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Chapter 12: Learning & Memory
Chapter 12: Learning & Memory
23
Physiology
Undergraduate 4
11/15/2011

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Term
Need to know
Definition
17, 22
Term
Perceptual learning
Definition
The ability to recognize stimuli that have been perceived before
-caused by changes in sensory systems
Term
Stimulus-response learning
Definition
Learning to make a particular response in the presence of a specific stimulus
-caused by changes b/w sensory and motor systems
-includes classical and instrumental conditioning
Term
Motor learning
Definition
Learning to make a new response
-caused by changes in the motor systems
Term
Relational learning
Definition
Learning relationships b/w individual stimuli
Term
Hebb rule
Definition
On a cellular level, a synapse is strengthened that is repeatedly active when the postsynaptic neuron is firing
-related to classical conditioning
Term
Long-term potentiation (LTP)
Definition
An increase in the excitability of a neuron to a specific synaptic input that is caused by consistent activity of that input
Term
Which NT is majorly involved in LTP?
Definition
Glutamate
Term
NDMA receptors
Definition
Ionotropic glutamate receptor that is responsible for LTP
-controls a calcium (Ca+) channel that is normally blocked by Mg2+ (Magnesium) ions
Term
Associative long-term potentiation
Definition
An LTP that strengthens a weak synapse because it was stimulated simultaneously with a strong one
Term
Dendritic spike
Definition
An AP that sends a depolarizing signal up the dendrite
Term
AMPA receptor
Definition
Ionotropic glutamate receptor that produces EPSPs when open
-controls a Sodium (Na+) channel
Term
Long-term depression (LTD)
Definition
A decrease in the excitability of a neuron to a particular synaptic input
-caused by stimulation of the terminal when the postsynaptic membrane is hyperpolarized
Term
Why does perceptual learning occur?
Definition
As a result of changes in synaptic connections w/in the sensory association cortex
Term
Which dopamine (DA) system is involved with instrumental conditioning and motor learning?
Definition
Mesolimbic DA system
Term
Mesolimbic DA system
Definition
Involved in reinforcing effects/reward signal
Term
What are 2 causes for anterograde amnesia?
Definition
-Head injury
-degenerative brain disease
Term
What are 2 causes of retrograde amnesia?
Definition
-Head injury
-Electroconvulsive shock
Term
Korsakoff's syndrome
Definition
Permanent anterograde amnesia
-caused by brain damage due to alcoholism or malnutrition
Term
Consolidation
Definition
Process by which short-term memories are converted into long-term memories
Term
Which 3 types of learning did H.M. still have after surgery?
Definition
-Perceptual learning
-Sensory-response learning
-Motor learning
Term
Declarative memory
Definition
Memory that can be verbally expressed, such as events
-explicit
Term
Nondeclarative memory
Definition
A collective term for perceptual, stimulus-response, and motor memory
-does not depend on the hippocampal formation
-implicit
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