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Chapter 12
The Cell Cycle
38
Biology
Not Applicable
05/06/2005

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Term
cell division
Definition
reproduction of cells
Term
genome
Definition
cell's total hereditary endowment of DNA
Term
somatic cells
Definition
all body cells except the reproductive cells
Term
gametes
Definition
reproductive cells
Term
chromatin
Definition
DNA-protein complex
Term
sister chromatids
Definition
replicated forms of a chromosome joined together by the centromere and eventually separated during mitosis and meiosis II
Term
Centromere
Definition
chromosome's narrow "waist"
Term
Mitosis
Definition
division of nucleus
Term
cytokinesis
Definition
division of cytoplasm
Term
meiosis
Definition
variation of cell division, producing gametes
Term
mitotic (M) phase
Definition
includes both mitosis and cytokinesis; shortest part of the cell cycle
Term
interphase
Definition
accounts for 90% of the cycle; cell grows and copies it's chromosome in preparation for cell division
Term
G1 phase (first gap)
Definition
first growth phase of the cell cycle, consisting of the portion of interphase befor DNA synthesis begins
Term
S phase
Definition
synthesis phase of the cell cycle, constituting the portion of interphase during which DNA is replicated
Term
G2 Phase (second gap)
Definition
second growth phase of the cell cycle
Term
Prophase
Definition
the first phase of mitosis or of one of the divisions of meiosis. During this phase the chromosomes condense and become visible.
Term
Prometaphase
Definition
The stage of mitosis or meiosis in which the nuclear membrane disintegrates, the centrioles reach the poles of the cell, and the chromosomes continue to contract.
Term
metaphase
Definition
The stage of mitosis and meiosis, following prophase and preceding anaphase, during which the chromosomes are aligned along the metaphase plate.
Term
anaphase
Definition
The stage of mitosis and meiosis in which the chromosomes move to opposite ends of the nuclear spindle.
Term
telophase
Definition
The final stage of mitosis or meiosis during which the chromosomes of daughter cells are grouped in new nuclei.
Term
mitotic spindle
Definition
consisting of microtubules, some of which become attached to each chromosome at its centromere and provide the mechanism for chromosomal movement
Term
kinetochore
Definition
structue of proteins and specific sections of chromosomal DNA at the centromere
Term
metaphase plate
Definition
plane that's between the two poles of the dividing cell
Term
cleavage furrow
Definition
groove intehe cell's surface
Term
cell plate
Definition
double membrane across the midline of a dividing plant cell, between which the new cell wall forms during cytokinesis
Term
binary fission
Definition
cell division used by prokaryotes
Term
cell-cycle control system
Definition
cyclically operating set of molecules in the cell that both triggers and coordinates key events in the cell cycle
Term
checkpoint
Definition
critical control point where stop and go-ahead signals can regulate the cycle
Term
G0 phase
Definition
nondividing state that occurs if not approved by G1 checkpoint
Term
cyclin
Definition
protein; cyclically fluctuating concentration in the cell
Term
cyclin-dependant kinases (Cdks)
Definition
kinases
Term
growth factor
Definition
protein released by certain body cells that stimulates other cells to divide
Term
density-dependent inhibition
Definition
any factor influencing population regulation that has a greater impact as population density increases
Term
anchorage dependence
Definition
to divide, animal cells must be attached to a substratum
Term
tumor
Definition
mass of abnormal cells within an otherwise normal tissue
Term
benign tumor
Definition
abnormal cells that remain at the original site
Term
malignant tumor
Definition
invasive tumor that impairs the functions of one or more organs
Term
metastasis
Definition
spread of cancer cells beyond their original site
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