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Chapter 13
Complications of Enteral Nutrition
48
Nutrition
Professional
07/19/2016

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Term
What is the maximum hang time for reconstituted powder formulas or formulas in which modular components have been added?
Definition
No more than 4 hours
Term
What are appropriate interventions if delayed gastric emptying is suspected?
Definition
  1. Reducing or discontinuing all narcotic medications
  2. Switching to a low-fat or isotonic formula
  3. Administering the feeding solution at room temperature
  4. Reducing rate of infusion by 20-25 mL/hr
  5. Changing infusion from bolus to continuous
  6. Administering a prokinetic agent such as metoclopramide or erythromycin
Term
What should be done if nausea or vomiting occurs as the rate of administration or bolus volume of EN increases?
Definition
The rate should be reduced to the highest tolerated amount, with an attempt to increase the rate again after symptoms abate
Term
What should be done with an enterally-fed patient with nausea and abdominal distension? Why?
Definition
GRVs should be monitored before each bolus or every 4 hours for continuous feeds. Although elevated GRVs alone do not always correlate with poor tolerance, the combination of an abnormal abdominal exam and elevated GRVs may be significant
Term
What should be done if an enterally-fed patient complains of nausea despite having normal GRVs?
Definition
  1. Anti-emetic medications may help
  2. Patient should be checked for obstruction or fecal impaction, and sometimes even diarrhea
Term
How is abdominal distension diagnosed?
Definition
Visual inspection and palpation as well as objective reports. Careful clinical observation is preferred over objective measures.
Term
What should be done if an enterally-fed patient has abdominal distension (but not nausea/vomiting)?
Definition
  1. Abdominal x-ray to confirm appropriate intestinal anatomy and motility
  2. If intestinal appearance and function are normal, EN may be continued despite distension
  3. Feedings may need to be discontinued if motility is poor or if the bowel is markedly dilated
Term
What are clinical manifestations of maldigestion?
Definition
  1. Bloating
  2. Abdominal distension
  3. Diarrhea
Term
What are diagnostic studies for malabsorption?
Definition
  1. Screening: gross and microscopic examination of stool. Can include measuring fat/protein content.
  2. Intake-output balance: stool collections for quantitative fecal fat study.
  3. Maldigestion-malabsorption of specific nutrients
  4. Endoscopic small bowel biopsy
Term
What are common causes of maldigestion/malabsorption?
Definition
  1. Gluten-sensitive enteropathy
  2. Crohn disease
  3. Diverticular disease
  4. Radiation enteritis
  5. Enteric fistulas
  6. HIV
  7. Pancreatic insufficiency
  8. Short gut syndrome
Term
What are the criteria for diarrhea?
Definition
  1. >500 mL stool output in 24 hours
  2. More than 3 stools per day for at least 2 consecutive days
Term
How can stool volume be measured?
Definition
  1. Placing a collection device in toilet or using a bed pan
  2. Using a rectal tube or by placing a pad under the patient and weighing it after each stool
Term
What are common causes of diarrhea in EN patients?
Definition
  1. Medications (particularly liquid medications with a sorbitol base, antibiotics)
  2. Infection (C diff and nonclostridial bacteria)
Term
How can hypertonic drugs (such as those containing sorbitol) and those which irritate the gut (potassium) be administered to EN patients, and why?
Definition
They should be diluted to avoid inducing dumping-like syndrome
Term
Should EN patients with diarrhea have their formula diluted with water? Why?
Definition
No. It has not been shown to improve tolerance and it may contaminate the formula.
Term
What is the process for managing diarrhea in EN patients?
Definition
  1. Medical assessment of the patient to rule out infectious or inflammatory causes, fecal impaction, problematic medications
  2. Change of formula type
  3. Addition of soluble fiber
  4. Use of an antidiarrheal agent once C diff has been ruled out
  5. Continuation of EN as tolerated and transition to partial PN if necessary
Term
Which patients should be suspected of bacterial overgrowth?
Definition
  1. Roux-en-Y
  2. Those with altered GI anatomy
  3. Those who have been treated with prolonged antibiotics with abdominal symptoms and/or catabolism/hypoalbuminemia
Term
How should powdered EN formulas be prepared to reduce risk of contamination?
Definition
They should be prepared with sterile water in a clean environment
Term
What can be done if there is excess formula left after maximum hang time is reached?
Definition

The remainder can be refrigerated immediately and stored according to manufacturer's recomendations. Note: the volume the is given to the patient should only be the maximum voume that can be used in the given hang time. The rest should be separated IMMEDIATELY and refrigerated for future use (not placed in the patient's room).

