Term
| What does the abbreviation “DNA Pol” represent in molecular biology? |
|
Definition
|
|
Term
|
Definition
|
|
Term
| What is the function of DNA Pol III? |
|
Definition
DNA Pol III synthesizes new DNA at the replication fork (“elongation”).
|
|
|
Term
| In what direction is DNA synthesized by DNA polymerases? |
|
Definition
|
|
Term
| What is the function of DNA Pol I? |
|
Definition
DNA Pol I removes the RNA primers made by primase and fills with DNA.
|
|
|
Term
What is the function of the primers that are synthesized by primase in the
replication fork? |
|
Definition
The primers synthesized by primase provide 3' ends of RNA, to which DNA Pol
III adds nucleotide residues during DNA synthesis.
|
|
|
Term
What is the processivity factor of the DNA Pol III holoenzyme and how does
this factor promote processivity? |
|
Definition
| The β-subunit of the DNA Pol III holoenzyme promotes processivity by encircling DNA through noncovalent dimerization. |
|
|
Term
| What does the acronym “SSB” represent in molecular biology? |
|
Definition
| single-stranded binding protein |
|
|
Term
Draw the ligase reaction, labeling the oxygens that participate in the reaction
according to their numbering in the sugar residues.
|
|
Definition
|
|
Term
| What limitation of DNA replication necessitates telomerase? Include a diagram. |
|
Definition
|
|
