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Chapter 12- structure and function of the Neurologic System
Chapter 12
44
Pathology
Professional
09/02/2010

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Term
Sympathetic
Definition
"fight, flight or fright"
Activated during exercise, excitement and emergencies
-blood vessel walls receive only sympathetic stimulation, so at rest, sympathetic is responsible for maintenance of blood pressure
Term
Parasympathetic
Definition
"rest, digest"
-concerned with conserving energy
Term
Anatomical differences in sympathetic vs. parasympathetic divisions
Definition
length of postganglionic fibers
-Sympathetic long fibers
-Parasympathetic short fibers
Branching of axons
- Sym.- highly branched, influences many organs
- parasym.- few branches, localized effect
Term
Neurotransmitter released by preganglionic axons
Definition
Acetylcholine for both branches
- receptor is cholinergic
Term
Neurotransmitter released by postganglionic axons
Definition
Sympathetic- most release norepinephrine, the receptor is adrenergic
Parasympathetic- release acetylcholine
Term
Adrenergic Receptor subtypes- Alpha
Definition
- excitatory except in the gut
-alpha 1- (postsynaptic)- blood vessels, eye, sphinter, genitals, bladder, gut, liver, heart

-alpha 2-( presynaptic in PNS, pere- and postsynaptic in CNS)- blood vessels, pancreas, platelets
Term
Adrenergic receptor subtypes- Beta
Definition
inhibitory except in the heart
- Beta1- heart, kidney
-Beta 2- lungs, vascular, gastrointestinal, genitourinary smooth muscle
-Beta 3- adipose
Term
Cells of the Nervous System
Definition
Neurons- excitable cells that transmit electrical signals
-variable in size
- Microtubules, neurofibrils, microfilaments

Supporting Cells- cells that surround and wrap neurons
Term
Supporting cells
Definition
(Neuroglia or glial cells)
-provide supportive for neurons
-segregate and insulate neurons
-guide young neurons to the proper connections
-promote health and growth
Term
glial cells include
Definition
schwann cells
satellite cells
Term
In the CNS the neuroglial cells include-
Definition
Astrocytes
oligodendrites
microglia
epindymal cells
Term
General Functions of Supporting cells
Definition
-protect the neuron
-Mylinate the cytoplasmic extentions of the neurons (oligodendrites and schwann cells)
Term
Similarity and Differences between neuroglia and neurons
Definition
Similarity- they have fibrous cellular extentions
differences- They cannot generate or transmit nerve impulses
Term
Astrocytes
Definition
highly branched glial cells
functionally- support neurons, anchor neurons to their nutrient supplies
- guide migration of young neurons
- control chemical environment
Term
Microglia Cells
Definition
small, ovoid cells with spiny processes
-Phagocytes that monitor the health of neurons
Term
Ependymal cells
Definition
range in shape from squamous to columnar
-they line the central cavities of the brain and spinal column
Term
define Oligodendrocytes, Schwann cells, and Satellite cells
Definition
Oligodendrocytes- branched cells that wrap CNS nerve fibers
Schwann cells- (neurolemmocytes)- surround fibers of the PNS. forms the myelin sheath
Satellite cells - surround neuron cell bodies with ganglia
Term
The Neurons- identify the structural units of the nervous system
Definition
Answer is in slide show titled as The Neurons ( nerve Cells)
Term
What is the 3 components of the neuron?
Definition
Cell body, dendrites, Axons
Term
Cell body?
Also what is the densely packed bodies in the PNS and CNS called?
Definition
-located mainly in the CNS
-Densely packed bodies in the CNS are nuclei
_Densely packed bodies in the PNS are ganglia
Term
Dendrites
Definition
receptive portion of the neuron
Term
Axons
Definition
-carry nerve impulses away from the cell body
Term
Axons-
Explain what is?- Axon hillock, Initial segment of the axon, myelin, Endoneurium, and Neurilemma
Definition
Axon hillock- cone shaped, nissl free ara, where the axon leaves the cell body
Initial segment of the axon- area of the axon that has the lowest threshold for stimulation, so the action potentials start at this point

myelin- segmented layer of lipid material, insulating substance, formed and maintained by the schwann cell

