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Allosteric effector A small molecule that binds to a regulatory protein and changes its DNA-binding activity. |
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The ability to create different mRNA molecules encoding different polypeptides by combining different sets of exons from a single kind of pre-mRNA. |
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Inactivation of an operon in the presence of a metabolic end product of the operon |
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Local opening of chromatin structure to allow for gene expression. |
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Describes a gene that is always expressed at approximately the same level. |
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A large complex of regulatory proteins that stabilizes binding of RNA polymerase to a promoter and allows for initiation of transcription. |
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In eukaryotes, a regulatory DNA sequence that can increase transcription from a promoter by binding to an activator protein. |
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The ability of cells to adjust levels of gene expression in response to developmental cues and changes in the environment. |
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A small molecule that allosterically inactivates a repressor and allows expression of a gene or set of genes. |
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Describes a gene that is normally turned off but can be turned on in the presence of a small molecule. |
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Stimulation of gene expression by inactivation of a repressor by a small molecule. |
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A system of regulated gene expression in which binding of a regulatory protein decreases gene expression. |
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In prokaryotic gene expression, a DNA segment near the promoter to which regulatory proteins bind and modulate activity of the promoter. |
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n prokaryotes, a set of adjacent genes that are transcribed as a polycistronic mRNA and that are coordinately regulated. |
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A system of regulated gene expression in which binding of a regulatory protein increases gene expression. |
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Repressible Describes a gene that is normally turned on but can be turned off in the presence of a small molecule. |
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A protein that binds to a DNA regulatory element and inhibits transcription of a gene or genes. |
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Phenomenon in which expression of a single gene is silenced by introduction of a double-stranded RNA sequence corresponding to part of the mRNA. |
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A DNA sequence regulatory element that can decrease transcription from a promoter by binding to a repressor. |
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A diffusible protein that binds to a specific DNA sequence on a gene resulting in a change in gene expression. |
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