 

Term
What should be done to minimize risk of contamination when pouring EN formula from cans into a feeding bag?
Definition
The lids should be cleaned with isopropyl alcohol and allowed to dry before the formula is poured into the bag
Term
How often should the feeding bag itself be changed in a closed system?
Definition
Every 24 hours
Term
What should be done to prevent EN contamination after GRVs have been checked?
Definition
Gloves must be removed and hands must be washed, followed by donning of clean gloves
Term
What can be done to prevent a patient's microorganisms from migrating into the tube feeds?
Definition
  1. Drip chamber
  2. Formula should not remain in delivery system if feeds are not being run
Term
What is the clinical definition of constipation?
Definition
Accumulation of excess waste in the colon, often up to the transverse colon or even the cecum
Term
How can uncomplicated constipation be differentiated from small bowel obstruction or ileus on x-ray?
Definition
With uncomplicated constipation, there is rarely any small bowel dilation
Term
Is chronic stimulant use (e.g. senna) recommended for those with constipation?
Definition
No, because it can result in tachyphylaxis. Chronic stool softener use is OK.
Term
How much fluid should EN patients on a fiber-containing formula receive? Why?
Definition
AT LEAST 1 mL/kcal to prevent constipation
Term
How can fecal impaction present in the elderly?
Definition
Delirium and agitation
Term
What symptoms does fecal impaction present with?
Definition
Fecal impaction should be suspected when stool volumes are small and then become liquid
Term
How does risk of aspiration relate to oropharyngeal secretions, gastric secretions, and GRV?
Definition
Pulmonary aspiration can occur with inhaling of secretions, but it has never been consistently proven to be a consequence of high GRVs
Term
What are risk factors for aspiration in EN patients?
Definition
  1. Low head of bed elevation
  2. Vomiting
  3. G-tube feedings (as opposed to small bowel feeds)
  4. Low Glasgow coma score
  5. GI reflux disease
  6. Malpositioned feeding tube
  7. Transportation within hospital
  8. Inadequate nursing staff
Term
Can patients with dysphagia develop aspiration PNA regardless of gastric contents?
Definition
Yes, by aspirating oropharyngeal secretions
Term
Is use of glucose oxidase strips recommended for detecting aspiration of gastric contents?
Definition
No
Term
How should aspiration of gastric contents be detected?
Definition
A patient who develops dyspnea, cyanosis, and agitation associated with a new infiltrate on chest film should be presumed to have aspiration
Term
How should GRVs be used when monitoring enteral tolerance?
Definition
They are a measure of tolerance but should NOT be used in isolation
Term
How does metabolic acidosis/alkalosis affect serum potassium levels?
Definition
Metabolic acidosis can cause hyperkalemia. Metabolic alkalosis can cause hypokalemia.
Term
How should hypercapnia be addressed in regards to enteral feeding?
Definition
Provide maintenance energy needs only until hypercapnea resolves
Term
What are the risk factors for thiamine deficiency?
Definition
  1. Chronic alcoholism
  2. Advanced age
  3. Long-term malnutrition
  4. Malabsorption
  5. Antacid therapy
  6. Dialysis
Term
Not receiving which type of fatty acid causes EFA deficiency?
Definition
Linoleic acid
Term
What is an easy way to identify dehydration in the elderly? What are the limitations?
Definition
Tongue dryness is a reliable way to identify dehydration in the elderly, provided that medication-induced dryness is ruled out
Term
What laboratory levels are suggestive of dehydration?
Definition
Elevated BUN, plasma osmolality, and hematocrit (sodium can be elevated, low, or normal)
Term
How does muscle mass affect creatinine? What are the clinical implications of this?
Definition
A patient with a very low muscle mass may have a very low baseline creatinine. Thus, a very small increase in creatinine may signify a large decrease in GFR.
Term
How is BUN affected by protein intake? What are the clinical implications?
Definition
BUN reflects protein intake as well as state of hydration and renal function. A patient with no protein intake and renal failure may still have a relatively low BUN.
Term
How can specific gravity and urine output volume reflect dehydration? What alternative measures are there?
Definition
A high specific gravity and low urine output reflects dehydration. Urine color is also an effective, although less precise, measure of hydration.
Term
What is an appropriate amount of urine output for adults?
Definition
1-2 mL/kg/hr
Term
How should fluid needs be altered by fever?
Definition
Increase fluid intake by 12% per degree celsius above 37.8 degrees C
Term
How does glycemic control influence fluid needs?
Definition
Patients with hyperglycemia require more fluid
Term
How does lactation affect fluid needs?
Definition
Lactating women have increased fluid needs
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