Endoneurium- delicate layer of connective tissue around each axon
Neurilemma- thin layer between the myelin sheath and the endoneurium
Term
Explain what the nodes of Ranvier is, which is located within the axon?
Definition
regular interruptions of the myelin sheath
Term
Explain the 3 different characteristics that takes place within the the neuron? (i.e. convergence)
Definition
Saltatory conduction- the flow of ions between segments of the myelin rather than along the entire length of the axon

Divergence- ability of branching axons to influence many neurons

Convergence- branches of numerous neurons converging on one or a few neurons
Term
Nerve cell body (Perikaryon or Soma)
Definition
- contains te nucleus and a nucleolus
no centrioles
well developed nissl bodies (rough ER)
contains an axon hillock
Term
Axon Functions
Definition
-Generate and transmit action potentials
-secrete neurotransmitters from the axonal terminals
Term
How does movement occur in the axon?
Definition
Antegrade- toward axonal terminal

Retrograde- away from axonal terminal
Term
Myelin Sheath- what is it? what is the function? how was it formed?
Definition
-whitish, fatty, segmented sheath around most long axons
function- protect the axon, electrically insulate fibers from one another, increase the spend of nerve impulse transmission
-formed b schwann cells in PNS
Term
A Schwann cell
Definition
-envelopes an axon in a trough
-encloses the axon with its plasma membrane
Neurilemma- remaining nucleus and cytoplasm of a schwann cell
Term
Nodes of Ranvier (Neurofibral nodes)
Definition
-gaps in the myelin sheath between adjacent schwann cells
- they are the sites where axon collaterals can emerge
Term
Axons of the CNS
Definition
-both myelinated and unmyelinated fibers are present
-no neurilemma
myelin sheaths are formed by oligodendrocytes
- nodes of ranvier are widely spread
Term
Axons of the CNS
Definition
-both myelinated and unmyelinated fibers are present
-no neurilemma
myelin sheaths are formed by oligodendrocytes
- nodes of ranvier are widely spread
Term
Axons of the CNS
Definition
-both myelinated and unmyelinated fibers are present
-no neurilemma
myelin sheaths are formed by oligodendrocytes
- nodes of ranvier are widely spread
Term
Axons of the CNS
Definition
-both myelinated and unmyelinated fibers are present
-no neurilemma
myelin sheaths are formed by oligodendrocytes
- nodes of ranvier are widely spread
Term
Axons of the CNS
Definition
-both myelinated and unmyelinated fibers are present
-no neurilemma
myelin sheaths are formed by oligodendrocytes
- nodes of ranvier are widely spread
Term
Axons of the CNS
Definition
-both myelinated and unmyelinated fibers are present
-no neurilemma
myelin sheaths are formed by oligodendrocytes
- nodes of ranvier are widely spread
Term
Axons of the CNS
Definition
-both myelinated and unmyelinated fibers are present
-no neurilemma
myelin sheaths are formed by oligodendrocytes
- nodes of ranvier are widely spread
Term
Axons of the CNS
Definition
-both myelinated and unmyelinated fibers are present
-no neurilemma
myelin sheaths are formed by oligodendrocytes
- nodes of ranvier are widely spread
Term
Axons of the CNS
Definition
-both myelinated and unmyelinated fibers are present
-no neurilemma
myelin sheaths are formed by oligodendrocytes
- nodes of ranvier are widely spread
Term
Axons of the CNS
Definition
-both myelinated and unmyelinated fibers are present
-no neurilemma
myelin sheaths are formed by oligodendrocytes
- nodes of ranvier are widely spread
Term
Regions of the brain and spinal cord
Definition
white matter- dense collections of myelinated
gray matter- mostly soma and unmyelinated fibers
Term
Neuron classification
Definition
Multipolar- 3 or more processes
Bipolar- 2 processes (axon dendrite) attached to cell body

Unipolar- single, short process that divides to form peripheral and central processes

Pseudounipolar- single, short process that divides to form 2 or more axon like processes
Term
Neuron functional classification
Definition
Sensory (afferent)- transmit impulses toward the CNS
Motor (efferent)- carry impulses away from the CNS
Interneurons (association neurons)- shuttle signals through CNS pathways
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