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(association neurons) integration between motor and sensory neurons nerve impulses travel from one area of CNS to another area of CNS axon, cell body and dendrites all in CNS |
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point of close proximity between two neurons and neuron and effector cell |
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____ of one neuron forms synapse with _____ or cell body of another neuron |
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neuron carrying nerve impulse toward synapse |
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neuron carrying nerve impulse away from synapse receives info at the synapse |
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effector cell receives impulse at synapse |
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connected by gap junctions transmission is rapid less common synchronizes activity of groups of cells location: cardiac and smooth muscle, embryonic neurons, few regions of adult brain |
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connect cytosol of adjacent neurons allows ions and small molecules to pass from one neuron to next |
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neurons do not touch Neurotransmitter must diffuse across space between presynaptic neuron and postsynaptic neuron cell |
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fluid filled space separating axon terminal of presynaptic neuron from: -PM of postsynaptic neuron(cell body or dendrite) -PM of postsynaptic cell (effector) prevents electrical signals from passing directly from neuron to neuron |
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resting membrane potential |
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electrical difference across the plasma membrane of a resting neuron measured in voltage maintained by the sodium-potassium pump |
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energy difference in RMP is due to separation of _____ and _____ |
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only ___ and ____ alter their membrane potential as a result of stimulation |
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separation of oppositely charged molecules is a form of ______ energy |
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average for resting potential |
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in RMP, carrier protein transports ions against concentration gradient using ATP. This is known as ____ ____. |
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In RMP: ____ diffuses into cell, while _____ diffuses out of cell through LEAKAGE channels in plasma membrane |
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two types of signals produced by change in membrane potential |
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incoming signals travel short distances |
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outgoing signals travel long distances |
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inside of plasma membrane becomes less negative than RMP cell is less polarized (-70mV)-->(-35mV)-->(0 mV)-->(30mV) |
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inside of plasma membrane becomes more negative than RMP cell is more polarized (-70mV)--> (-90mV) |
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inside of plasma membrane returns to RMP internal negativity or polarization is restored (30mV)-->(0mV)-->(-35mV)-->(-70mV) |
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short-lived, localized changes in membrane potential depolarization or hyperpolarization that occurs on dendrite or cell body of neuron decreases in magnitude with distance magnitude varies with strength of distance |
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stronger the stimulus, the more ____ channels, and the farther the graded potential travels |
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degree of polarization is determined by amount of ___ entering cell |
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greater the ______, the farther the graded potential can travel before dying out |
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triggered by a change in the neuron environment-->stimulus |
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(in graded potentials) Na enters the cell, moving down concentration gradient |
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time during which a THRESHOLD STIMULUS can NOT produce an action potential Na+ channels are closed and will NOT open despite strength of stimulus RMP is being restored Ensures 2nd AP will not occur before 1st has finished |
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movement of AP is much faster in myelinated axons myelin sheath prevents contact with ECF only Nodes of Ranvier are exposed to ECF Voltage-gated Na+ channels are concentrated at Nodes AP generated only at nodes and jump from node to node |
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myelin sheath prevents contact with ______ |
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only this is exposed to the ECF |
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refractory period is time in which the ______ _____ can NOT produce an action potential |
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what is an action potential that occurs on an axon? |
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what causes synaptic vesicles to fuse with axon terminal plasma membrane (occurs at synaptic cleft) |
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Neurotransmitter is released into synaptic cleft via ______ |
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Neurotransmitter diffuses across synaptic cleft and binds to ____ _____ on plasma membrane of postsynaptic neuron/cell |
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excitatory postsynaptic potential inhibitory postsynaptic potential |
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two types of postsynaptic potentials (GPs) |
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GPs is depolarization or hyperpolarization that occurs on ____ or _____ of the neuron |
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cat: GP ion channels only open at site of _____ ______ |
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occur at maximum levels or not at all |
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a single EPSP is not strong enough to generate an action potential so it must ____ to generate ATP |
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one or more presynaptic neurons must release NT in rapid succession. first NT produces small EPSP before EPSP dissipates, more NT is released |
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postsynaptic neuron stimulated by NT released from many axon terminals at same time |
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NTs that are: inhibitory or excitatory released by all neurons that stimulate skeletal muscle released by some neurons of ANS |
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norepinephrine and epinephrine |
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NTs that are: excitatory or inhibitory released in both CNS and PNS |
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two types of neural circuits |
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neuronal circuit: one neuron stimulates increasing numbers of neurons (amplifying) |
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neuronal circuit: results in either strong stimulation or inhibition |
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molecule binds to receptor protein in place of NT and excites or inhibits postsynaptic neuron mimics effects of NT (many illegal drugs) |
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molecule binds to receptor protein in place of NT but results in No effect (many poisons) |
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