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Chapter 13
Skeletal Muscle Relaxants
17
Pharmacology
Undergraduate 3
09/20/2012

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Term
what are seletal muscle relaxants used for?
Definition
  • to decrease muscle spasm or spasticity
  • depressing CNS
  • may also cause blockage of nerve impulses
Term
what is a muscle spasm?
Definition
sudden, involuntary, painful muscle contraction that occurs with musculoskeletal trauma or inflammation
Term
what is spasticity?
Definition
increased muscle tone or contraction and stiff awkward movements
Term
 what indications do we have to used skeletal muscle relaxants?
Definition
  • used primarily in conjuction with other tx measures such as physical therapy
  • used to help relieve spasticity that causes severe pain
Term
what are contraindictations to using skeletal muscle relaxants?
Definition
  • impaired renal/kidney function
  • respiratory depression
  • pt who must be alert for ADLs
Term
What are three skeletal muscle relaxants?
Definition
  • baclofen (Lioresal)
  • cyclobenzapine (Flexeril)
  • methocarbamol (Robaxin)
Term
what is baclofen used for?
Definition
to treat spasticity; increases the effects of gammaaminobutyric acid
Term
how is baclofen given?
Definition
can be given oral or IT
Term
what are effects of baclofen?
Definition
adverse effects: drowsiness, confusion, constipation, fatigue
Term
what is a rule about baclofen?
Definition
needs to be discontinued slowly
Term
what is cyclobenzapine used for?
Definition
to relieve discomfort from acute, painful musculoskeletal disorders
Term
how is cyclobenzapine given?
Definition
orally
Term
what are adverse effects of cyclobenzapine?
Definition
drowsiness, dizziness, dry mouth
Term
what is a rule to using cyclobenzapine?
Definition
indicated for short term use <3 weeks
Term
what is methocarbamol used for?
Definition
to relieve discomfort from acute, painful musculoskeletal disorders
Term
how is methocarbamol given?
Definition
PO, IM, or IV
Term
what are adverse effects of methocarbamol?
Definition
  • drowsiness, dizziness, urticaria
  • may give urine a green, brown, or black color
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