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Chapter 14
Gene Activity: How Genes Work
28
Biology
12th Grade
12/12/2006

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Term
One gene=One enzyme
Definition
One gene specifies the synthesis of one enzyme. A single gene was mutilated, resulted in the lack of a single enzyme.
Term
One gene=One polypeptide
Definition
Each gene specifies one polypeptide of a protein, a molecule that may contain one or more different polypeptides.
Term
Gene
Definition
A sequence of DNA nucleotide bases that codes for a product.
Term
Location of DNA
Definition
Nucleus
Term
Ribosomes
Definition
Located in cytoplasm.
Where protein synthesis occurs.
Term
RNA Location
Definition
Ribonucleic acid.
Found in nucleus and cytoplasm and was likely intermediary in protein synthesis.
Term
RNA
Definition
Polymer of nucleotides.
Single-stranded and not a double helix, contains the sugar ribose, and contains the base uracil instead of thymine.
Term
mRNA
Definition
Messenger RNA.
Takes a message from DNA in nucleus to ribosomes in cytoplasm.
Term
rRNA
Definition
Ribosomal RNA.
rRNA and proteins make up ribosomes where proteins are synthesized.
Term
tRNA
Definition
Transfer RNA.
Transfers a particular amino acid to a ribosome.
Doubles bach on itself to create regions where complementary bases are hydrogen-bonded to one another.
Term
Trnascription
Definition
The first step in gene expression.
The process whereby a DNA strand serves as a template for the formation of mRNA.
Term
Trnascription
Definition
The first step in gene expression.
The process whereby a DNA strand serves as a template for the formation of mRNA.
Term
Translation
Definition
An mRNA transcript directs the sequence of amino acids in a polypeptide.
Term
Central dogma
Definition
The sequence of nucleotides in DNA specifies the order of amino acids in a polypeptide.
Term
Genetic code
Definition
A triplet code comprised of 64 three-base code words (codons).
Term
Codon
Definition
Consists of 3 nucleotide bases of DNA that code for an amino acid and allows up to 64 different amino acids to the specified.
There is one start codon and three stop codons.
Term
Unambiguous
Definition
One codon=one meaning
Term
RNA Polymerase
Definition
Enzyme involved in transcription.
Speeds formation of RNA from a DNA template.
Term
Promoter
Definition
Defines the start of the gene, the direction of transcription, and the strand copied.
Term
Transcription process
Definition
RNA polymerase attaches to promoter; complementary RNA nucleotides pair with DNA; association not as stable as helix so only newest portion stays associated, rest dangles off to side; continues until it reaches a DNA terminator.
RNA polymerase molecules work on same DNA strand at same time.
Term
Primary mRNA transcript
Definition
The immediate product of transcription.
Contains exons and introns.
Term
Nucleotide cap
Definition
A modified guanine that tells a ribosome where to attach to begin translation.
Term
Poly-A tail
Definition
Consists of a 150-200 adenine nucleotide chain that facilitates transport of mRNA out of the nucleus and inhibits degradation of mRNA by hydrolytic enzymes.
Protects.
Term
Exon
Definition
A portion of DNA code in primary mRNA transcript eventually expressed as result of polypeptide synthesis.
Term
Intron
Definition
A non-coding segment of DNA removed by spliceosomes before the mRNA leaves nucleus.
May divide a gene into regions that can be joined in different combinations for different products.
Term
Spliceosomes
Definition
A complex that contains several kinds of ribonucleoproteins.
Cut the primary mRNA transcript and then rejoin adjacent exons.
May allow the same DNA to be divided differently and produce different products.
Term
Anticodon
Definition
A group of nucleotides on tRNA that is complementary to the codon on mRNA.
Term
tRNA synthetases
Definition
Amino acid-activating enzymes that recognize which amino acid should join which tRNA molecule, and then catalyze ATP-requiring reactions joining them.
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