, heavy chains joined by two shorter, light chains |
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Term
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Definition
1. destroy body cells that harbor foreign antigens
2. cell-mediated struction |
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Term
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Definition
1. improve ability of B lymphocytes to become plasma cells
2. enhance ability of cytotoxic T cells to kill targets |
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Term
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Definition
1. inhibit response of B and T lymphocytes
2. "supressor T lymphocytes"
3. deficiencies can lead to autoimmune diseases |
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Term
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Definition
1. when exposed to foreign antigens, immune cells respond by making many good copies of themselves
2. to protect against future infections
3. used to make vaccines |
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Term
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Definition
1. killed virus
2. live virus w/attenuated virulence
3. genetically engineered recombinant virus |
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Term
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Definition
1. passing of antibodies from one individual to another
2. temporary protection
- mother to fetus
- mother to child (breast milk)
- immunization |
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Term
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Definition
1. therapeutic antibodies
2. interferons
3. interleukin-2 |
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Term
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Definition
1. autoimmune disease
2. allergies
3. immune complex diseases |
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Term
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Definition
| 1. immune cells fail to tolerate "self" antigens and attack self |
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Term
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Definition
1. hypersensitivity
2. abnormal response to allergens (antigens)
3. immediate and delayed hypersensitivity |
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Term
| immediate hypersensitivity |
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Definition
1. abnormal B cell response
2. seconds to minutes after exposure
3. foods, bee stings, pollen, etc. |
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Term
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Definition
1. abnormal T cell response
2. symptoms 24-72 hours after exposure
3. contact dermititis |
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